Org pitching register -- EIGL
Regular season -- as of 9/30/2007
| Primary |
| Name | Team | P | Age | ERA | W | L | S | G | GS | CG | SHO | INN | H | R | ER | BB | K | HR | GDP |
| David Aardsma | CIO | mr | 25 | 8.60 | 0 | 5 | 1 | 25 | 0 | 0 | 0 | 30.1 | 47 | 30 | 29 | 22 | 35 | 3 | 2 |
| Jeremy Accardo | GAR | cl | 25 | 2.50 | 7 | 3 | 3 | 57 | 0 | 0 | 0 | 72.0 | 50 | 22 | 20 | 19 | 62 | 4 | 3 |
| Manny Acosta | BAR | mr | 26 | 0.00 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 4.0 | 0 | 0 | 0 | 2 | 2 | 0 | 1 |
| Jeremy Affeldt* | RYS | mr | 28 | 4.05 | 4 | 5 | 1 | 38 | 0 | 0 | 0 | 60.0 | 43 | 29 | 27 | 29 | 44 | 5 | 7 |
| Jonathan Albaladejo | GAR | mr | 24 | 0.00 | 0 | 0 | 1 | 9 | 0 | 0 | 0 | 14.2 | 7 | 3 | 0 | 2 | 8 | 1 | 1 |
| Matt Albers | RYS | sp | 24 | 5.91 | 4 | 7 | 1 | 28 | 15 | 0 | 0 | 105.0 | 120 | 76 | 69 | 48 | 66 | 19 | 4 |
| Tony Armas | FDH | mr | 29 | 4.24 | 3 | 2 | 2 | 24 | 6 | 0 | 0 | 51.0 | 52 | 25 | 24 | 16 | 35 | 8 | 1 |
| Bronson Arroyo | PHI | sp | 30 | 5.75 | 11 | 14 | 0 | 36 | 33 | 1 | 1 | 189.1 | 229 | 128 | 121 | 57 | 155 | 24 | 8 |
| Scott Atchison | ATM | mr | 31 | 2.28 | 1 | 3 | 7 | 22 | 0 | 0 | 0 | 27.2 | 26 | 7 | 7 | 7 | 35 | 4 | 0 |
| Luis Ayala | RMO | mr | 29 | 4.63 | 2 | 1 | 0 | 28 | 0 | 0 | 0 | 35.0 | 39 | 18 | 18 | 13 | 24 | 4 | 0 |
| Brandon Backe | BAR | sp | 29 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
| Mike Bacsik* | BRK | sp | 29 | 11.51 | 1 | 4 | 0 | 7 | 5 | 0 | 0 | 22.2 | 44 | 30 | 29 | 7 | 5 | 9 | 0 |
| Cha Seung Baek | HAR | sp | 27 | 4.77 | 6 | 1 | 0 | 14 | 14 | 0 | 0 | 83.0 | 88 | 44 | 44 | 14 | 50 | 9 | 4 |
| Danys Baez | CTW | mr | 29 | 4.64 | 1 | 2 | 3 | 36 | 0 | 0 | 0 | 42.2 | 50 | 26 | 22 | 18 | 17 | 11 | 6 |
| Homer Bailey | FDH | sp | 21 | 4.95 | 2 | 3 | 0 | 7 | 7 | 0 | 0 | 43.2 | 37 | 26 | 24 | 25 | 24 | 2 | 8 |
| Scott Baker | BRK | sp | 25 | 2.91 | 6 | 4 | 0 | 21 | 17 | 1 | 1 | 117.1 | 116 | 47 | 38 | 42 | 89 | 10 | 13 |
| John Bale* | CEN | mr | 33 | 0.00 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 3.0 | 2 | 0 | 0 | 0 | 3 | 0 | 0 |
| Grant Balfour | BBG | mr | 29 | 3.14 | 1 | 2 | 3 | 32 | 0 | 0 | 0 | 28.2 | 28 | 11 | 10 | 12 | 38 | 0 | 1 |
| Brian Bannister | NEP | sp | 26 | 4.09 | 7 | 15 | 0 | 41 | 21 | 1 | 0 | 160.2 | 180 | 87 | 73 | 37 | 74 | 18 | 15 |
| Miguel Batista | PHI | sp | 36 | 3.46 | 9 | 4 | 0 | 24 | 17 | 0 | 0 | 114.1 | 120 | 52 | 44 | 47 | 71 | 10 | 10 |
| Yorman Bazardo | NYD | mr | 22 | 4.85 | 1 | 1 | 0 | 4 | 4 | 0 | 0 | 26.0 | 25 | 14 | 14 | 3 | 7 | 2 | 2 |
| Josh Beckett | SOI | sp | 27 | 3.36 | 14 | 5 | 0 | 30 | 30 | 2 | 0 | 198.0 | 185 | 78 | 74 | 25 | 196 | 25 | 12 |
| Erik Bedard* | BAR | sp | 28 | 2.96 | 15 | 3 | 0 | 29 | 29 | 3 | 3 | 197.2 | 153 | 66 | 65 | 50 | 235 | 23 | 13 |
| Joe Beimel* | SOI | mr | 30 | 2.57 | 2 | 1 | 2 | 12 | 0 | 0 | 0 | 7.0 | 7 | 2 | 2 | 2 | 4 | 1 | 0 |
| Matt Belisle | FDH | sp | 27 | 4.71 | 7 | 9 | 0 | 33 | 27 | 0 | 0 | 154.2 | 184 | 85 | 81 | 42 | 100 | 19 | 21 |
| Heath Bell | NYD | mr | 29 | 4.14 | 8 | 6 | 10 | 52 | 0 | 0 | 0 | 78.1 | 70 | 38 | 36 | 33 | 102 | 8 | 6 |
| Jeff Bennett | REN | sp | 27 | 11.45 | 0 | 1 | 0 | 11 | 0 | 0 | 0 | 11.0 | 19 | 14 | 14 | 9 | 17 | 6 | 0 |
| Joaquin Benoit | NEP | mr | 29 | 3.74 | 2 | 6 | 23 | 57 | 0 | 0 | 0 | 74.2 | 63 | 32 | 31 | 21 | 86 | 6 | 3 |
| Jason Bergmann | RYS | sp | 25 | 7.88 | 3 | 5 | 0 | 11 | 10 | 0 | 0 | 48.0 | 62 | 42 | 42 | 25 | 37 | 10 | 2 |
| Rafael Betancourt | BAR | mr | 32 | 1.31 | 6 | 1 | 30 | 61 | 0 | 0 | 0 | 82.2 | 49 | 12 | 12 | 8 | 79 | 5 | 2 |
| Chad Billingsley | RMO | mr | 22 | 4.22 | 8 | 4 | 0 | 36 | 22 | 0 | 0 | 145.0 | 144 | 72 | 68 | 66 | 146 | 22 | 5 |
| Nick Blackburn | REN | mr | 25 | 6.23 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 13.0 | 19 | 12 | 9 | 2 | 13 | 3 | 1 |
| Joe Blanton | HAR | sp | 26 | 3.30 | 17 | 7 | 0 | 34 | 34 | 3 | 3 | 220.2 | 230 | 87 | 81 | 29 | 135 | 15 | 20 |
| Jerry Blevins* | CTW | mr | 23 | 9.00 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.0 | 6 | 4 | 4 | 2 | 0 | 3 | 0 |
| Jeremy Bonderman | HAR | sp | 24 | 4.94 | 6 | 3 | 0 | 17 | 17 | 0 | 0 | 89.1 | 97 | 53 | 49 | 19 | 86 | 7 | 6 |
| Boof Bonser | CBB | sp | 25 | 7.64 | 1 | 4 | 0 | 8 | 7 | 0 | 0 | 35.1 | 52 | 30 | 30 | 19 | 25 | 8 | 2 |
| Joe Borowski | PHI | cl | 36 | 5.03 | 0 | 3 | 3 | 16 | 0 | 0 | 0 | 19.2 | 21 | 13 | 11 | 6 | 16 | 4 | 1 |
| Blaine Boyer | CBB | mr | 25 | 4.50 | 0 | 1 | 0 | 6 | 0 | 0 | 0 | 6.0 | 11 | 3 | 3 | 1 | 4 | 0 | 0 |
| Dallas Braden* | RYS | sp | 23 | 9.46 | 1 | 6 | 0 | 24 | 8 | 0 | 0 | 65.2 | 106 | 71 | 69 | 34 | 61 | 12 | 2 |
| Chad Bradford | CEN | mr | 32 | 2.23 | 1 | 1 | 1 | 30 | 0 | 0 | 0 | 48.1 | 47 | 12 | 12 | 6 | 21 | 2 | 2 |
| Bill Bray* | FDH | mr | 24 | 1.32 | 1 | 1 | 3 | 11 | 0 | 0 | 0 | 13.2 | 11 | 2 | 2 | 5 | 17 | 1 | 1 |
| Chris Britton | BAR | mr | 24 | 2.57 | 1 | 0 | 0 | 5 | 0 | 0 | 0 | 7.0 | 2 | 2 | 2 | 0 | 2 | 2 | 0 |
| Lance Broadway | NYD | mr | 23 | 0.00 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 13.0 | 9 | 2 | 0 | 6 | 16 | 0 | 2 |
| Doug Brocail | TEW | mr | 40 | 4.50 | 1 | 3 | 5 | 37 | 0 | 0 | 0 | 46.0 | 46 | 24 | 23 | 19 | 26 | 7 | 5 |
| Andrew Brown | HAR | mr | 26 | 2.78 | 2 | 0 | 0 | 14 | 0 | 0 | 0 | 22.2 | 20 | 7 | 7 | 6 | 28 | 3 | 3 |
| Jonathan Broxton | NYD | mr | 23 | 2.50 | 6 | 4 | 7 | 58 | 0 | 0 | 0 | 86.1 | 66 | 29 | 24 | 25 | 120 | 7 | 4 |
| Brian Bruney | BRK | mr | 25 | 5.29 | 0 | 7 | 1 | 45 | 0 | 0 | 0 | 51.0 | 40 | 36 | 30 | 50 | 39 | 9 | 5 |
| Clay Buchholz | RYS | sp | 22 | 2.01 | 1 | 1 | 0 | 4 | 3 | 1 | 1 | 22.1 | 13 | 7 | 5 | 11 | 17 | 1 | 3 |
| Taylor Buchholz | TEW | mr | 25 | 3.38 | 4 | 5 | 2 | 64 | 0 | 0 | 0 | 101.1 | 102 | 38 | 38 | 23 | 65 | 11 | 14 |
| Mark Buehrle* | RMO | sp | 28 | 4.09 | 14 | 10 | 0 | 32 | 32 | 1 | 0 | 204.2 | 206 | 99 | 93 | 56 | 123 | 25 | 25 |
| Jason Bulger | NEP | mr | 28 | 7.11 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 6.1 | 9 | 8 | 5 | 2 | 6 | 0 | 0 |
| A.J. Burnett | CIN | sp | 30 | 3.46 | 10 | 7 | 0 | 36 | 27 | 0 | 0 | 176.2 | 143 | 78 | 68 | 64 | 194 | 32 | 14 |
| Brian Burres* | BRK | mr | 26 | 5.49 | 0 | 3 | 0 | 11 | 6 | 0 | 0 | 39.1 | 46 | 25 | 24 | 19 | 33 | 4 | 4 |
| Jared Burton | SOI | mr | 26 | 6.00 | 1 | 0 | 2 | 8 | 0 | 0 | 0 | 6.0 | 7 | 4 | 4 | 4 | 6 | 0 | 0 |
| Dave Bush | NEP | sp | 27 | 4.28 | 6 | 9 | 0 | 30 | 30 | 1 | 0 | 181.0 | 203 | 99 | 86 | 46 | 138 | 19 | 13 |
| Paul Byrd | NEP | sp | 36 | 4.60 | 2 | 5 | 0 | 10 | 10 | 1 | 0 | 60.2 | 71 | 34 | 31 | 7 | 25 | 10 | 2 |
| Tim Byrdak* | CIN | mr | 33 | 2.94 | 2 | 1 | 3 | 34 | 0 | 0 | 0 | 52.0 | 38 | 21 | 17 | 22 | 60 | 5 | 2 |
| Daniel Cabrera | BBG | sp | 26 | 4.96 | 7 | 13 | 0 | 30 | 24 | 0 | 0 | 141.2 | 141 | 84 | 78 | 77 | 108 | 19 | 19 |
| Matt Cain | CEN | sp | 22 | 4.02 | 16 | 4 | 0 | 33 | 33 | 0 | 0 | 188.0 | 170 | 87 | 84 | 82 | 161 | 20 | 8 |
| Kiko Calero | CIO | mr | 32 | 6.03 | 2 | 1 | 1 | 30 | 0 | 0 | 0 | 37.1 | 46 | 28 | 25 | 17 | 22 | 4 | 0 |
| Kevin Cameron | REN | mr | 27 | 3.45 | 5 | 1 | 1 | 33 | 0 | 0 | 0 | 44.1 | 50 | 18 | 17 | 22 | 38 | 1 | 5 |
| Shawn Camp | ATM | mr | 31 | 7.62 | 2 | 7 | 3 | 41 | 0 | 0 | 0 | 41.1 | 68 | 37 | 35 | 20 | 36 | 2 | 14 |
| Jorge Campillo | NEP | mr | 28 | 7.59 | 0 | 2 | 0 | 4 | 4 | 0 | 0 | 10.2 | 16 | 9 | 9 | 6 | 8 | 1 | 1 |
| Matt Capps | NYD | mr | 23 | 1.03 | 12 | 1 | 12 | 55 | 0 | 0 | 0 | 79.0 | 69 | 16 | 9 | 14 | 58 | 5 | 8 |
| Buddy Carlyle | REN | sp | 29 | 5.59 | 1 | 6 | 2 | 61 | 3 | 0 | 0 | 96.2 | 93 | 60 | 60 | 23 | 70 | 20 | 5 |
| Fausto Carmona | RMO | sp | 26 | 2.42 | 19 | 3 | 0 | 30 | 30 | 1 | 1 | 190.0 | 151 | 60 | 51 | 53 | 140 | 15 | 26 |
| Chris Carpenter | CIO | sp | 32 | 6.00 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 6.0 | 10 | 4 | 4 | 4 | 3 | 0 | 1 |
| Santiago Casilla | BBG | mr | 26 | 4.37 | 1 | 1 | 1 | 47 | 0 | 0 | 0 | 55.2 | 48 | 27 | 27 | 17 | 50 | 9 | 4 |
| Shawn Chacon | RMO | mr | 29 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| Joba Chamberlain | BAR | mr | 21 | 0.33 | 0 | 0 | 5 | 19 | 0 | 0 | 0 | 27.0 | 6 | 1 | 1 | 7 | 44 | 1 | 1 |
| Bruce Chen* | REN | mr | 30 | 8.44 | 0 | 1 | 0 | 9 | 0 | 0 | 0 | 10.2 | 14 | 10 | 10 | 8 | 9 | 2 | 1 |
