| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 4/7/1985 | SOP | Dopson | Promoted to active roster | | | Before |
| 4/7/1985 | SOP | Sanderson | Placed on Injured List | | 4/7/1985 | Before |
| 4/16/1985 | ROC | O'Brien,C | Promoted to active roster | | | Before |
| 4/16/1985 | ROC | Tettleton | Placed on Injured List | | 4/15/1985 | Before |
| 4/17/1985 | QME | Correa | Demoted to reserve roster | | | Before |
| 4/17/1985 | QME | Guzman | Promoted to active roster | | | Before |
| 4/25/1985 | HNT | Coleman | Promoted to active roster | | | Before |
| 4/25/1985 | HNT | McGee | Placed on Injured List | | 4/24/1985 | Before |
| 4/25/1985 | HNT | Moreno | Promoted to active roster | | | Before |
| 4/25/1985 | HNT | Rawley | Placed on Injured List | | 4/23/1985 | Before |
| 4/25/1985 | HNT | Terrell | Promoted to active roster | | | Before |
| 4/25/1985 | HNT | White,D | Demoted to reserve roster | | | Before |
| 4/25/1985 | TWP | Gardenhire | Promoted to active roster | | | Before |
| 4/25/1985 | TWP | Ramirez,R | Placed on Injured List | | 4/25/1985 | Before |
| 4/26/1985 | TWP | Lamp | Placed on Injured List | | 4/20/1985 | Before |
| 4/26/1985 | TWP | Smithson | Promoted to active roster | | | Before |
| 5/1/1985 | HNT | Kison | Promoted to active roster | | | Before |
| 5/1/1985 | HNT | Schmidt,D | Placed on Injured List | | 5/1/1985 | Before |
| 5/1/1985 | ROC | O'Brien,C | Demoted to reserve roster | | | Before |
| 5/1/1985 | ROC | Tettleton | Activated from Injured List | | | Before |
| 5/2/1985 | RIN | Farr | Demoted to reserve roster | | | Before |
| 5/2/1985 | RIN | Lucas | Promoted to active roster | | | Before |
| 5/4/1985 | AVI | Guante | Demoted to reserve roster | | | Before |
| 5/4/1985 | AVI | Henry | Promoted to active roster | | | Before |
| 5/4/1985 | HNT | Tanana | Placed on Injured List | | 5/4/1985 | Before |
| 5/4/1985 | HNT | Trout | Promoted to active roster | | | Before |
| 5/5/1985 | TWP | Lamp | Activated from Injured List | | | Before |
| 5/5/1985 | TWP | Smithson | Demoted to reserve roster | | | Before |
| 5/6/1985 | QME | Fielder | Demoted to reserve roster | | | Before |
| 5/6/1985 | QME | Perez,T | Promoted to active roster | | | Before |
| 5/8/1985 | SAN | Garber | Promoted to active roster | | | Before |
| 5/8/1985 | SAN | Gossage | Placed on Injured List | | 5/8/1985 | Before |
| 5/8/1985 | SOP | Dopson | Demoted to reserve roster | | | Before |
| 5/8/1985 | SOP | Griffey | Placed on Injured List | | 5/7/1985 | Before |
| 5/8/1985 | SOP | Nettles | Promoted to active roster | | | Before |
| 5/8/1985 | SOP | Sanderson | Activated from Injured List | | | Before |
| 5/9/1985 | HNT | McGee | Activated from Injured List | | | Before |
| 5/9/1985 | HNT | Moreno | Demoted to reserve roster | | | Before |
| 5/9/1985 | TWP | Galarraga | Demoted to reserve roster | | | Before |
| 5/9/1985 | TWP | Gardenhire | Demoted to reserve roster | | | Before |
| 5/9/1985 | TWP | Wilkerson | Promoted to active roster | | | Before |
| 5/10/1985 | TWP | Ramirez,R | Activated from Injured List | | | Before |
| 5/10/1985 | TWP | Wilkerson | Demoted to reserve roster | | | Before |
| 5/12/1985 | RIN | Bream | Demoted to reserve roster | | | Before |
| 5/12/1985 | RIN | Clear | Demoted to reserve roster | | | Before |