| Matt Chico* | CTW | sp | 24 | 6.45 | 1 | 13 | 0 | 29 | 18 | 1 | 0 | 118.2 | 146 | 89 | 85 | 67 | 58 | 18 | 8 |
| Randy Choate* | RYS | mr | 31 | 18.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 2 | 2 | 2 | 1 | 0 | 0 | 0 |
| Roger Clemens | HAR | sp | 44 | 3.98 | 7 | 3 | 0 | 17 | 17 | 0 | 0 | 104.0 | 102 | 50 | 46 | 31 | 73 | 7 | 10 |
| Tyler Clippard | BRK | sp | 22 | 6.59 | 0 | 4 | 0 | 7 | 7 | 0 | 0 | 28.2 | 33 | 27 | 21 | 20 | 20 | 9 | 3 |
| Todd Coffey | RYS | mr | 26 | 9.14 | 1 | 3 | 1 | 30 | 0 | 0 | 0 | 42.1 | 69 | 50 | 43 | 20 | 25 | 13 | 6 |
| Jesus Colome | CIN | mr | 29 | 6.17 | 0 | 1 | 2 | 7 | 0 | 0 | 0 | 11.2 | 16 | 8 | 8 | 6 | 5 | 3 | 1 |
| Bartolo Colon | REN | sp | 34 | 7.63 | 9 | 7 | 1 | 66 | 3 | 0 | 0 | 94.1 | 153 | 83 | 80 | 27 | 69 | 26 | 5 |
| Clay Condrey | ATM | mr | 31 | 4.60 | 4 | 2 | 0 | 33 | 0 | 0 | 0 | 43.0 | 63 | 24 | 22 | 10 | 22 | 3 | 5 |
| Jose Contreras | NEP | sp | 35 | 6.28 | 7 | 20 | 0 | 35 | 34 | 1 | 0 | 197.2 | 261 | 150 | 138 | 62 | 123 | 21 | 19 |
| Aaron Cook | CIN | sp | 28 | 4.91 | 7 | 8 | 0 | 27 | 21 | 0 | 0 | 135.2 | 169 | 80 | 74 | 31 | 44 | 18 | 18 |
| Chad Cordero | SOI | cl | 25 | 3.43 | 8 | 2 | 3 | 57 | 0 | 0 | 0 | 78.2 | 73 | 32 | 30 | 24 | 68 | 6 | 4 |
| Francisco Cordero | CIN | cl | 32 | 3.26 | 2 | 1 | 8 | 39 | 0 | 0 | 0 | 60.2 | 53 | 22 | 22 | 21 | 84 | 5 | 0 |
| Lance Cormier | REN | sp | 26 | 8.57 | 0 | 4 | 2 | 18 | 4 | 0 | 0 | 42.0 | 61 | 42 | 40 | 16 | 19 | 10 | 6 |
| Manny Corpas | RMO | mr | 24 | 2.33 | 6 | 3 | 35 | 74 | 0 | 0 | 0 | 81.0 | 71 | 22 | 21 | 15 | 66 | 7 | 10 |
| Kevin Correia | ATM | mr | 26 | 3.38 | 2 | 2 | 0 | 7 | 7 | 0 | 0 | 45.1 | 48 | 17 | 17 | 11 | 40 | 4 | 3 |
| Neal Cotts* | FDH | mr | 27 | 9.68 | 0 | 1 | 6 | 19 | 0 | 0 | 0 | 17.2 | 24 | 21 | 19 | 9 | 6 | 0 | 3 |
| Jesse Crain | TEW | mr | 25 | 3.52 | 0 | 2 | 2 | 11 | 0 | 0 | 0 | 15.1 | 8 | 7 | 6 | 3 | 9 | 3 | 1 |
| Juan Cruz | HAR | mr | 28 | 2.74 | 3 | 2 | 4 | 50 | 0 | 0 | 0 | 65.2 | 42 | 21 | 20 | 23 | 98 | 7 | 2 |
| John Danks* | BRK | sp | 22 | 6.73 | 3 | 8 | 0 | 22 | 21 | 0 | 0 | 120.1 | 165 | 97 | 90 | 45 | 100 | 25 | 6 |
| Kyle Davies | CIO | sp | 23 | 9.13 | 3 | 10 | 0 | 26 | 16 | 0 | 0 | 67.0 | 91 | 74 | 68 | 45 | 58 | 12 | 1 |
| Doug Davis* | RYS | sp | 31 | 5.42 | 7 | 15 | 1 | 44 | 23 | 0 | 0 | 164.1 | 184 | 102 | 99 | 82 | 124 | 22 | 24 |
| Jorge De La Rosa* | CIO | sp | 26 | 6.77 | 6 | 14 | 2 | 92 | 8 | 0 | 0 | 133.0 | 168 | 108 | 100 | 57 | 88 | 26 | 14 |
| Manny Delcarmen | HAR | mr | 25 | 3.15 | 5 | 2 | 2 | 33 | 0 | 0 | 0 | 45.2 | 34 | 16 | 16 | 16 | 44 | 5 | 2 |
| Ryan Dempster | BAR | cl | 30 | 4.75 | 1 | 4 | 1 | 37 | 6 | 0 | 0 | 53.0 | 53 | 29 | 28 | 26 | 47 | 6 | 7 |
| Ross Detwiler* | HAR | mr | 21 | 0.00 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 2.1 | 0 | 0 | 0 | 0 | 2 | 0 | 0 |
| Joey Devine | ATM | mr | 23 | 3.38 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 8.0 | 11 | 3 | 3 | 4 | 9 | 0 | 0 |
| Lenny DiNardo* | RYS | sp | 27 | 6.14 | 4 | 8 | 3 | 36 | 15 | 0 | 0 | 121.2 | 149 | 89 | 83 | 66 | 49 | 22 | 20 |
| Brendan Donnelly | GAR | mr | 35 | 2.65 | 1 | 0 | 2 | 14 | 0 | 0 | 0 | 17.0 | 14 | 5 | 5 | 1 | 15 | 0 | 0 |
| Octavio Dotel | FDH | cl | 33 | 3.44 | 4 | 3 | 9 | 32 | 0 | 0 | 0 | 34.0 | 29 | 15 | 13 | 15 | 48 | 5 | 2 |
| Scott Downs* | SOI | mr | 31 | 3.86 | 5 | 2 | 8 | 60 | 0 | 0 | 0 | 56.0 | 51 | 24 | 24 | 30 | 51 | 5 | 4 |
| Justin Duchscherer | BAR | mr | 29 | 3.52 | 1 | 2 | 0 | 12 | 2 | 0 | 0 | 15.1 | 14 | 6 | 6 | 6 | 13 | 2 | 1 |
| Zach Duke* | CTW | sp | 24 | 7.23 | 5 | 11 | 0 | 21 | 20 | 0 | 0 | 107.0 | 164 | 91 | 86 | 42 | 43 | 16 | 17 |
| Chad Durbin | RYS | sp | 29 | 4.34 | 6 | 6 | 0 | 25 | 17 | 0 | 0 | 112.0 | 117 | 59 | 54 | 43 | 61 | 14 | 7 |
| J.D. Durbin | BRK | sp | 25 | 7.14 | 1 | 6 | 0 | 10 | 9 | 0 | 0 | 46.2 | 59 | 42 | 37 | 30 | 27 | 5 | 3 |
| Adam Eaton | CIO | sp | 29 | 7.93 | 2 | 13 | 0 | 42 | 20 | 0 | 0 | 109.0 | 131 | 105 | 96 | 76 | 67 | 19 | 5 |
| Scott Elarton | CIO | sp | 31 | 7.54 | 1 | 4 | 0 | 17 | 6 | 0 | 0 | 37.0 | 57 | 37 | 31 | 25 | 12 | 6 | 1 |
| Alan Embree* | CBB | cl | 37 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 |
| Kelvim Escobar | GAR | sp | 31 | 4.15 | 15 | 7 | 0 | 31 | 30 | 2 | 2 | 195.0 | 185 | 104 | 90 | 67 | 148 | 23 | 23 |
| Scott Feldman | BBG | mr | 24 | 6.64 | 1 | 1 | 2 | 36 | 0 | 0 | 0 | 40.2 | 47 | 31 | 30 | 32 | 27 | 6 | 4 |
| Pedro Feliciano* | SOI | mr | 30 | 3.63 | 1 | 0 | 1 | 21 | 0 | 0 | 0 | 22.1 | 23 | 10 | 9 | 15 | 19 | 1 | 3 |
| Gavin Floyd | CIN | sp | 24 | 4.31 | 9 | 1 | 0 | 26 | 6 | 0 | 0 | 71.0 | 73 | 35 | 34 | 19 | 52 | 15 | 10 |
| Josh Fogg | BBG | sp | 30 | 5.30 | 3 | 7 | 0 | 21 | 17 | 1 | 1 | 91.2 | 107 | 64 | 54 | 33 | 48 | 9 | 4 |
| Casey Fossum* | CTW | mr | 29 | 7.29 | 0 | 9 | 0 | 21 | 14 | 0 | 0 | 84.0 | 107 | 69 | 68 | 28 | 65 | 20 | 12 |
| Jeff Francis* | GAR | sp | 26 | 5.36 | 14 | 9 | 0 | 34 | 34 | 1 | 0 | 201.2 | 243 | 123 | 120 | 68 | 152 | 17 | 22 |
| Frank Francisco | NEP | mr | 27 | 5.61 | 3 | 2 | 2 | 49 | 0 | 0 | 0 | 59.1 | 59 | 39 | 37 | 38 | 49 | 6 | 3 |
| Ryan Franklin | CBB | mr | 34 | 3.90 | 3 | 1 | 3 | 57 | 0 | 0 | 0 | 80.2 | 82 | 36 | 35 | 8 | 44 | 11 | 3 |
| Jason Frasor | RYS | mr | 29 | 4.35 | 3 | 4 | 6 | 53 | 0 | 0 | 0 | 51.2 | 57 | 31 | 25 | 23 | 60 | 6 | 2 |
| Brian Fuentes* | HAR | cl | 31 | 4.26 | 4 | 3 | 7 | 57 | 0 | 0 | 0 | 61.1 | 54 | 29 | 29 | 31 | 58 | 7 | 4 |
| Aaron Fultz* | PHI | mr | 33 | 3.50 | 2 | 0 | 0 | 12 | 0 | 0 | 0 | 18.0 | 13 | 7 | 7 | 7 | 11 | 1 | 1 |
| Kason Gabbard* | NYD | sp | 25 | 1.89 | 8 | 2 | 0 | 14 | 14 | 1 | 0 | 90.2 | 49 | 20 | 19 | 46 | 60 | 4 | 11 |
| Eric Gagne | CEN | cl | 31 | 4.56 | 0 | 1 | 0 | 18 | 0 | 0 | 0 | 25.2 | 26 | 14 | 13 | 8 | 23 | 1 | 1 |
| Armando Galarraga | NEP | mr | 25 | 4.00 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 9.0 | 6 | 5 | 4 | 9 | 8 | 3 | 0 |
| Yovani Gallardo | PHI | sp | 21 | 4.09 | 8 | 4 | 0 | 16 | 16 | 0 | 0 | 105.2 | 108 | 52 | 48 | 36 | 104 | 15 | 4 |
| Freddy Garcia | CTW | sp | 31 | 5.10 | 2 | 2 | 0 | 9 | 9 | 0 | 0 | 54.2 | 61 | 31 | 31 | 21 | 50 | 10 | 2 |
| Lee Gardner | PHI | mr | 32 | 2.14 | 3 | 3 | 5 | 58 | 0 | 0 | 0 | 67.1 | 62 | 18 | 16 | 21 | 42 | 4 | 2 |
| Jon Garland | BAR | sp | 27 | 3.74 | 15 | 8 | 0 | 30 | 26 | 2 | 1 | 173.1 | 166 | 75 | 72 | 37 | 108 | 15 | 10 |
| Matt Garza | TEW | sp | 23 | 6.10 | 4 | 3 | 0 | 11 | 11 | 0 | 0 | 62.0 | 77 | 42 | 42 | 40 | 55 | 8 | 7 |
| Chad Gaudin | ATM | sp | 24 | 3.66 | 3 | 3 | 0 | 13 | 8 | 0 | 0 | 51.2 | 52 | 24 | 21 | 17 | 37 | 6 | 4 |
| Geoff Geary | NEP | mr | 30 | 4.48 | 4 | 2 | 0 | 50 | 0 | 0 | 0 | 62.1 | 75 | 36 | 31 | 22 | 34 | 9 | 10 |
| Justin Germano | TEW | sp | 24 | 4.31 | 5 | 4 | 0 | 14 | 14 | 0 | 0 | 77.1 | 82 | 39 | 37 | 25 | 38 | 13 | 11 |
| Dan Giese | CBB | mr | 30 | 4.09 | 0 | 2 | 0 | 6 | 0 | 0 | 0 | 11.0 | 11 | 5 | 5 | 3 | 10 | 2 | 0 |
| Tom Glavine* | BBG | sp | 41 | 6.60 | 7 | 14 | 0 | 37 | 31 | 1 | 0 | 165.0 | 232 | 133 | 121 | 64 | 73 | 22 | 22 |
| Mike Gonzalez* | BAR | mr | 29 | 10.80 | 0 | 1 | 0 | 5 | 0 | 0 | 0 | 5.0 | 5 | 6 | 6 | 6 | 5 | 1 | 1 |
| Tom Gordon | REN | mr | 39 | 5.13 | 6 | 5 | 12 | 35 | 0 | 0 | 0 | 40.1 | 46 | 25 | 23 | 18 | 35 | 8 | 3 |
| Tom Gorzelanny* | GAR | sp | 24 | 4.30 | 12 | 4 | 0 | 19 | 19 | 2 | 1 | 121.1 | 131 | 65 | 58 | 45 | 72 | 14 | 9 |
| John Grabow* | RYS | mr | 28 | 5.57 | 3 | 1 | 3 | 29 | 0 | 0 | 0 | 42.0 | 56 | 26 | 26 | 11 | 27 | 6 | 0 |
| Sean Green | ATM | mr | 28 | 5.06 | 0 | 2 | 1 | 21 | 0 | 0 | 0 | 26.2 | 30 | 16 | 15 | 10 | 14 | 3 | 6 |
| Kevin Gregg | RYS | cl | 29 | 5.92 | 2 | 5 | 0 | 45 | 6 | 0 | 0 | 59.1 | 60 | 44 | 39 | 42 | 60 | 10 | 6 |
| Zack Greinke | ATM | mr | 23 | 5.79 | 4 | 12 | 1 | 31 | 17 | 0 | 0 | 115.0 | 139 | 78 | 74 | 31 | 98 | 22 | 16 |
| Jason Grilli | ATM | mr | 30 | 4.08 | 3 | 5 | 4 | 49 | 0 | 0 | 0 | 68.1 | 72 | 33 | 31 | 26 | 54 | 7 | 4 |
| Eddie Guardado* | CTW | mr | 36 | 7.94 | 0 | 1 | 0 | 8 | 0 | 0 | 0 | 11.1 | 18 | 10 | 10 | 2 | 6 | 4 | 0 |
| Matt Guerrier | BAR | mr | 28 | 3.43 | 7 | 5 | 2 | 75 | 0 | 0 | 0 | 94.1 | 75 | 40 | 36 | 16 | 64 | 16 | 8 |
| Jeremy Guthrie | BAR | sp | 28 | 3.57 | 17 | 5 | 0 | 28 | 28 | 2 | 2 | 174.0 | 163 | 73 | 69 | 38 | 112 | 15 | 16 |
| Angel Guzman | CIO | mr | 25 | 4.70 | 0 | 2 | 0 | 10 | 1 | 0 | 0 | 23.0 | 24 | 12 | 12 | 13 | 21 | 1 | 2 |
| Roy Halladay | PHI | sp | 30 | 4.76 | 13 | 13 | 0 | 34 | 33 | 3 | 0 | 221.0 | 260 | 129 | 117 | 49 | 163 | 26 | 35 |
| Cole Hamels* | FDH | sp | 23 | 4.07 | 6 | 11 | 0 | 24 | 23 | 1 | 1 | 150.1 | 138 | 71 | 68 | 32 | 141 | 17 | 10 |
| Jason Hammel | REN | sp | 24 | 7.79 | 2 | 11 | 0 | 30 | 13 | 0 | 0 | 82.0 | 114 | 72 | 71 | 34 | 70 | 21 | 7 |
| Justin Hampson* | BAR | mr | 27 | 3.33 | 5 | 1 | 0 | 44 | 0 | 0 | 0 | 48.2 | 56 | 21 | 18 | 21 | 33 | 1 | 6 |
| Joel Hanrahan | BBG | sp | 25 | 10.13 | 2 | 7 | 0 | 16 | 10 | 0 | 0 | 48.0 | 72 | 56 | 54 | 34 | 38 | 16 | 2 |
| J.A. Happ* | RYS | sp | 24 | 14.29 | 0 | 1 | 0 | 2 | 1 | 0 | 0 | 5.2 | 12 | 9 | 9 | 4 | 1 | 3 | 2 |
| Aaron Harang | CBB | sp | 29 | 3.37 | 14 | 10 | 0 | 34 | 34 | 2 | 0 | 237.2 | 226 | 94 | 89 | 54 | 256 | 23 | 15 |
| Rich Harden | BRK | sp | 25 | 5.06 | 1 | 2 | 0 | 6 | 3 | 0 | 0 | 21.1 | 23 | 14 | 12 | 13 | 20 | 4 | 2 |
| Dan Haren | CIO | sp | 26 | 3.50 | 3 | 13 | 1 | 42 | 34 | 0 | 0 | 180.0 | 182 | 87 | 70 | 32 | 168 | 16 | 11 |
| LaTroy Hawkins | RMO | mr | 34 | 4.45 | 5 | 2 | 1 | 40 | 0 | 0 | 0 | 54.2 | 62 | 28 | 27 | 15 | 28 | 8 | 11 |
| Aaron Heilman | GAR | mr | 28 | 10.03 | 1 | 1 | 0 | 10 | 0 | 0 | 0 | 11.2 | 23 | 15 | 13 | 5 | 9 | 2 | 0 |
| Mark Hendrickson* | NYD | mr | 33 | 4.06 | 3 | 3 | 0 | 8 | 8 | 2 | 1 | 44.1 | 39 | 20 | 20 | 13 | 26 | 4 | 5 |
| Brad Hennessey | CIN | cl | 27 | 3.00 | 2 | 0 | 1 | 10 | 0 | 0 | 0 | 12.0 | 9 | 4 | 4 | 6 | 6 | 2 | 2 |
| Clay Hensley | TEW | sp | 27 | 7.88 | 1 | 5 | 0 | 9 | 9 | 0 | 0 | 37.2 | 57 | 37 | 33 | 28 | 31 | 6 | 3 |
| Matt Herges | CBB | mr | 37 | 2.19 | 2 | 2 | 23 | 43 | 0 | 0 | 0 | 49.1 | 40 | 17 | 12 | 11 | 26 | 2 | 3 |
| Felix Hernandez | CBB | sp | 21 | 4.45 | 7 | 14 | 0 | 31 | 31 | 1 | 0 | 188.0 | 209 | 101 | 93 | 52 | 155 | 25 | 24 |
| Livan Hernandez | FDH | sp | 32 | 7.05 | 2 | 9 | 0 | 15 | 12 | 1 | 0 | 67.2 | 96 | 56 | 53 | 27 | 29 | 10 | 9 |
| Orlando Hernandez | NYD | sp | 37 | 3.69 | 13 | 5 | 0 | 27 | 27 | 0 | 0 | 158.1 | 114 | 67 | 65 | 74 | 155 | 22 | 15 |
| Rich Hill* | SOI | sp | 27 | 4.21 | 16 | 6 | 0 | 29 | 29 | 0 | 0 | 171.0 | 152 | 96 | 80 | 74 | 166 | 21 | 14 |
| Shawn Hill | RMO | sp | 26 | 3.77 | 2 | 4 | 3 | 52 | 2 | 0 | 0 | 71.2 | 76 | 30 | 30 | 26 | 43 | 8 | 8 |
| Jason Hirsh | HAR | sp | 25 | 4.94 | 2 | 0 | 0 | 9 | 9 | 0 | 0 | 47.1 | 45 | 28 | 26 | 17 | 33 | 9 | 4 |
| Luke Hochevar | HAR | mr | 23 | 2.70 | 2 | 0 | 0 | 2 | 2 | 0 | 0 | 13.1 | 16 | 4 | 4 | 3 | 0 | 0 | 2 |
| Trevor Hoffman | GAR | cl | 39 | 1.97 | 6 | 4 | 10 | 48 | 0 | 0 | 0 | 64.0 | 47 | 15 | 14 | 12 | 50 | 3 | 1 |
| J.P. Howell* | CIO | sp | 24 | 4.22 | 4 | 7 | 5 | 35 | 3 | 0 | 0 | 53.1 | 61 | 25 | 25 | 19 | 53 | 11 | 0 |
| Bob Howry | GAR | mr | 33 | 7.27 | 1 | 1 | 1 | 13 | 0 | 0 | 0 | 17.1 | 21 | 14 | 14 | 4 | 14 | 5 | 1 |
| Tim Hudson | SOI | sp | 31 | 3.55 | 17 | 6 | 0 | 34 | 34 | 2 | 0 | 210.1 | 211 | 95 | 83 | 56 | 116 | 12 | 28 |
| Phil Hughes | NYD | sp | 21 | 3.04 | 8 | 2 | 0 | 14 | 14 | 1 | 1 | 80.0 | 60 | 35 | 27 | 27 | 57 | 13 | 8 |
| Philip Humber | BBG | mr | 24 | 7.71 | 0 | 1 | 0 | 3 | 1 | 0 | 0 | 9.1 | 13 | 8 | 8 | 2 | 1 | 1 | 0 |
| Jason Isringhausen | CEN | cl | 34 | 2.85 | 2 | 1 | 2 | 53 | 0 | 0 | 0 | 66.1 | 40 | 22 | 21 | 26 | 54 | 8 | 9 |
| Edwin Jackson | REN | sp | 23 | 4.67 | 4 | 9 | 0 | 26 | 25 | 1 | 1 | 138.2 | 140 | 76 | 72 | 61 | 100 | 19 | 10 |
| Chuck James* | FDH | sp | 25 | 3.54 | 1 | 4 | 1 | 17 | 5 | 0 | 0 | 48.1 | 45 | 21 | 19 | 17 | 32 | 8 | 2 |
| Casey Janssen | TEW | mr | 25 | 3.91 | 2 | 1 | 3 | 60 | 0 | 0 | 0 | 73.2 | 71 | 34 | 32 | 20 | 40 | 5 | 6 |
| Bobby Jenks | TEW | cl | 26 | 1.28 | 8 | 1 | 16 | 55 | 0 | 0 | 0 | 70.1 | 57 | 10 | 10 | 5 | 59 | 1 | 5 |
| Jason Jennings | BRK | sp | 28 | 5.08 | 1 | 9 | 0 | 12 | 12 | 0 | 0 | 67.1 | 77 | 41 | 38 | 28 | 48 | 9 | 6 |
| Ubaldo Jimenez | CIO | sp | 23 | 5.97 | 3 | 0 | 0 | 24 | 7 | 0 | 0 | 60.1 | 66 | 41 | 40 | 37 | 54 | 6 | 8 |
| Jim Johnson | TEW | mr | 24 | 189.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.1 | 6 | 7 | 7 | 2 | 0 | 0 | 0 |
| Josh Johnson | BBG | sp | 23 | 8.36 | 1 | 1 | 0 | 3 | 3 | 0 | 0 | 14.0 | 23 | 13 | 13 | 5 | 13 | 2 | 2 |
| Randy Johnson* | GAR | sp | 43 | 4.92 | 5 | 2 | 0 | 11 | 8 | 0 | 0 | 56.2 | 56 | 31 | 31 | 9 | 68 | 15 | 4 |
| Todd Jones | CTW | cl | 39 | 3.92 | 5 | 2 | 0 | 28 | 0 | 0 | 0 | 41.1 | 38 | 19 | 18 | 13 | 14 | 2 | 10 |
| Jair Jurrjens | NEP | sp | 21 | 2.67 | 2 | 0 | 0 | 4 | 4 | 0 | 0 | 27.0 | 22 | 9 | 8 | 12 | 14 | 3 | 4 |
| Jeff Karstens | FDH | mr | 24 | 16.88 | 0 | 3 | 0 | 13 | 1 | 0 | 0 | 13.1 | 29 | 31 | 25 | 12 | 13 | 6 | 0 |
| Scott Kazmir* | HAR | sp | 23 | 3.67 | 18 | 6 | 0 | 34 | 34 | 0 | 0 | 198.2 | 185 | 91 | 81 | 90 | 231 | 20 | 10 |
| Kyle Kendrick | CIN | sp | 22 | 3.58 | 6 | 5 | 0 | 23 | 20 | 0 | 0 | 120.2 | 112 | 52 | 48 | 29 | 43 | 14 | 21 |
| Ian Kennedy | BBG | sp | 22 | 3.93 | 1 | 1 | 0 | 4 | 3 | 0 | 0 | 18.1 | 10 | 8 | 8 | 7 | 24 | 1 | 0 |
| Byung-Hyun Kim | CTW | sp | 28 | 5.13 | 3 | 6 | 1 | 35 | 6 | 0 | 0 | 80.2 | 90 | 49 | 46 | 34 | 69 | 14 | 11 |
| Hong-Chih Kuo* | NYD | sp | 25 | 1.69 | 2 | 1 | 6 | 29 | 1 | 0 | 0 | 37.1 | 35 | 7 | 7 | 11 | 34 | 3 | 4 |
| John Lackey | GAR | sp | 28 | 3.35 | 17 | 9 | 0 | 33 | 33 | 1 | 1 | 228.1 | 200 | 95 | 85 | 43 | 203 | 28 | 27 |
| Aaron Laffey* | NYD | sp | 22 | 3.39 | 4 | 3 | 0 | 9 | 9 | 0 | 0 | 58.1 | 56 | 22 | 22 | 8 | 27 | 2 | 9 |
| John Lannan* | RYS | sp | 22 | 6.23 | 1 | 3 | 0 | 4 | 4 | 1 | 1 | 26.0 | 36 | 18 | 18 | 14 | 7 | 4 | 3 |
| Brandon League | ATM | mr | 24 | 11.00 | 0 | 1 | 0 | 8 | 0 | 0 | 0 | 9.0 | 21 | 11 | 11 | 5 | 9 | 0 | 1 |
| Cliff Lee* | BRK | sp | 28 | 6.56 | 2 | 7 | 0 | 17 | 14 | 0 | 0 | 82.1 | 96 | 62 | 60 | 33 | 63 | 23 | 5 |
| Jon Lester* | CIO | sp | 23 | 5.92 | 1 | 1 | 1 | 27 | 3 | 0 | 0 | 48.2 | 54 | 33 | 32 | 24 | 47 | 11 | 2 |
| Colby Lewis | BBG | mr | 27 | 7.30 | 2 | 3 | 0 | 11 | 5 | 0 | 0 | 37.0 | 65 | 31 | 30 | 16 | 30 | 7 | 4 |
| Jensen Lewis | BAR | mr | 23 | 0.00 | 1 | 0 | 0 | 3 | 0 | 0 | 0 | 4.2 | 3 | 0 | 0 | 1 | 6 | 0 | 0 |
| Brad Lidge | BRK | cl | 30 | 8.63 | 3 | 6 | 2 | 51 | 0 | 0 | 0 | 48.0 | 60 | 50 | 46 | 21 | 70 | 11 | 2 |
| Ted Lilly* | CIN | sp | 31 | 4.89 | 9 | 12 | 0 | 33 | 31 | 1 | 0 | 167.1 | 159 | 99 | 91 | 48 | 169 | 43 | 6 |
| Tim Lincecum | NYD | sp | 23 | 3.79 | 8 | 7 | 0 | 26 | 26 | 0 | 0 | 154.1 | 130 | 70 | 65 | 70 | 155 | 15 | 9 |
| Matt Lindstrom | PHI | mr | 27 | 2.36 | 2 | 1 | 7 | 64 | 0 | 0 | 0 | 72.1 | 48 | 21 | 19 | 26 | 54 | 3 | 10 |
| Scott Linebrink | ATM | mr | 30 | 6.06 | 3 | 5 | 5 | 47 | 0 | 0 | 0 | 52.0 | 76 | 39 | 35 | 23 | 32 | 11 | 5 |
| Jesse Litsch | REN | sp | 22 | 3.93 | 4 | 6 | 0 | 19 | 14 | 2 | 0 | 100.2 | 101 | 47 | 44 | 33 | 55 | 14 | 15 |
| Wes Littleton | BAR | mr | 24 | 4.46 | 5 | 1 | 0 | 23 | 0 | 0 | 0 | 40.1 | 34 | 24 | 20 | 9 | 21 | 5 | 1 |
| Bobby Livingston* | PHI | sp | 24 | 10.38 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 4.1 | 10 | 5 | 5 | 1 | 3 | 1 | 0 |
| Kameron Loe | FDH | sp | 25 | 3.84 | 4 | 6 | 1 | 30 | 20 | 1 | 1 | 129.0 | 130 | 66 | 55 | 41 | 77 | 11 | 17 |
| Kyle Lohse | FDH | sp | 28 | 4.42 | 4 | 14 | 0 | 29 | 27 | 0 | 0 | 156.2 | 171 | 93 | 77 | 54 | 98 | 13 | 14 |
| Braden Looper | CBB | sp | 32 | 4.36 | 13 | 9 | 0 | 28 | 28 | 2 | 2 | 177.2 | 184 | 101 | 86 | 58 | 87 | 21 | 12 |
| Javier Lopez* | RYS | mr | 29 | 3.47 | 4 | 1 | 4 | 37 | 0 | 0 | 0 | 36.1 | 20 | 16 | 14 | 16 | 20 | 2 | 7 |
| Rodrigo Lopez | CBB | sp | 31 | 4.71 | 4 | 5 | 0 | 14 | 14 | 0 | 0 | 84.0 | 101 | 47 | 44 | 22 | 46 | 13 | 7 |
| Derek Lowe | TEW | sp | 34 | 4.08 | 14 | 8 | 0 | 33 | 33 | 1 | 1 | 205.0 | 204 | 102 | 93 | 87 | 156 | 21 | 34 |
| Mark Lowe | HAR | mr | 24 | 0.00 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 4.0 | 3 | 0 | 0 | 1 | 4 | 0 | 0 |
| Brandon Lyon | FDH | mr | 27 | 3.77 | 1 | 5 | 3 | 47 | 0 | 0 | 0 | 62.0 | 69 | 31 | 26 | 19 | 31 | 3 | 3 |
| Greg Maddux | CBB | sp | 41 | 5.18 | 10 | 14 | 0 | 34 | 34 | 0 | 0 | 196.1 | 244 | 119 | 113 | 24 | 115 | 12 | 17 |
| Ryan Madson | BBG | mr | 26 | 4.36 | 1 | 3 | 2 | 39 | 0 | 0 | 0 | 53.2 | 61 | 29 | 26 | 15 | 36 | 3 | 2 |