| 5/12/1985 | RIN | Hudler | Promoted to active roster | | | Before |
| 5/12/1985 | RIN | Thompson,R | Promoted to active roster | | | Before |
| 5/12/1985 | SAN | Hume | Promoted to active roster | | | Before |
| 5/12/1985 | SAN | Sutcliffe | Placed on Injured List | | 5/9/1985 | Before |
| 5/14/1985 | AVI | Guante | Promoted to active roster | | | Before |
| 5/14/1985 | AVI | Ontiveros | Placed on Injured List | | 5/14/1985 | Before |
| 5/15/1985 | SAN | Cerone | Promoted to active roster | | | Before |
| 5/15/1985 | SAN | Skinner | Demoted to reserve roster | | | Before |
| 5/16/1985 | ROC | Hulett | Placed on Injured List | | 5/16/1985 | Before |
| 5/16/1985 | ROC | Oliver | Promoted to active roster | | | Before |
| 5/20/1985 | QME | Martinez,D | Placed on Injured List | | 5/18/1985 | Before |
| 5/20/1985 | QME | Palmer | Promoted to active roster | | | Before |
| 5/21/1985 | AVI | Cary | Promoted to active roster | | | Before |
| 5/21/1985 | AVI | Cowens | Demoted to reserve roster | | | Before |
| 5/22/1985 | QME | Gruber | Promoted to active roster | | | Before |
| 5/22/1985 | QME | Tartabull | Demoted to reserve roster | | | Before |
| 5/23/1985 | RIN | Mazzilli | Promoted to active roster | | | Before |
| 5/23/1985 | RIN | Ortiz | Promoted to active roster | | | Before |
| 5/23/1985 | RIN | Strawberry | Demoted to reserve roster | | | Before |
| 5/23/1985 | ROC | Fingers | Demoted to reserve roster | | | Before |
| 5/23/1985 | ROC | Flanagan | Promoted to active roster | | | Before |
| 5/23/1985 | ROC | Howe,S | Demoted to reserve roster | | | Before |
| 5/23/1985 | ROC | Wilcox | Promoted to active roster | | | Before |
| 5/24/1985 | HNT | Kison | Demoted to reserve roster | | | Before |
| 5/24/1985 | HNT | Schmidt,D | Activated from Injured List | | | Before |
| 5/24/1985 | HNT | Tanana | Activated from Injured List | | | Before |
| 5/24/1985 | HNT | Trout | Demoted to reserve roster | | | Before |
| 5/24/1985 | SOP | Griffey | Activated from Injured List | | | Before |
| 5/24/1985 | SOP | Roenicke,R | Demoted to reserve roster | | | Before |
| 5/26/1985 | ROC | Guerrero | Placed on Injured List | | 5/26/1985 | Before |
| 5/26/1985 | ROC | Washington,UL | Promoted to active roster | | | Before |
| 5/29/1985 | AVI | Henry | Demoted to reserve roster | | | Before |
| 5/29/1985 | AVI | Ontiveros | Activated from Injured List | | | Before |
| 6/1/1985 | AVI | Carter,J | Placed on Injured List | | 5/31/1985 | Before |
| 6/1/1985 | AVI | Cowens | Promoted to active roster | | | Before |
| 6/1/1985 | ROC | Hulett | Activated from Injured List | | | Before |
| 6/1/1985 | ROC | Oliver | Demoted to reserve roster | | | Before |
| 6/3/1985 | QME | Gruber | Demoted to reserve roster | | | Before |
| 6/3/1985 | QME | Puhl | Promoted to active roster | | | Before |
| 6/4/1985 | QME | Martinez,D | Activated from Injured List | | | Before |
| 6/4/1985 | QME | Palmer | Demoted to reserve roster | | | Before |
| 6/4/1985 | SAN | Diaz,C | Demoted to reserve roster | | | Before |
| 6/4/1985 | SAN | Gossage | Activated from Injured List | | | Before |
| 6/4/1985 | SAN | Reuss | Demoted to reserve roster | | | Before |
| 6/4/1985 | SAN | Sutcliffe | Activated from Injured List | | | Before |
| 6/6/1985 | RIN | Bochy | Promoted to active roster | | | Before |