| Ron Mahay* | NYD | mr | 36 | 3.48 | 4 | 5 | 8 | 45 | 0 | 0 | 0 | 62.0 | 44 | 27 | 24 | 49 | 44 | 5 | 12 |
| John Maine | TEW | sp | 26 | 5.35 | 10 | 11 | 0 | 33 | 33 | 1 | 0 | 180.0 | 176 | 113 | 107 | 69 | 168 | 37 | 11 |
| Shaun Marcum | PHI | sp | 25 | 4.59 | 6 | 8 | 0 | 27 | 26 | 0 | 0 | 147.0 | 146 | 78 | 75 | 49 | 113 | 28 | 14 |
| Carlos Marmol | SOI | mr | 24 | 2.92 | 3 | 1 | 13 | 61 | 0 | 0 | 0 | 74.0 | 47 | 24 | 24 | 36 | 103 | 4 | 3 |
| Mike Maroth* | CIO | sp | 29 | 10.01 | 1 | 15 | 3 | 78 | 10 | 0 | 0 | 113.1 | 191 | 130 | 126 | 62 | 55 | 33 | 12 |
| Jason Marquis | CIO | sp | 28 | 5.29 | 3 | 13 | 1 | 40 | 29 | 0 | 0 | 151.1 | 153 | 99 | 89 | 83 | 84 | 15 | 13 |
| Sean Marshall* | BBG | sp | 24 | 4.08 | 7 | 4 | 0 | 20 | 14 | 0 | 0 | 88.1 | 101 | 43 | 40 | 35 | 59 | 6 | 15 |
| Damaso Marte* | ATM | mr | 32 | 6.00 | 0 | 3 | 1 | 27 | 0 | 0 | 0 | 33.0 | 35 | 22 | 22 | 15 | 38 | 3 | 3 |
| Pedro Martinez | CEN | sp | 35 | 4.76 | 1 | 2 | 0 | 10 | 4 | 0 | 0 | 34.0 | 40 | 18 | 18 | 7 | 27 | 4 | 3 |
| Nick Masset | CIO | mr | 25 | 6.39 | 1 | 2 | 2 | 37 | 0 | 0 | 0 | 43.2 | 51 | 37 | 31 | 29 | 24 | 4 | 4 |
| Daisuke Matsuzaka | CEN | sp | 26 | 3.83 | 18 | 8 | 0 | 33 | 33 | 3 | 1 | 206.2 | 172 | 98 | 88 | 73 | 217 | 28 | 14 |
| Brandon McCarthy | BRK | sp | 23 | 5.84 | 7 | 8 | 0 | 43 | 12 | 0 | 0 | 103.1 | 124 | 76 | 67 | 47 | 69 | 17 | 9 |
| Dustin McGowan | NYD | sp | 25 | 2.60 | 16 | 3 | 0 | 29 | 29 | 0 | 0 | 194.0 | 142 | 59 | 56 | 47 | 163 | 15 | 11 |
| Gil Meche | RMO | sp | 28 | 5.15 | 3 | 5 | 0 | 10 | 10 | 0 | 0 | 57.2 | 56 | 38 | 33 | 25 | 49 | 8 | 6 |
| Luis Mendoza | GAR | sp | 23 | 2.84 | 1 | 1 | 2 | 9 | 0 | 0 | 0 | 19.0 | 17 | 7 | 6 | 3 | 11 | 1 | 3 |
| Cla Meredith | CBB | mr | 24 | 4.11 | 3 | 2 | 0 | 40 | 1 | 0 | 0 | 50.1 | 66 | 25 | 23 | 18 | 35 | 3 | 9 |
| Jose Mesa |   | mr | 41 | 5.09 | 6 | 1 | 3 | 49 | 0 | 0 | 0 | 53.0 | 58 | 31 | 30 | 20 | 24 | 6 | 3 |
| Dan Meyer* | BRK | sp | 25 | 5.49 | 0 | 1 | 2 | 14 | 0 | 0 | 0 | 19.2 | 24 | 14 | 12 | 6 | 11 | 2 | 1 |
| Andrew Miller* | BRK | sp | 22 | 7.75 | 1 | 13 | 14 | 42 | 3 | 0 | 0 | 65.0 | 85 | 61 | 56 | 47 | 58 | 12 | 5 |
| Justin Miller | CIN | mr | 29 | 3.30 | 5 | 1 | 5 | 34 | 0 | 0 | 0 | 57.1 | 49 | 22 | 21 | 18 | 65 | 8 | 4 |
| Trever Miller* | CIN | mr | 34 | 5.02 | 1 | 5 | 1 | 35 | 0 | 0 | 0 | 37.2 | 37 | 22 | 21 | 19 | 25 | 6 | 2 |
| Kevin Millwood | CTW | sp | 32 | 4.07 | 7 | 7 | 0 | 35 | 22 | 4 | 3 | 170.1 | 166 | 81 | 77 | 50 | 95 | 24 | 19 |
| Sergio Mitre | NYD | sp | 26 | 5.12 | 2 | 2 | 3 | 36 | 7 | 1 | 1 | 77.1 | 110 | 48 | 44 | 19 | 50 | 9 | 8 |
| Franklin Morales* | GAR | sp | 21 | 5.60 | 0 | 1 | 0 | 5 | 5 | 0 | 0 | 27.1 | 26 | 18 | 17 | 13 | 22 | 4 | 3 |
| Brandon Morrow | TEW | mr | 22 | 4.87 | 2 | 7 | 1 | 52 | 0 | 0 | 0 | 61.0 | 61 | 36 | 33 | 43 | 61 | 4 | 3 |
| Dustin Moseley | PHI | mr | 25 | 2.98 | 9 | 4 | 0 | 15 | 15 | 1 | 0 | 99.2 | 114 | 41 | 33 | 23 | 61 | 7 | 17 |
| Guillermo Mota | BRK | mr | 33 | 8.17 | 3 | 2 | 4 | 55 | 0 | 0 | 0 | 54.0 | 78 | 52 | 49 | 31 | 37 | 14 | 0 |
| Jamie Moyer* | REN | sp | 44 | 5.46 | 6 | 17 | 0 | 33 | 33 | 1 | 0 | 194.1 | 249 | 130 | 118 | 60 | 154 | 30 | 12 |
| Peter Moylan | RMO | mr | 28 | 6.33 | 2 | 8 | 2 | 64 | 0 | 0 | 0 | 75.1 | 91 | 55 | 53 | 18 | 55 | 12 | 11 |
| Edward Mujica | ATM | mr | 23 | 4.91 | 1 | 3 | 2 | 10 | 0 | 0 | 0 | 11.0 | 14 | 6 | 6 | 1 | 7 | 3 | 0 |
| Mike Mussina | PHI | sp | 38 | 6.18 | 4 | 7 | 0 | 22 | 21 | 0 | 0 | 118.0 | 162 | 88 | 81 | 23 | 96 | 22 | 11 |
| Brett Myers | PHI | cl | 26 | 4.13 | 3 | 2 | 1 | 53 | 0 | 0 | 0 | 61.0 | 57 | 30 | 28 | 29 | 79 | 8 | 2 |
| Joe Nathan | CEN | cl | 32 | 2.41 | 4 | 3 | 14 | 58 | 0 | 0 | 0 | 71.0 | 45 | 19 | 19 | 15 | 74 | 7 | 3 |
| Pat Neshek | NYD | mr | 26 | 1.88 | 7 | 3 | 12 | 46 | 0 | 0 | 0 | 71.2 | 33 | 16 | 15 | 20 | 83 | 10 | 4 |
| Ricky Nolasco | ATM | sp | 24 | 10.31 | 0 | 3 | 0 | 9 | 3 | 0 | 0 | 18.1 | 37 | 21 | 21 | 11 | 13 | 3 | 0 |
| Leo Nunez | ATM | mr | 23 | 4.54 | 0 | 1 | 0 | 20 | 0 | 0 | 0 | 35.2 | 31 | 20 | 18 | 9 | 26 | 9 | 3 |
| Eric O'Flaherty* | RYS | mr | 22 | 4.65 | 1 | 2 | 1 | 36 | 0 | 0 | 0 | 40.2 | 54 | 22 | 21 | 19 | 29 | 2 | 4 |
| Ross Ohlendorf | RYS | mr | 24 | 5.79 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 4.2 | 3 | 5 | 3 | 8 | 5 | 0 | 0 |
| Will Ohman* | NEP | mr | 29 | 4.08 | 1 | 1 | 1 | 32 | 0 | 0 | 0 | 39.2 | 44 | 21 | 18 | 14 | 32 | 1 | 2 |
| Hideki Okajima* | CBB | mr | 31 | 2.38 | 5 | 4 | 7 | 54 | 0 | 0 | 0 | 75.2 | 45 | 25 | 20 | 14 | 73 | 5 | 4 |
| Darren Oliver* | BBG | mr | 36 | 3.64 | 1 | 4 | 5 | 45 | 0 | 0 | 0 | 64.1 | 59 | 31 | 26 | 20 | 61 | 10 | 5 |
| Scott Olsen* | CIO | sp | 23 | 6.39 | 0 | 2 | 3 | 30 | 2 | 0 | 0 | 49.1 | 70 | 36 | 35 | 25 | 34 | 9 | 7 |
| Ramon Ortiz | FDH | mr | 34 | 5.80 | 3 | 5 | 2 | 65 | 0 | 0 | 0 | 111.2 | 133 | 78 | 72 | 24 | 64 | 20 | 8 |
| Roy Oswalt | CEN | sp | 29 | 3.84 | 19 | 6 | 0 | 34 | 33 | 3 | 2 | 213.1 | 217 | 98 | 91 | 52 | 162 | 15 | 18 |
| Akinori Otsuka | CEN | mr | 35 | 1.27 | 5 | 2 | 0 | 33 | 0 | 0 | 0 | 35.1 | 24 | 6 | 5 | 12 | 21 | 1 | 1 |
| Micah Owings | SOI | sp | 24 | 6.00 | 2 | 0 | 0 | 5 | 3 | 0 | 0 | 21.0 | 25 | 14 | 14 | 7 | 15 | 4 | 3 |
| Vicente Padilla | CIN | sp | 29 | 2.00 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 9.0 | 5 | 2 | 2 | 5 | 2 | 0 | 3 |
| Jonathan Papelbon | HAR | cl | 26 | 1.82 | 7 | 3 | 27 | 58 | 0 | 0 | 0 | 64.1 | 36 | 13 | 13 | 9 | 91 | 8 | 3 |
| Manny Parra* | NYD | mr | 24 | 5.60 | 0 | 0 | 0 | 6 | 6 | 0 | 0 | 27.1 | 35 | 17 | 17 | 21 | 24 | 1 | 3 |
| Troy Patton* | TEW | sp | 21 | 4.35 | 1 | 0 | 0 | 9 | 0 | 0 | 0 | 10.1 | 13 | 6 | 5 | 4 | 6 | 2 | 1 |
| Carl Pavano | NEP | sp | 31 | 2.93 | 2 | 1 | 1 | 8 | 1 | 0 | 0 | 15.1 | 13 | 5 | 5 | 3 | 6 | 3 | 2 |
| Jake Peavy | SOI | sp | 26 | 3.06 | 22 | 6 | 0 | 33 | 33 | 2 | 2 | 220.1 | 193 | 85 | 75 | 72 | 232 | 18 | 23 |
| Mike Pelfrey | REN | sp | 23 | 6.19 | 3 | 7 | 1 | 33 | 9 | 0 | 0 | 77.0 | 91 | 56 | 53 | 44 | 41 | 9 | 8 |
| Ramon Antonio Pena | GAR | mr | 25 | 3.56 | 1 | 1 | 5 | 38 | 0 | 0 | 0 | 55.2 | 52 | 25 | 22 | 16 | 50 | 7 | 7 |
| Brad Penny | RMO | sp | 29 | 3.97 | 11 | 10 | 0 | 31 | 31 | 2 | 2 | 185.2 | 210 | 97 | 82 | 65 | 128 | 8 | 19 |
| Joel Peralta | BBG | mr | 31 | 4.34 | 5 | 6 | 10 | 68 | 0 | 0 | 0 | 93.1 | 91 | 46 | 45 | 16 | 68 | 13 | 7 |
| Troy Percival | BAR | mr | 37 | 2.68 | 3 | 1 | 4 | 31 | 1 | 0 | 0 | 40.1 | 29 | 12 | 12 | 8 | 40 | 5 | 0 |
| Odalis Perez* | CIO | sp | 30 | 4.45 | 2 | 6 | 0 | 18 | 7 | 0 | 0 | 56.2 | 68 | 28 | 28 | 20 | 30 | 6 | 9 |
| Oliver Perez* | RMO | sp | 25 | 32.40 | 0 | 0 | 1 | 3 | 0 | 0 | 0 | 1.2 | 4 | 6 | 6 | 2 | 2 | 1 | 0 |
| Rafael Perez* | SOI | mr | 25 | 4.11 | 2 | 2 | 12 | 38 | 0 | 0 | 0 | 61.1 | 48 | 31 | 28 | 20 | 71 | 8 | 4 |
| Glen Perkins* | ATM | mr | 24 | 1.40 | 2 | 1 | 1 | 13 | 1 | 0 | 0 | 25.2 | 22 | 6 | 4 | 11 | 19 | 0 | 6 |
| Yusmeiro Petit | RYS | sp | 22 | 5.21 | 2 | 4 | 0 | 20 | 6 | 0 | 0 | 57.0 | 61 | 41 | 33 | 24 | 43 | 10 | 5 |
| Andy Pettitte* | HAR | sp | 35 | 5.97 | 9 | 13 | 0 | 34 | 33 | 1 | 0 | 176.1 | 239 | 126 | 117 | 52 | 108 | 17 | 20 |
| Joel Pineiro | BRK | mr | 28 | 4.72 | 2 | 3 | 2 | 65 | 1 | 0 | 0 | 74.1 | 82 | 41 | 39 | 31 | 52 | 11 | 8 |
| Scott Proctor | BBG | mr | 30 | 6.58 | 1 | 2 | 1 | 45 | 0 | 0 | 0 | 39.2 | 44 | 35 | 29 | 22 | 28 | 6 | 1 |
| J.J. Putz | HAR | cl | 30 | 1.32 | 5 | 1 | 8 | 57 | 0 | 0 | 0 | 75.0 | 36 | 12 | 11 | 16 | 89 | 7 | 9 |
| Chad Qualls | PHI | mr | 28 | 3.79 | 4 | 6 | 16 | 82 | 0 | 0 | 0 | 76.0 | 74 | 36 | 32 | 35 | 64 | 7 | 13 |
| Edwar Ramirez | TEW | mr | 26 | 3.86 | 0 | 0 | 1 | 3 | 0 | 0 | 0 | 2.1 | 1 | 1 | 1 | 1 | 2 | 1 | 0 |
| Horacio Ramirez* | CIO | sp | 27 | 6.33 | 3 | 6 | 0 | 43 | 12 | 0 | 0 | 101.0 | 121 | 74 | 71 | 57 | 41 | 15 | 18 |
| Ramon Ramirez | PHI | mr | 25 | 7.64 | 0 | 2 | 1 | 18 | 0 | 0 | 0 | 17.2 | 22 | 16 | 15 | 8 | 16 | 2 | 0 |
| Jon Rauch | CIN | mr | 28 | 3.04 | 6 | 3 | 9 | 51 | 0 | 0 | 0 | 77.0 | 61 | 28 | 26 | 17 | 50 | 6 | 9 |
| Chris Ray | NYD | cl | 25 | 3.05 | 0 | 0 | 0 | 13 | 0 | 0 | 0 | 20.2 | 11 | 7 | 7 | 8 | 15 | 2 | 3 |
| Tim Redding | CEN | sp | 29 | 1.08 | 2 | 0 | 1 | 3 | 1 | 0 | 0 | 8.1 | 6 | 1 | 1 | 2 | 4 | 0 | 2 |
| Al Reyes | CBB | cl | 37 | 3.70 | 6 | 4 | 5 | 55 | 0 | 0 | 0 | 65.2 | 49 | 28 | 27 | 19 | 84 | 14 | 0 |
| Anthony Reyes | FDH | sp | 25 | 3.70 | 1 | 2 | 0 | 9 | 6 | 0 | 0 | 41.1 | 35 | 18 | 17 | 17 | 32 | 5 | 1 |
| David Riske | CBB | mr | 30 | 3.77 | 2 | 4 | 1 | 28 | 0 | 0 | 0 | 31.0 | 28 | 13 | 13 | 8 | 32 | 4 | 0 |
| Mariano Rivera | CTW | cl | 37 | 2.67 | 2 | 7 | 26 | 50 | 0 | 0 | 0 | 60.2 | 46 | 18 | 18 | 12 | 55 | 5 | 4 |
| Saul Rivera | PHI | mr | 29 | 6.00 | 5 | 3 | 2 | 53 | 0 | 0 | 0 | 60.0 | 76 | 46 | 40 | 49 | 39 | 4 | 6 |
| Nate Robertson* |   | sp | 29 | 5.75 | 3 | 11 | 2 | 56 | 1 | 0 | 0 | 83.0 | 101 | 54 | 53 | 26 | 51 | 11 | 9 |
| Fernando Rodney | BBG | mr | 30 | 4.56 | 2 | 2 | 5 | 38 | 0 | 0 | 0 | 51.1 | 53 | 29 | 26 | 24 | 55 | 5 | 3 |
| Francisco Rodriguez |   | cl | 25 | 2.03 | 7 | 2 | 12 | 61 | 0 | 0 | 0 | 71.0 | 49 | 17 | 16 | 31 | 102 | 4 | 3 |
| Wandy Rodriguez* | ATM | sp | 28 | 5.24 | 5 | 11 | 0 | 26 | 26 | 0 | 0 | 144.1 | 168 | 90 | 84 | 57 | 127 | 23 | 13 |
| Kenny Rogers* | CBB | sp | 42 | 4.92 | 3 | 7 | 0 | 13 | 13 | 0 | 0 | 67.2 | 71 | 43 | 37 | 22 | 46 | 9 | 7 |
| J.C. Romero* | PHI | mr | 31 | 3.65 | 3 | 5 | 2 | 55 | 0 | 0 | 0 | 56.2 | 40 | 25 | 23 | 33 | 32 | 5 | 5 |
| Ryan Rowland-Smith* | NEP | mr | 24 | 3.82 | 3 | 1 | 0 | 21 | 0 | 0 | 0 | 30.2 | 36 | 13 | 13 | 12 | 35 | 4 | 4 |
| B.J. Ryan* | CTW | cl | 31 | 19.29 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 4.2 | 11 | 10 | 10 | 3 | 1 | 2 | 1 |
| Kirk Saarloos | REN | mr | 28 | 8.63 | 0 | 3 | 1 | 18 | 2 | 0 | 0 | 24.0 | 37 | 25 | 23 | 12 | 17 | 7 | 3 |
| C.C. Sabathia* | ATM | sp | 26 | 4.18 | 11 | 10 | 0 | 33 | 33 | 3 | 1 | 230.1 | 240 | 116 | 107 | 38 | 200 | 38 | 22 |
| Takashi Saito | GAR | cl | 37 | 2.98 | 3 | 3 | 26 | 49 | 0 | 0 | 0 | 60.1 | 42 | 21 | 20 | 22 | 67 | 12 | 2 |
| Chris Sampson | TEW | sp | 29 | 4.48 | 6 | 7 | 0 | 18 | 18 | 0 | 0 | 96.1 | 116 | 54 | 48 | 37 | 38 | 10 | 11 |
| Brian Sanches | BRK | mr | 28 | 7.13 | 1 | 1 | 1 | 17 | 0 | 0 | 0 | 17.2 | 16 | 14 | 14 | 13 | 12 | 8 | 2 |
| Anibal Sanchez | CIN | sp | 23 | 6.04 | 0 | 2 | 0 | 7 | 7 | 0 | 0 | 25.1 | 35 | 17 | 17 | 21 | 8 | 3 | 3 |
| Jonathan Sanchez* | RYS | mr | 24 | 5.72 | 0 | 3 | 2 | 20 | 7 | 0 | 0 | 50.1 | 65 | 34 | 32 | 33 | 60 | 7 | 6 |
| Ervin Santana | ATM | sp | 24 | 6.64 | 7 | 8 | 0 | 27 | 24 | 0 | 0 | 123.1 | 154 | 98 | 91 | 52 | 114 | 25 | 10 |
| Johan Santana* | GAR | sp | 28 | 4.56 | 20 | 6 | 0 | 34 | 33 | 0 | 0 | 213.1 | 190 | 113 | 108 | 43 | 232 | 47 | 10 |
| Dennis Sarfate | GAR | mr | 26 | 3.38 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.2 | 3 | 1 | 1 | 1 | 2 | 0 | 1 |
| Joe Saunders* | RMO | sp | 26 | 2.01 | 1 | 0 | 1 | 4 | 3 | 0 | 0 | 22.1 | 21 | 6 | 5 | 3 | 12 | 2 | 3 |
| Curt Schilling | CEN | sp | 40 | 3.69 | 13 | 7 | 0 | 26 | 26 | 3 | 2 | 168.1 | 149 | 74 | 69 | 23 | 130 | 26 | 5 |
| Chris Schroder | TEW | mr | 28 | 3.78 | 5 | 1 | 4 | 34 | 0 | 0 | 0 | 47.2 | 41 | 22 | 20 | 16 | 40 | 2 | 2 |
| Bobby Seay* | RYS | mr | 29 | 5.24 | 3 | 4 | 2 | 25 | 4 | 0 | 0 | 34.1 | 43 | 22 | 20 | 10 | 27 | 4 | 1 |
| Ben Sheets | TEW | sp | 28 | 4.49 | 8 | 11 | 0 | 24 | 24 | 3 | 1 | 152.1 | 149 | 84 | 76 | 38 | 133 | 31 | 6 |
| George Sherrill* | SOI | mr | 30 | 1.32 | 3 | 0 | 5 | 48 | 0 | 0 | 0 | 47.2 | 33 | 8 | 7 | 19 | 49 | 1 | 3 |
| James Shields | ATM | sp | 25 | 4.20 | 10 | 7 | 0 | 24 | 24 | 0 | 0 | 158.2 | 150 | 76 | 74 | 35 | 150 | 24 | 5 |
| Scot Shields | HAR | mr | 31 | 2.41 | 11 | 2 | 2 | 53 | 1 | 0 | 0 | 82.0 | 65 | 26 | 22 | 23 | 67 | 8 | 12 |
| Brian Shouse* | BRK | mr | 38 | 4.57 | 1 | 0 | 0 | 39 | 0 | 0 | 0 | 43.1 | 53 | 23 | 22 | 20 | 27 | 0 | 7 |
| Carlos Silva | TEW | sp | 28 | 3.86 | 7 | 2 | 0 | 12 | 12 | 0 | 0 | 86.1 | 85 | 39 | 37 | 12 | 51 | 9 | 3 |
| Jason Simontacchi | CTW | sp | 33 | 6.04 | 4 | 6 | 0 | 23 | 8 | 0 | 0 | 76.0 | 97 | 57 | 51 | 22 | 50 | 18 | 8 |
| Kevin Slowey | REN | sp | 23 | 5.88 | 3 | 2 | 1 | 48 | 0 | 0 | 0 | 72.0 | 88 | 50 | 47 | 17 | 57 | 12 | 4 |
| Joe Smith | CTW | mr | 23 | 7.75 | 2 | 3 | 0 | 28 | 0 | 0 | 0 | 36.0 | 38 | 31 | 31 | 22 | 36 | 4 | 2 |
| John Smoltz | BAR | sp | 40 | 3.59 | 16 | 4 | 0 | 33 | 33 | 0 | 0 | 200.1 | 193 | 83 | 80 | 36 | 192 | 30 | 8 |
| Ian Snell | RMO | sp | 25 | 4.13 | 3 | 2 | 3 | 32 | 0 | 0 | 0 | 52.1 | 44 | 25 | 24 | 21 | 44 | 7 | 5 |
| Kyle Snyder | NYD | mr | 29 | 5.06 | 1 | 1 | 1 | 10 | 3 | 0 | 0 | 16.0 | 13 | 12 | 9 | 13 | 14 | 3 | 2 |
| Andy Sonnanstine | NEP | sp | 24 | 4.70 | 5 | 7 | 1 | 34 | 18 | 1 | 0 | 128.1 | 144 | 71 | 67 | 25 | 118 | 21 | 4 |
| Joakim Soria |   | cl | 23 | 1.82 | 6 | 2 | 7 | 60 | 0 | 0 | 0 | 79.0 | 41 | 16 | 16 | 14 | 78 | 8 | 3 |
| Rafael Soriano | GAR | mr | 27 | 2.95 | 3 | 3 | 4 | 54 | 0 | 0 | 0 | 73.1 | 54 | 25 | 24 | 11 | 72 | 14 | 6 |
| Jorge Sosa | NYD | mr | 30 | 4.56 | 6 | 3 | 0 | 19 | 12 | 0 | 0 | 81.0 | 77 | 41 | 41 | 38 | 48 | 7 | 4 |
| Justin Speier | RMO | mr | 33 | 4.03 | 2 | 4 | 0 | 40 | 0 | 0 | 0 | 44.2 | 36 | 22 | 20 | 9 | 48 | 5 | 1 |
| Russ Springer | HAR | mr | 38 | 2.65 | 5 | 3 | 8 | 55 | 0 | 0 | 0 | 68.0 | 47 | 21 | 20 | 18 | 58 | 7 | 2 |
| Tim Stauffer | REN | sp | 25 | 15.58 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 8.2 | 15 | 16 | 15 | 7 | 5 | 5 | 1 |
| Mitch Stetter* | RYS | mr | 26 | 10.13 | 1 | 0 | 1 | 3 | 0 | 0 | 0 | 2.2 | 5 | 3 | 3 | 1 | 0 | 1 | 1 |
| Huston Street |   | cl | 23 | 2.50 | 1 | 3 | 7 | 30 | 0 | 0 | 0 | 39.2 | 31 | 12 | 11 | 13 | 46 | 3 | 2 |
| Eric Stults* | REN | mr | 27 | 3.48 | 0 | 0 | 0 | 15 | 0 | 0 | 0 | 20.2 | 21 | 8 | 8 | 8 | 14 | 2 | 1 |
| Jeff Suppan | BBG | sp | 32 | 5.11 | 7 | 14 | 0 | 30 | 29 | 0 | 0 | 169.0 | 209 | 109 | 96 | 54 | 91 | 16 | 18 |
| Brian Tallet* | BAR | mr | 29 | 2.70 | 2 | 3 | 1 | 53 | 0 | 0 | 0 | 70.0 | 52 | 27 | 21 | 16 | 65 | 8 | 3 |
| Taylor Tankersley* | HAR | mr | 24 | 10.13 | 0 | 1 | 2 | 11 | 0 | 0 | 0 | 10.2 | 18 | 12 | 12 | 7 | 11 | 5 | 0 |
| Julian Tavarez | CTW | sp | 34 | 4.70 | 2 | 5 | 0 | 51 | 1 | 0 | 0 | 82.1 | 97 | 45 | 43 | 23 | 47 | 13 | 12 |
| Robinson Tejeda | FDH | sp | 25 | 7.06 | 3 | 10 | 0 | 17 | 17 | 0 | 0 | 95.2 | 109 | 85 | 75 | 56 | 75 | 20 | 2 |
| Joe Thatcher* | BBG | mr | 25 | 1.42 | 2 | 2 | 1 | 12 | 0 | 0 | 0 | 19.0 | 9 | 3 | 3 | 5 | 11 | 1 | 1 |
| Brad Thompson | CTW | mr | 25 | 5.76 | 4 | 9 | 1 | 30 | 13 | 0 | 0 | 106.1 | 125 | 73 | 68 | 51 | 38 | 21 | 20 |
| Matt Thornton* | CIO | mr | 30 | 3.88 | 1 | 1 | 2 | 38 | 1 | 0 | 0 | 46.1 | 45 | 20 | 20 | 21 | 39 | 7 | 3 |
| Mike Timlin | CEN | mr | 41 | 2.81 | 3 | 1 | 3 | 20 | 0 | 0 | 0 | 25.2 | 22 | 9 | 8 | 1 | 8 | 6 | 2 |
| Brett Tomko | RYS | mr | 34 | 5.95 | 2 | 4 | 2 | 21 | 9 | 0 | 0 | 59.0 | 81 | 49 | 39 | 24 | 45 | 8 | 4 |
| Salomon Torres | PHI | mr | 35 | 0.00 | 1 | 0 | 2 | 7 | 0 | 0 | 0 | 7.2 | 9 | 1 | 0 | 0 | 6 | 0 | 0 |
| Josh Towers | CIO | sp | 30 | 1.08 | 0 | 1 | 0 | 4 | 0 | 0 | 0 | 8.1 | 12 | 2 | 1 | 2 | 9 | 0 | 1 |
| Steve Trachsel | FDH | sp | 36 | 5.34 | 1 | 5 | 0 | 10 | 10 | 0 | 0 | 59.0 | 72 | 37 | 35 | 25 | 20 | 8 | 8 |
| Derrick Turnbow | CIN | mr | 29 | 2.34 | 7 | 0 | 9 | 46 | 0 | 0 | 0 | 57.2 | 38 | 15 | 15 | 36 | 63 | 3 | 4 |
| Jose Valverde | SOI | cl | 27 | 4.06 | 9 | 4 | 5 | 54 | 1 | 0 | 0 | 64.1 | 56 | 34 | 29 | 30 | 78 | 9 | 3 |
| John Van Benschoten | CIO | sp | 27 | 10.51 | 0 | 3 | 1 | 28 | 2 | 0 | 0 | 37.2 | 62 | 55 | 44 | 36 | 23 | 7 | 3 |
| Rick VandenHurk | CTW | sp | 22 | 8.04 | 2 | 6 | 0 | 35 | 9 | 0 | 0 | 71.2 | 94 | 68 | 64 | 49 | 74 | 13 | 2 |
| Claudio Vargas | BRK | sp | 29 | 5.70 | 6 | 9 | 2 | 68 | 11 | 0 | 0 | 131.0 | 172 | 95 | 83 | 65 | 98 | 20 | 7 |
| Jason Vargas* | REN | sp | 24 | 8.03 | 0 | 3 | 0 | 3 | 3 | 0 | 0 | 12.1 | 20 | 12 | 11 | 4 | 9 | 2 | 0 |
| Javier Vazquez | SOI | sp | 30 | 4.04 | 16 | 6 | 0 | 32 | 32 | 2 | 0 | 213.2 | 197 | 100 | 96 | 44 | 217 | 37 | 13 |
| Jose Veras | RYS | mr | 26 | 7.56 | 0 | 2 | 1 | 6 | 0 | 0 | 0 | 8.1 | 9 | 7 | 7 | 5 | 3 | 0 | 1 |
| Justin Verlander | CTW | sp | 24 | 3.98 | 9 | 8 | 1 | 33 | 23 | 1 | 1 | 165.0 | 153 | 77 | 73 | 50 | 142 | 18 | 13 |
| Carlos Villanueva | CIN | mr | 23 | 4.07 | 6 | 6 | 2 | 31 | 17 | 1 | 1 | 117.1 | 94 | 55 | 53 | 53 | 100 | 21 | 8 |
| Oscar Villarreal | HAR | mr | 25 | 1.93 | 2 | 1 | 0 | 9 | 0 | 0 | 0 | 14.0 | 10 | 4 | 3 | 1 | 7 | 0 | 1 |