| 6/6/1985 | RIN | Davis,Ma | Demoted to reserve roster | | | Before |
| 6/6/1985 | RIN | Laudner | Demoted to reserve roster | | | Before |
| 6/6/1985 | RIN | McGaffigan | Promoted to active roster | | | Before |
| 6/9/1985 | RIN | Phelps | Demoted to reserve roster | | | Before |
| 6/11/1985 | ROC | Guerrero | Activated from Injured List | | | Before |
| 6/11/1985 | ROC | Washington,UL | Demoted to reserve roster | | | Before |
| 6/11/1985 | TWP | Cabell | Promoted to active roster | | | Before |
| 6/11/1985 | TWP | Cey | Placed on Injured List | | 6/10/1985 | Before |
| 6/12/1985 | HNT | Hurst | Placed on Injured List | | 6/11/1985 | Before |
| 6/12/1985 | HNT | Trout | Promoted to active roster | | | Before |
| 6/13/1985 | ROC | Carlton | Promoted to active roster | | | Before |
| 6/13/1985 | ROC | Hoyt | Placed on Injured List | | 6/12/1985 | Before |
| 6/15/1985 | AVI | Carter,J | Activated from Injured List | | | Before |
| 6/15/1985 | AVI | Cowens | Demoted to reserve roster | | | Before |
| 6/16/1985 | RIN | Deer | Promoted to active roster | | | Before |
| 6/16/1985 | RIN | Mazzilli | Demoted to reserve roster | | | Before |
| 6/16/1985 | RIN | Strawberry | Promoted to active roster | | | Before |
| 6/16/1985 | RIN | Tabler | Demoted to reserve roster | | | Before |
| 6/19/1985 | QME | Clancy | Placed on Injured List | | 6/17/1985 | Before |
| 6/19/1985 | QME | Palmer | Promoted to active roster | | | Before |
| 6/21/1985 | RIN | Coles | Promoted to active roster | | | Before |
| 6/21/1985 | RIN | Jacoby | Demoted to reserve roster | | | Before |
| 6/24/1985 | QME | Kearney | Promoted to active roster | | | Before |
| 6/24/1985 | QME | Puhl | Demoted to reserve roster | | | Before |
| 6/24/1985 | RIN | Murphy,R | Promoted to active roster | | | Before |
| 6/24/1985 | RIN | Thompson,R | Demoted to reserve roster | | | Before |
| 6/24/1985 | SOP | O'Neal | Promoted to active roster | | | Before |
| 6/24/1985 | SOP | Welch | Demoted to reserve roster | | | Before |
| 6/27/1985 | HNT | Hurst | Activated from Injured List | | | Before |
| 6/27/1985 | HNT | Trout | Demoted to reserve roster | | | Before |
| 6/27/1985 | QME | Filson | Promoted to active roster | | | Before |
| 6/27/1985 | QME | Guzman | Demoted to reserve roster | | | Before |
| 6/28/1985 | QME | Kearney | Demoted to reserve roster | | | Before |
| 6/28/1985 | QME | Puhl | Promoted to active roster | | | Before |
| 6/28/1985 | ROC | Carlton | Demoted to reserve roster | | | Before |
| 6/28/1985 | ROC | Hoyt | Activated from Injured List | | | Before |
| 6/28/1985 | ROC | Scott,D | Promoted to active roster | | | Before |
| 6/28/1985 | ROC | Tettleton | Demoted to reserve roster | | | Before |
| 7/2/1985 | RIN | Farr | Promoted to active roster | | | Before |
| 7/2/1985 | RIN | Murphy,R | Demoted to reserve roster | | | Before |
| 7/5/1985 | QME | Kearney | Promoted to active roster | | | Before |
| 7/5/1985 | QME | Perconte | Promoted to active roster | | | Before |
| 7/5/1985 | QME | Puhl | Demoted to reserve roster | | | Before |
| 7/5/1985 | QME | Ready | Demoted to reserve roster | | | Before |
| 7/6/1985 | QME | Kearney | Demoted to reserve roster | | | Before |
| 7/6/1985 | QME | Puhl | Promoted to active roster | | | Before |