| Ron Villone* | CIN | mr | 37 | 6.55 | 2 | 3 | 4 | 18 | 0 | 0 | 0 | 22.0 | 25 | 18 | 16 | 9 | 15 | 8 | 1 |
| Luis Vizcaino | PHI | mr | 32 | 3.86 | 0 | 0 | 2 | 9 | 0 | 0 | 0 | 9.1 | 9 | 5 | 4 | 3 | 8 | 0 | 1 |
| Edinson Volquez | BAR | sp | 23 | 5.40 | 1 | 2 | 0 | 5 | 5 | 0 | 0 | 31.2 | 32 | 19 | 19 | 11 | 27 | 8 | 4 |
| Billy Wagner* | CIN | cl | 35 | 3.74 | 4 | 5 | 6 | 40 | 0 | 0 | 0 | 55.1 | 54 | 24 | 23 | 30 | 56 | 3 | 4 |
| Adam Wainwright | BRK | sp | 25 | 3.58 | 8 | 6 | 0 | 26 | 26 | 0 | 0 | 171.0 | 171 | 73 | 68 | 62 | 111 | 15 | 22 |
| Tim Wakefield | CIN | sp | 40 | 4.01 | 12 | 9 | 0 | 32 | 32 | 0 | 0 | 188.2 | 186 | 98 | 84 | 47 | 108 | 19 | 8 |
| Jamie Walker* | CBB | mr | 35 | 4.10 | 1 | 3 | 3 | 51 | 0 | 0 | 0 | 59.1 | 72 | 30 | 27 | 23 | 31 | 4 | 2 |
| Tyler Walker | REN | mr | 31 | 0.00 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 2.2 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
| Chien-Ming Wang | RMO | sp | 27 | 3.77 | 14 | 9 | 0 | 32 | 32 | 2 | 2 | 203.0 | 213 | 95 | 85 | 61 | 94 | 15 | 38 |
| Jarrod Washburn* | NEP | sp | 32 | 4.10 | 12 | 12 | 0 | 31 | 31 | 3 | 1 | 204.0 | 225 | 103 | 93 | 61 | 117 | 23 | 11 |
| David Weathers | CEN | cl | 37 | 2.84 | 4 | 5 | 9 | 51 | 0 | 0 | 0 | 69.2 | 58 | 25 | 22 | 25 | 33 | 1 | 4 |
| Jeff Weaver | NEP | sp | 30 | 3.30 | 0 | 2 | 0 | 7 | 7 | 0 | 0 | 46.1 | 46 | 22 | 17 | 7 | 25 | 5 | 3 |
| Jered Weaver | BBG | sp | 24 | 5.76 | 6 | 12 | 0 | 25 | 25 | 0 | 0 | 147.0 | 188 | 95 | 94 | 36 | 115 | 19 | 11 |
| Brandon Webb | BAR | sp | 28 | 2.49 | 19 | 6 | 0 | 32 | 32 | 4 | 2 | 216.2 | 170 | 77 | 60 | 51 | 178 | 10 | 18 |
| Todd Wellemeyer | TEW | mr | 28 | 4.27 | 5 | 3 | 6 | 54 | 0 | 0 | 0 | 71.2 | 68 | 39 | 34 | 35 | 49 | 14 | 7 |
| David Wells* | CTW | sp | 44 | 7.61 | 2 | 13 | 0 | 21 | 19 | 0 | 0 | 94.2 | 158 | 92 | 80 | 45 | 49 | 19 | 7 |
| Kip Wells |   | sp | 30 | 6.28 | 1 | 3 | 1 | 12 | 0 | 0 | 0 | 14.1 | 20 | 10 | 10 | 4 | 9 | 2 | 0 |
| Jake Westbrook | ATM | sp | 29 | 3.56 | 9 | 3 | 0 | 20 | 19 | 1 | 0 | 131.1 | 129 | 53 | 52 | 40 | 84 | 17 | 15 |
| Dan Wheeler | NEP | mr | 29 | 3.25 | 5 | 4 | 0 | 58 | 0 | 0 | 0 | 74.2 | 76 | 28 | 27 | 18 | 84 | 10 | 5 |
| Sean White | BRK | mr | 26 | 6.60 | 1 | 1 | 1 | 24 | 0 | 0 | 0 | 30.0 | 28 | 24 | 22 | 21 | 15 | 5 | 7 |
| Woody Williams | TEW | sp | 40 | 4.50 | 2 | 3 | 0 | 8 | 8 | 0 | 0 | 54.0 | 52 | 30 | 27 | 16 | 32 | 8 | 3 |
| Dontrelle Willis* | REN | sp | 25 | 5.83 | 5 | 15 | 0 | 29 | 29 | 2 | 0 | 174.1 | 193 | 125 | 113 | 83 | 127 | 28 | 12 |
| Brian Wilson | ATM | cl | 25 | 2.37 | 0 | 0 | 2 | 13 | 0 | 0 | 0 | 19.0 | 13 | 5 | 5 | 10 | 11 | 1 | 1 |
| C.J. Wilson* | BBG | mr | 26 | 4.18 | 3 | 1 | 4 | 51 | 0 | 0 | 0 | 56.0 | 62 | 27 | 26 | 36 | 50 | 4 | 8 |
| Matt Wise | CIN | mr | 31 | 2.70 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 3.1 | 2 | 1 | 1 | 0 | 3 | 1 | 0 |
| Randy Wolf* | BRK | sp | 30 | 4.95 | 3 | 7 | 0 | 15 | 15 | 0 | 0 | 80.0 | 93 | 52 | 44 | 45 | 77 | 6 | 4 |
| Kerry Wood | RYS | mr | 30 | 3.66 | 1 | 0 | 0 | 6 | 5 | 0 | 0 | 19.2 | 15 | 8 | 8 | 14 | 19 | 0 | 1 |
| Jamey Wright | FDH | mr | 32 | 5.20 | 6 | 2 | 1 | 53 | 0 | 0 | 0 | 72.2 | 86 | 49 | 42 | 34 | 38 | 7 | 12 |
| Michael Wuertz | NEP | mr | 28 | 3.38 | 4 | 5 | 2 | 61 | 0 | 0 | 0 | 77.1 | 64 | 31 | 29 | 35 | 72 | 4 | 8 |
| Chris Young | REN | sp | 28 | 3.83 | 8 | 7 | 0 | 36 | 24 | 1 | 1 | 150.1 | 118 | 65 | 64 | 74 | 172 | 15 | 4 |
| Carlos Zambrano | CEN | sp | 26 | 3.48 | 15 | 5 | 0 | 32 | 32 | 2 | 1 | 201.2 | 181 | 84 | 78 | 84 | 158 | 16 | 19 |
| Barry Zito* | RYS | sp | 29 | 5.03 | 8 | 10 | 1 | 41 | 28 | 1 | 0 | 182.1 | 194 | 106 | 102 | 86 | 131 | 33 | 15 |
| Joel Zumaya | CBB | mr | 22 | 3.00 | 2 | 0 | 0 | 19 | 0 | 0 | 0 | 24.0 | 22 | 9 | 8 | 11 | 19 | 2 | 1 |
| Secondary |
| Name | Team | P | Age | SB | CS | IW | HBP | WP | BK | SH | SF | H/9 | BB/9 | R/9 | K/9 | HR/9 | K/BB | WHIP |
| David Aardsma | CIO | mr | 25 | 0 | 1 | 3 | 2 | 5 | 0 | 1 | 3 | 13.9 | 6.5 | 21.1 | 10.4 | 0.9 | 1.6 | 2.27 |
| Jeremy Accardo | GAR | cl | 25 | 9 | 0 | 0 | 7 | 0 | 1 | 0 | 1 | 6.3 | 2.4 | 9.5 | 7.8 | 0.5 | 3.3 | 0.96 |
| Manny Acosta | BAR | mr | 26 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.0 | 4.5 | 4.5 | 4.5 | 0.0 | 1.0 | 0.50 |
| Jeremy Affeldt* | RYS | mr | 28 | 3 | 0 | 1 | 4 | 7 | 0 | 3 | 6 | 6.4 | 4.3 | 11.4 | 6.6 | 0.8 | 1.5 | 1.20 |
| Jonathan Albaladejo | GAR | mr | 24 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.3 | 1.2 | 5.5 | 4.9 | 0.6 | 4.0 | 0.61 |
| Matt Albers | RYS | sp | 24 | 4 | 2 | 2 | 9 | 4 | 0 | 7 | 7 | 10.3 | 4.1 | 15.2 | 5.7 | 1.6 | 1.4 | 1.60 |
| Tony Armas | FDH | mr | 29 | 5 | 1 | 0 | 5 | 0 | 0 | 1 | 5 | 9.2 | 2.8 | 12.9 | 6.2 | 1.4 | 2.2 | 1.33 |
| Bronson Arroyo | PHI | sp | 30 | 10 | 5 | 2 | 11 | 7 | 0 | 4 | 6 | 10.9 | 2.7 | 14.1 | 7.4 | 1.1 | 2.7 | 1.51 |
| Scott Atchison | ATM | mr | 31 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 8.5 | 2.3 | 11.1 | 11.4 | 1.3 | 5.0 | 1.19 |
| Luis Ayala | RMO | mr | 29 | 2 | 0 | 1 | 0 | 2 | 0 | 2 | 2 | 10.0 | 3.3 | 13.4 | 6.2 | 1.0 | 1.8 | 1.49 |
| Brandon Backe | BAR | sp | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 6.8 | 6.8 | 6.8 | 0.0 | 1.0 | 0.75 |
| Mike Bacsik* | BRK | sp | 29 | 0 | 0 | 3 | 1 | 1 | 0 | 0 | 3 | 17.5 | 2.8 | 20.6 | 2.0 | 3.6 | 0.7 | 2.25 |
| Cha Seung Baek | HAR | sp | 27 | 3 | 0 | 0 | 4 | 0 | 0 | 1 | 6 | 9.5 | 1.5 | 11.5 | 5.4 | 1.0 | 3.6 | 1.23 |
| Danys Baez | CTW | mr | 29 | 0 | 0 | 2 | 5 | 0 | 0 | 1 | 3 | 10.5 | 3.8 | 15.4 | 3.6 | 2.3 | 0.9 | 1.59 |
| Homer Bailey | FDH | sp | 21 | 8 | 0 | 0 | 3 | 0 | 0 | 2 | 3 | 7.6 | 5.2 | 13.4 | 4.9 | 0.4 | 1.0 | 1.42 |
| Scott Baker | BRK | sp | 25 | 14 | 2 | 12 | 5 | 0 | 0 | 3 | 5 | 8.9 | 3.2 | 12.5 | 6.8 | 0.8 | 2.1 | 1.35 |
| John Bale* | CEN | mr | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.0 | 0.0 | 6.0 | 9.0 | 0.0 | 99.0 | 0.67 |
| Grant Balfour | BBG | mr | 29 | 2 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 8.8 | 3.8 | 13.2 | 11.9 | 0.0 | 3.2 | 1.40 |
| Brian Bannister | NEP | sp | 26 | 6 | 3 | 2 | 6 | 1 | 0 | 9 | 3 | 10.1 | 2.1 | 12.5 | 4.1 | 1.0 | 2.0 | 1.35 |
| Miguel Batista | PHI | sp | 36 | 5 | 6 | 5 | 4 | 6 | 1 | 5 | 2 | 9.4 | 3.7 | 13.5 | 5.6 | 0.8 | 1.5 | 1.46 |
| Yorman Bazardo | NYD | mr | 22 | 7 | 1 | 0 | 1 | 2 | 0 | 1 | 2 | 8.7 | 1.0 | 10.0 | 2.4 | 0.7 | 2.3 | 1.08 |
| Josh Beckett | SOI | sp | 27 | 14 | 5 | 0 | 8 | 3 | 0 | 3 | 5 | 8.4 | 1.1 | 9.9 | 8.9 | 1.1 | 7.8 | 1.06 |
| Erik Bedard* | BAR | sp | 28 | 10 | 3 | 0 | 7 | 4 | 0 | 3 | 2 | 7.0 | 2.3 | 9.6 | 10.7 | 1.0 | 4.7 | 1.03 |
| Joe Beimel* | SOI | mr | 30 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 2.6 | 11.6 | 5.1 | 1.3 | 2.0 | 1.29 |
| Matt Belisle | FDH | sp | 27 | 17 | 8 | 2 | 2 | 5 | 0 | 2 | 5 | 10.7 | 2.4 | 13.3 | 5.8 | 1.1 | 2.4 | 1.46 |
| Heath Bell | NYD | mr | 29 | 9 | 1 | 3 | 1 | 1 | 0 | 3 | 2 | 8.0 | 3.8 | 11.9 | 11.7 | 0.9 | 3.1 | 1.31 |
| Jeff Bennett | REN | sp | 27 | 2 | 0 | 1 | 0 | 3 | 0 | 0 | 0 | 15.5 | 7.4 | 22.9 | 13.9 | 4.9 | 1.9 | 2.55 |
| Joaquin Benoit | NEP | mr | 29 | 5 | 0 | 1 | 3 | 3 | 0 | 0 | 0 | 7.6 | 2.5 | 10.5 | 10.4 | 0.7 | 4.1 | 1.13 |
| Jason Bergmann | RYS | sp | 25 | 3 | 1 | 4 | 3 | 0 | 0 | 1 | 2 | 11.6 | 4.7 | 16.9 | 6.9 | 1.9 | 1.5 | 1.81 |
| Rafael Betancourt | BAR | mr | 32 | 4 | 0 | 5 | 1 | 0 | 0 | 2 | 1 | 5.3 | 0.9 | 6.3 | 8.6 | 0.5 | 9.9 | 0.69 |
| Chad Billingsley | RMO | mr | 22 | 5 | 8 | 4 | 2 | 9 | 0 | 9 | 3 | 8.9 | 4.1 | 13.2 | 9.1 | 1.4 | 2.2 | 1.45 |
| Nick Blackburn | REN | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 13.2 | 1.4 | 14.5 | 9.0 | 2.1 | 6.5 | 1.62 |
| Joe Blanton | HAR | sp | 26 | 10 | 6 | 1 | 9 | 3 | 2 | 9 | 9 | 9.4 | 1.2 | 10.9 | 5.5 | 0.6 | 4.7 | 1.17 |
| Jerry Blevins* | CTW | mr | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 4.5 | 18.0 | 0.0 | 6.8 | 0.0 | 2.00 |
| Jeremy Bonderman | HAR | sp | 24 | 9 | 4 | 1 | 4 | 7 | 1 | 4 | 4 | 9.8 | 1.9 | 12.1 | 8.7 | 0.7 | 4.5 | 1.30 |
| Boof Bonser | CBB | sp | 25 | 2 | 1 | 4 | 0 | 2 | 2 | 3 | 3 | 13.2 | 4.8 | 18.1 | 6.4 | 2.0 | 1.3 | 2.01 |
| Joe Borowski | PHI | cl | 36 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 9.6 | 2.7 | 12.8 | 7.3 | 1.8 | 2.7 | 1.37 |
| Blaine Boyer | CBB | mr | 25 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 16.5 | 1.5 | 18.0 | 6.0 | 0.0 | 4.0 | 2.00 |
| Dallas Braden* | RYS | sp | 23 | 5 | 1 | 11 | 3 | 8 | 3 | 3 | 1 | 14.5 | 4.7 | 19.6 | 8.4 | 1.6 | 1.8 | 2.13 |
| Chad Bradford | CEN | mr | 32 | 0 | 0 | 0 | 4 | 0 | 0 | 3 | 1 | 8.8 | 1.1 | 10.6 | 3.9 | 0.4 | 3.5 | 1.10 |
| Bill Bray* | FDH | mr | 24 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 7.2 | 3.3 | 10.5 | 11.2 | 0.7 | 3.4 | 1.17 |
| Chris Britton | BAR | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.6 | 0.0 | 2.6 | 2.6 | 2.6 | 99.0 | 0.29 |
| Lance Broadway | NYD | mr | 23 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.2 | 4.2 | 10.4 | 11.1 | 0.0 | 2.7 | 1.15 |
| Doug Brocail | TEW | mr | 40 | 1 | 0 | 1 | 2 | 0 | 0 | 2 | 2 | 9.0 | 3.7 | 13.1 | 5.1 | 1.4 | 1.4 | 1.41 |
| Andrew Brown | HAR | mr | 26 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 7.9 | 2.4 | 10.7 | 11.1 | 1.2 | 4.7 | 1.15 |
| Jonathan Broxton | NYD | mr | 23 | 7 | 3 | 1 | 3 | 4 | 0 | 0 | 2 | 6.9 | 2.6 | 9.8 | 12.5 | 0.7 | 4.8 | 1.05 |
| Brian Bruney | BRK | mr | 25 | 5 | 0 | 8 | 1 | 2 | 0 | 3 | 4 | 7.1 | 8.8 | 16.1 | 6.9 | 1.6 | 0.8 | 1.76 |
| Clay Buchholz | RYS | sp | 22 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 5.2 | 4.4 | 9.7 | 6.9 | 0.4 | 1.5 | 1.07 |
| Taylor Buchholz | TEW | mr | 25 | 3 | 0 | 4 | 2 | 1 | 1 | 2 | 3 | 9.1 | 2.0 | 11.3 | 5.8 | 1.0 | 2.8 | 1.23 |
| Mark Buehrle* | RMO | sp | 28 | 2 | 3 | 5 | 5 | 0 | 0 | 8 | 2 | 9.1 | 2.5 | 11.7 | 5.4 | 1.1 | 2.2 | 1.28 |
| Jason Bulger | NEP | mr | 28 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 12.8 | 2.8 | 17.1 | 8.5 | 0.0 | 3.0 | 1.74 |
| A.J. Burnett | CIN | sp | 30 | 17 | 3 | 0 | 12 | 7 | 0 | 8 | 1 | 7.3 | 3.3 | 11.2 | 9.9 | 1.6 | 3.0 | 1.17 |
| Brian Burres* | BRK | mr | 26 | 3 | 3 | 4 | 2 | 2 | 0 | 1 | 1 | 10.5 | 4.3 | 15.3 | 7.6 | 0.9 | 1.7 | 1.65 |
| Jared Burton | SOI | mr | 26 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 10.5 | 6.0 | 16.5 | 9.0 | 0.0 | 1.5 | 1.83 |
| Dave Bush | NEP | sp | 27 | 12 | 4 | 1 | 7 | 0 | 0 | 9 | 6 | 10.1 | 2.3 | 12.7 | 6.9 | 0.9 | 3.0 | 1.38 |
| Paul Byrd | NEP | sp | 36 | 3 | 2 | 0 | 0 | 0 | 0 | 3 | 2 | 10.5 | 1.0 | 11.6 | 3.7 | 1.5 | 3.6 | 1.29 |
| Tim Byrdak* | CIN | mr | 33 | 2 | 0 | 2 | 0 | 4 | 0 | 4 | 1 | 6.6 | 3.8 | 10.4 | 10.4 | 0.9 | 2.7 | 1.15 |
| Daniel Cabrera | BBG | sp | 26 | 15 | 3 | 5 | 5 | 5 | 2 | 9 | 5 | 9.0 | 4.9 | 14.2 | 6.9 | 1.2 | 1.4 | 1.54 |
| Matt Cain | CEN | sp | 22 | 11 | 4 | 0 | 7 | 8 | 0 | 5 | 5 | 8.1 | 3.9 | 12.4 | 7.7 | 1.0 | 2.0 | 1.34 |
| Kiko Calero | CIO | mr | 32 | 5 | 3 | 2 | 0 | 0 | 0 | 1 | 5 | 11.1 | 4.1 | 15.2 | 5.3 | 1.0 | 1.3 | 1.69 |
| Kevin Cameron | REN | mr | 27 | 7 | 2 | 1 | 0 | 2 | 0 | 1 | 1 | 10.2 | 4.5 | 14.6 | 7.7 | 0.2 | 1.7 | 1.62 |
| Shawn Camp | ATM | mr | 31 | 0 | 1 | 0 | 2 | 4 | 0 | 2 | 1 | 14.8 | 4.4 | 19.6 | 7.8 | 0.4 | 1.8 | 2.13 |
| Jorge Campillo | NEP | mr | 28 | 3 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 13.5 | 5.1 | 18.6 | 6.8 | 0.8 | 1.3 | 2.06 |
| Matt Capps | NYD | mr | 23 | 5 | 1 | 5 | 6 | 0 | 0 | 0 | 2 | 7.9 | 1.6 | 10.1 | 6.6 | 0.6 | 4.1 | 1.05 |
| Buddy Carlyle | REN | sp | 29 | 8 | 0 | 10 | 2 | 4 | 0 | 1 | 5 | 8.7 | 2.1 | 11.0 | 6.5 | 1.9 | 3.0 | 1.20 |
| Fausto Carmona | RMO | sp | 26 | 11 | 4 | 1 | 14 | 2 | 2 | 8 | 2 | 7.2 | 2.5 | 10.3 | 6.6 | 0.7 | 2.6 | 1.07 |
| Chris Carpenter | CIO | sp | 32 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 15.0 | 6.0 | 21.0 | 4.5 | 0.0 | 0.8 | 2.33 |
| Santiago Casilla | BBG | mr | 26 | 2 | 0 | 0 | 2 | 8 | 0 | 0 | 0 | 7.8 | 2.7 | 10.8 | 8.1 | 1.5 | 2.9 | 1.17 |
| Shawn Chacon | RMO | mr | 29 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0.0 | 0.0 | 27.0 | 0.0 | 99.0 | 0.00 |
| Joba Chamberlain | BAR | mr | 21 | 2 | 0 | 0 | 2 | 1 | 0 | 1 | 0 | 2.0 | 2.3 | 5.0 | 14.7 | 0.3 | 6.3 | 0.48 |
| Bruce Chen* | REN | mr | 30 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 11.8 | 6.8 | 18.6 | 7.6 | 1.7 | 1.1 | 2.06 |
| Matt Chico* | CTW | sp | 24 | 8 | 0 | 5 | 8 | 2 | 0 | 2 | 4 | 11.1 | 5.1 | 16.8 | 4.4 | 1.4 | 0.9 | 1.79 |
| Randy Choate* | RYS | mr | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 18.0 | 9.0 | 27.0 | 0.0 | 0.0 | 0.0 | 3.00 |
| Roger Clemens | HAR | sp | 44 | 8 | 3 | 0 | 6 | 7 | 0 | 2 | 6 | 8.8 | 2.7 | 12.0 | 6.3 | 0.6 | 2.4 | 1.28 |
| Tyler Clippard | BRK | sp | 22 | 2 | 2 | 2 | 1 | 3 | 0 | 2 | 1 | 10.4 | 6.3 | 17.0 | 6.3 | 2.8 | 1.0 | 1.85 |
| Todd Coffey | RYS | mr | 26 | 3 | 0 | 0 | 2 | 1 | 0 | 2 | 4 | 14.7 | 4.3 | 19.3 | 5.3 | 2.8 | 1.3 | 2.10 |
| Jesus Colome | CIN | mr | 29 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 12.3 | 4.6 | 17.0 | 3.9 | 2.3 | 0.8 | 1.89 |
| Bartolo Colon | REN | sp | 34 | 4 | 1 | 3 | 1 | 0 | 0 | 5 | 5 | 14.6 | 2.6 | 17.3 | 6.6 | 2.5 | 2.6 | 1.91 |
| Clay Condrey | ATM | mr | 31 | 1 | 2 | 2 | 3 | 4 | 0 | 0 | 1 | 13.2 | 2.1 | 15.9 | 4.6 | 0.6 | 2.2 | 1.70 |
| Jose Contreras | NEP | sp | 35 | 26 | 8 | 3 | 18 | 4 | 0 | 11 | 9 | 11.9 | 2.8 | 15.5 | 5.6 | 1.0 | 2.0 | 1.63 |
| Aaron Cook | CIN | sp | 28 | 9 | 1 | 0 | 6 | 0 | 0 | 4 | 4 | 11.2 | 2.1 | 13.7 | 2.9 | 1.2 | 1.4 | 1.47 |
| Chad Cordero | SOI | cl | 25 | 2 | 1 | 0 | 2 | 7 | 2 | 1 | 2 | 8.4 | 2.7 | 11.3 | 7.8 | 0.7 | 2.8 | 1.23 |
| Francisco Cordero | CIN | cl | 32 | 4 | 1 | 2 | 3 | 1 | 0 | 2 | 0 | 7.9 | 3.1 | 11.4 | 12.5 | 0.7 | 4.0 | 1.22 |
| Lance Cormier | REN | sp | 26 | 3 | 0 | 0 | 0 | 2 | 0 | 4 | 3 | 13.1 | 3.4 | 16.5 | 4.1 | 2.1 | 1.2 | 1.83 |
| Manny Corpas | RMO | mr | 24 | 0 | 3 | 3 | 1 | 0 | 0 | 1 | 0 | 7.9 | 1.7 | 9.7 | 7.3 | 0.8 | 4.4 | 1.06 |
| Kevin Correia | ATM | mr | 26 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 9.5 | 2.2 | 11.7 | 7.9 | 0.8 | 3.6 | 1.30 |
| Neal Cotts* | FDH | mr | 27 | 1 | 0 | 0 | 2 | 2 | 0 | 1 | 1 | 12.2 | 4.6 | 17.8 | 3.1 | 0.0 | 0.7 | 1.87 |
| Jesse Crain | TEW | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.7 | 1.8 | 6.5 | 5.3 | 1.8 | 3.0 | 0.72 |
| Juan Cruz | HAR | mr | 28 | 1 | 1 | 5 | 3 | 2 | 3 | 1 | 0 | 5.8 | 3.2 | 9.3 | 13.4 | 1.0 | 4.3 | 0.99 |
| John Danks* | BRK | sp | 22 | 9 | 3 | 11 | 4 | 3 | 0 | 5 | 6 | 12.3 | 3.4 | 16.0 | 7.5 | 1.9 | 2.2 | 1.75 |
| Kyle Davies | CIO | sp | 23 | 8 | 2 | 8 | 8 | 4 | 0 | 1 | 1 | 12.2 | 6.0 | 19.3 | 7.8 | 1.6 | 1.3 | 2.03 |
| Doug Davis* | RYS | sp | 31 | 8 | 5 | 2 | 5 | 9 | 4 | 3 | 6 | 10.1 | 4.5 | 14.8 | 6.8 | 1.2 | 1.5 | 1.62 |
| Jorge De La Rosa* | CIO | sp | 26 | 6 | 6 | 20 | 4 | 3 | 2 | 8 | 4 | 11.4 | 3.9 | 15.5 | 6.0 | 1.8 | 1.5 | 1.69 |
| Manny Delcarmen | HAR | mr | 25 | 4 | 2 | 0 | 3 | 2 | 0 | 1 | 0 | 6.7 | 3.2 | 10.4 | 8.7 | 1.0 | 2.8 | 1.09 |
| Ryan Dempster | BAR | cl | 30 | 4 | 0 | 1 | 1 | 3 | 2 | 0 | 2 | 9.0 | 4.4 | 13.6 | 8.0 | 1.0 | 1.8 | 1.49 |
| Ross Detwiler* | HAR | mr | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0.0 | 0.0 | 7.7 | 0.0 | 99.0 | 0.00 |
| Joey Devine | ATM | mr | 23 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 12.4 | 4.5 | 16.9 | 10.1 | 0.0 | 2.3 | 1.88 |
| Lenny DiNardo* | RYS | sp | 27 | 5 | 1 | 3 | 5 | 3 | 0 | 5 | 5 | 11.0 | 4.9 | 16.3 | 3.6 | 1.6 | 0.7 | 1.77 |
| Brendan Donnelly | GAR | mr | 35 | 1 | 0 | 0 | 1 | 3 | 0 | 1 | 1 | 7.4 | 0.5 | 8.5 | 7.9 | 0.0 | 15.0 | 0.88 |
| Octavio Dotel | FDH | cl | 33 | 3 | 0 | 2 | 1 | 2 | 0 | 1 | 1 | 7.7 | 4.0 | 11.9 | 12.7 | 1.3 | 3.2 | 1.29 |
| Scott Downs* | SOI | mr | 31 | 1 | 2 | 3 | 2 | 4 | 1 | 2 | 1 | 8.2 | 4.8 | 13.3 | 8.2 | 0.8 | 1.7 | 1.45 |
| Justin Duchscherer | BAR | mr | 29 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 8.2 | 3.5 | 11.7 | 7.6 | 1.2 | 2.2 | 1.30 |
| Zach Duke* | CTW | sp | 24 | 4 | 4 | 2 | 3 | 0 | 2 | 5 | 4 | 13.8 | 3.5 | 17.6 | 3.6 | 1.3 | 1.0 | 1.93 |
| Chad Durbin | RYS | sp | 29 | 8 | 4 | 1 | 11 | 0 | 0 | 2 | 7 | 9.4 | 3.5 | 13.7 | 4.9 | 1.1 | 1.4 | 1.43 |
| J.D. Durbin | BRK | sp | 25 | 6 | 0 | 5 | 1 | 1 | 0 | 3 | 4 | 11.4 | 5.8 | 17.4 | 5.2 | 1.0 | 0.9 | 1.91 |
| Adam Eaton | CIO | sp | 29 | 10 | 3 | 15 | 8 | 6 | 0 | 5 | 8 | 10.8 | 6.3 | 17.8 | 5.5 | 1.6 | 0.9 | 1.90 |
| Scott Elarton | CIO | sp | 31 | 4 | 2 | 4 | 1 | 2 | 0 | 1 | 4 | 13.9 | 6.1 | 20.2 | 2.9 | 1.5 | 0.5 | 2.22 |
| Alan Embree* | CBB | cl | 37 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 18.0 | 0.0 | 99.0 | 1.00 |
| Kelvim Escobar | GAR | sp | 31 | 21 | 7 | 2 | 3 | 7 | 0 | 5 | 5 | 8.5 | 3.1 | 11.8 | 6.8 | 1.1 | 2.2 | 1.29 |
| Scott Feldman | BBG | mr | 24 | 3 | 0 | 0 | 2 | 2 | 0 | 0 | 3 | 10.4 | 7.1 | 17.9 | 6.0 | 1.3 | 0.8 | 1.94 |
| Pedro Feliciano* | SOI | mr | 30 | 0 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 9.3 | 6.0 | 15.7 | 7.7 | 0.4 | 1.3 | 1.70 |
| Gavin Floyd | CIN | sp | 24 | 6 | 2 | 2 | 2 | 1 | 0 | 3 | 3 | 9.3 | 2.4 | 11.9 | 6.6 | 1.9 | 2.7 | 1.30 |
| Josh Fogg | BBG | sp | 30 | 15 | 7 | 2 | 13 | 2 | 0 | 2 | 5 | 10.5 | 3.2 | 15.0 | 4.7 | 0.9 | 1.5 | 1.53 |
| Casey Fossum* | CTW | mr | 29 | 1 | 1 | 3 | 9 | 7 | 0 | 2 | 5 | 11.5 | 3.0 | 15.4 | 7.0 | 2.1 | 2.3 | 1.61 |
| Jeff Francis* | GAR | sp | 26 | 21 | 7 | 6 | 2 | 1 | 2 | 5 | 3 | 10.8 | 3.0 | 14.0 | 6.8 | 0.8 | 2.2 | 1.54 |
| Frank Francisco | NEP | mr | 27 | 3 | 0 | 0 | 3 | 8 | 0 | 2 | 3 | 8.9 | 5.8 | 15.2 | 7.4 | 0.9 | 1.3 | 1.63 |
| Ryan Franklin | CBB | mr | 34 | 1 | 1 | 0 | 4 | 0 | 0 | 2 | 3 | 9.1 | 0.9 | 10.5 | 4.9 | 1.2 | 5.5 | 1.12 |
| Jason Frasor | RYS | mr | 29 | 2 | 1 | 3 | 3 | 0 | 1 | 2 | 1 | 9.9 | 4.0 | 14.5 | 10.5 | 1.0 | 2.6 | 1.55 |
| Brian Fuentes* | HAR | cl | 31 | 3 | 0 | 0 | 2 | 2 | 0 | 2 | 3 | 7.9 | 4.5 | 12.8 | 8.5 | 1.0 | 1.9 | 1.39 |
| Aaron Fultz* | PHI | mr | 33 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 6.5 | 3.5 | 10.0 | 5.5 | 0.5 | 1.6 | 1.11 |
| Kason Gabbard* | NYD | sp | 25 | 7 | 2 | 1 | 6 | 4 | 0 | 4 | 2 | 4.9 | 4.6 | 10.0 | 6.0 | 0.4 | 1.3 | 1.05 |
| Eric Gagne | CEN | cl | 31 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 2 | 9.1 | 2.8 | 11.9 | 8.1 | 0.4 | 2.9 | 1.32 |
| Armando Galarraga | NEP | mr | 25 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 6.0 | 9.0 | 15.0 | 8.0 | 3.0 | 0.9 | 1.67 |
| Yovani Gallardo | PHI | sp | 21 | 8 | 6 | 3 | 5 | 3 | 0 | 4 | 2 | 9.2 | 3.1 | 12.7 | 8.9 | 1.3 | 2.9 | 1.36 |
| Freddy Garcia | CTW | sp | 31 | 3 | 0 | 5 | 1 | 5 | 0 | 2 | 2 | 10.0 | 3.5 | 13.7 | 8.2 | 1.6 | 2.4 | 1.50 |
| Lee Gardner | PHI | mr | 32 | 1 | 2 | 6 | 1 | 1 | 0 | 1 | 3 | 8.3 | 2.8 | 11.2 | 5.6 | 0.5 | 2.0 | 1.23 |
| Jon Garland | BAR | sp | 27 | 5 | 5 | 1 | 4 | 2 | 0 | 5 | 5 | 8.6 | 1.9 | 10.7 | 5.6 | 0.8 | 2.9 | 1.17 |
| Matt Garza | TEW | sp | 23 | 1 | 2 | 5 | 5 | 3 | 0 | 0 | 1 | 11.2 | 5.8 | 17.7 | 8.0 | 1.2 | 1.4 | 1.89 |
| Chad Gaudin | ATM | sp | 24 | 3 | 2 | 5 | 1 | 1 | 0 | 3 | 1 | 9.1 | 3.0 | 12.2 | 6.4 | 1.0 | 2.2 | 1.34 |
| Geoff Geary | NEP | mr | 30 | 3 | 3 | 0 | 10 | 2 | 0 | 3 | 2 | 10.8 | 3.2 | 15.4 | 4.9 | 1.3 | 1.5 | 1.56 |
| Justin Germano | TEW | sp | 24 | 10 | 1 | 2 | 7 | 0 | 0 | 6 | 2 | 9.5 | 2.9 | 13.3 | 4.4 | 1.5 | 1.5 | 1.38 |
| Dan Giese | CBB | mr | 30 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 9.0 | 2.5 | 12.3 | 8.2 | 1.6 | 3.3 | 1.27 |
| Tom Glavine* | BBG | sp | 41 | 8 | 3 | 1 | 3 | 1 | 0 | 9 | 7 | 12.7 | 3.5 | 16.3 | 4.0 | 1.2 | 1.1 | 1.79 |
| Mike Gonzalez* | BAR | mr | 29 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 10.8 | 19.8 | 9.0 | 1.8 | 0.8 | 2.20 |
| Tom Gordon | REN | mr | 39 | 5 | 2 | 0 | 2 | 0 | 0 | 3 | 1 | 10.3 | 4.0 | 14.7 | 7.8 | 1.8 | 1.9 | 1.59 |
| Tom Gorzelanny* | GAR | sp | 24 | 7 | 4 | 7 | 6 | 3 | 0 | 3 | 4 | 9.7 | 3.3 | 13.5 | 5.3 | 1.0 | 1.6 | 1.45 |
| John Grabow* | RYS | mr | 28 | 2 | 2 | 0 | 1 | 5 | 0 | 0 | 0 | 12.0 | 2.4 | 14.6 | 5.8 | 1.3 | 2.5 | 1.60 |
| Sean Green | ATM | mr | 28 | 1 | 0 | 1 | 3 | 0 | 0 | 1 | 0 | 10.1 | 3.4 | 14.5 | 4.7 | 1.0 | 1.4 | 1.50 |
| Kevin Gregg | RYS | cl | 29 | 2 | 0 | 1 | 1 | 7 | 0 | 1 | 4 | 9.1 | 6.4 | 15.6 | 9.1 | 1.5 | 1.4 | 1.72 |
| Zack Greinke | ATM | mr | 23 | 5 | 3 | 2 | 5 | 1 | 2 | 2 | 2 | 10.9 | 2.4 | 13.7 | 7.7 | 1.7 | 3.2 | 1.48 |
| Jason Grilli | ATM | mr | 30 | 3 | 2 | 2 | 4 | 4 | 0 | 2 | 2 | 9.5 | 3.4 | 13.4 | 7.1 | 0.9 | 2.1 | 1.43 |
| Eddie Guardado* | CTW | mr | 36 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 14.3 | 1.6 | 15.9 | 4.8 | 3.2 | 3.0 | 1.76 |
| Matt Guerrier | BAR | mr | 28 | 7 | 1 | 3 | 1 | 4 | 0 | 2 | 2 | 7.2 | 1.5 | 8.8 | 6.1 | 1.5 | 4.0 | 0.96 |
| Jeremy Guthrie | BAR | sp | 28 | 9 | 6 | 0 | 2 | 2 | 1 | 6 | 3 | 8.4 | 2.0 | 10.5 | 5.8 | 0.8 | 2.9 | 1.16 |
| Angel Guzman | CIO | mr | 25 | 0 | 1 | 6 | 3 | 4 | 0 | 4 | 1 | 9.4 | 5.1 | 15.7 | 8.2 | 0.4 | 1.6 | 1.61 |
| Roy Halladay | PHI | sp | 30 | 16 | 3 | 1 | 5 | 3 | 0 | 6 | 6 | 10.6 | 2.0 | 12.8 | 6.6 | 1.1 | 3.3 | 1.40 |
| Cole Hamels* | FDH | sp | 23 | 11 | 4 | 2 | 3 | 5 | 0 | 5 | 2 | 8.3 | 1.9 | 10.4 | 8.4 | 1.0 | 4.4 | 1.13 |
| Jason Hammel | REN | sp | 24 | 13 | 0 | 2 | 6 | 5 | 0 | 0 | 1 | 12.5 | 3.7 | 16.9 | 7.7 | 2.3 | 2.1 | 1.80 |
| Justin Hampson* | BAR | mr | 27 | 4 | 2 | 1 | 4 | 1 | 0 | 1 | 0 | 10.4 | 3.9 | 15.0 | 6.1 | 0.2 | 1.6 | 1.58 |
| Joel Hanrahan | BBG | sp | 25 | 6 | 1 | 0 | 1 | 0 | 0 | 5 | 2 | 13.5 | 6.4 | 20.1 | 7.1 | 3.0 | 1.1 | 2.21 |
| J.A. Happ* | RYS | sp | 24 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 19.1 | 6.4 | 25.4 | 1.6 | 4.8 | 0.3 | 2.82 |
| Aaron Harang | CBB | sp | 29 | 8 | 1 | 3 | 4 | 6 | 0 | 10 | 9 | 8.6 | 2.0 | 10.8 | 9.7 | 0.9 | 4.7 | 1.18 |
| Rich Harden | BRK | sp | 25 | 1 | 3 | 1 | 0 | 1 | 0 | 0 | 2 | 9.7 | 5.5 | 15.2 | 8.4 | 1.7 | 1.5 | 1.69 |
| Dan Haren | CIO | sp | 26 | 16 | 2 | 7 | 6 | 6 | 0 | 5 | 5 | 9.1 | 1.6 | 11.0 | 8.4 | 0.8 | 5.3 | 1.19 |
| LaTroy Hawkins | RMO | mr | 34 | 1 | 0 | 3 | 1 | 5 | 0 | 1 | 4 | 10.2 | 2.5 | 12.8 | 4.6 | 1.3 | 1.9 | 1.41 |
| Aaron Heilman | GAR | mr | 28 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 17.7 | 3.9 | 21.6 | 6.9 | 1.5 | 1.8 | 2.40 |
| Mark Hendrickson* | NYD | mr | 33 | 3 | 2 | 0 | 1 | 0 | 0 | 3 | 0 | 7.9 | 2.6 | 10.8 | 5.3 | 0.8 | 2.0 | 1.17 |
| Brad Hennessey | CIN | cl | 27 | 0 | 0 | 0 | 1 | 0 | 0 | 3 | 1 | 6.8 | 4.5 | 12.0 | 4.5 | 1.5 | 1.0 | 1.25 |
| Clay Hensley | TEW | sp | 27 | 4 | 0 | 1 | 1 | 1 | 0 | 3 | 2 | 13.6 | 6.7 | 20.5 | 7.4 | 1.4 | 1.1 | 2.26 |
| Matt Herges | CBB | mr | 37 | 1 | 0 | 1 | 2 | 0 | 1 | 1 | 0 | 7.3 | 2.0 | 9.7 | 4.7 | 0.4 | 2.4 | 1.03 |
| Felix Hernandez | CBB | sp | 21 | 8 | 4 | 10 | 7 | 4 | 1 | 3 | 4 | 10.0 | 2.5 | 12.8 | 7.4 | 1.2 | 3.0 | 1.39 |
| Livan Hernandez | FDH | sp | 32 | 6 | 2 | 0 | 2 | 0 | 5 | 2 | 3 | 12.8 | 3.6 | 16.6 | 3.9 | 1.3 | 1.1 | 1.82 |
| Orlando Hernandez | NYD | sp | 37 | 9 | 4 | 4 | 5 | 1 | 0 | 2 | 2 | 6.5 | 4.2 | 11.0 | 8.8 | 1.3 | 2.1 | 1.19 |
| Rich Hill* | SOI | sp | 27 | 16 | 7 | 4 | 12 | 1 | 2 | 2 | 9 | 8.0 | 3.9 | 12.5 | 8.7 | 1.1 | 2.2 | 1.32 |
| Shawn Hill | RMO | sp | 26 | 0 | 3 | 3 | 5 | 1 | 0 | 1 | 2 | 9.5 | 3.3 | 13.4 | 5.4 | 1.0 | 1.7 | 1.42 |
| Jason Hirsh | HAR | sp | 25 | 2 | 0 | 0 | 2 | 2 | 2 | 3 | 3 | 8.6 | 3.2 | 12.2 | 6.3 | 1.7 | 1.9 | 1.31 |
| Luke Hochevar | HAR | mr | 23 | 0 | 0 | 0 | 4 | 0 | 1 | 0 | 0 | 10.8 | 2.0 | 15.5 | 0.0 | 0.0 | 0.0 | 1.42 |
| Trevor Hoffman | GAR | cl | 39 | 2 | 1 | 3 | 0 | 0 | 0 | 1 | 2 | 6.6 | 1.7 | 8.3 | 7.0 | 0.4 | 4.2 | 0.92 |
| J.P. Howell* | CIO | sp | 24 | 2 | 1 | 5 | 4 | 0 | 0 | 2 | 3 | 10.3 | 3.2 | 14.2 | 8.9 | 1.9 | 2.8 | 1.50 |
| Bob Howry | GAR | mr | 33 | 2 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 10.9 | 2.1 | 13.5 | 7.3 | 2.6 | 3.5 | 1.44 |
| Tim Hudson | SOI | sp | 31 | 13 | 4 | 1 | 13 | 1 | 2 | 6 | 7 | 9.0 | 2.4 | 12.0 | 5.0 | 0.5 | 2.1 | 1.27 |
| Phil Hughes | NYD | sp | 21 | 6 | 4 | 4 | 3 | 2 | 0 | 1 | 5 | 6.8 | 3.0 | 10.1 | 6.4 | 1.5 | 2.1 | 1.09 |
| Philip Humber | BBG | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 12.5 | 1.9 | 14.5 | 1.0 | 1.0 | 0.5 | 1.61 |
| Jason Isringhausen | CEN | cl | 34 | 1 | 3 | 0 | 2 | 6 | 0 | 3 | 2 | 5.4 | 3.5 | 9.2 | 7.3 | 1.1 | 2.1 | 0.99 |
| Edwin Jackson | REN | sp | 23 | 14 | 4 | 5 | 5 | 2 | 3 | 8 | 5 | 9.1 | 4.0 | 13.4 | 6.5 | 1.2 | 1.6 | 1.45 |
| Chuck James* | FDH | sp | 25 | 4 | 1 | 0 | 0 | 0 | 1 | 2 | 2 | 8.4 | 3.2 | 11.5 | 6.0 | 1.5 | 1.9 | 1.28 |
| Casey Janssen | TEW | mr | 25 | 3 | 1 | 0 | 2 | 7 | 0 | 2 | 2 | 8.7 | 2.4 | 11.4 | 4.9 | 0.6 | 2.0 | 1.24 |
| Bobby Jenks | TEW | cl | 26 | 2 | 0 | 1 | 1 | 4 | 0 | 0 | 0 | 7.3 | 0.6 | 8.1 | 7.5 | 0.1 | 11.8 | 0.88 |
| Jason Jennings | BRK | sp | 28 | 9 | 2 | 8 | 3 | 0 | 0 | 6 | 4 | 10.3 | 3.7 | 14.4 | 6.4 | 1.2 | 1.7 | 1.56 |
| Ubaldo Jimenez | CIO | sp | 23 | 3 | 0 | 7 | 6 | 2 | 0 | 1 | 0 | 9.8 | 5.5 | 16.3 | 8.1 | 0.9 | 1.5 | 1.71 |
| Jim Johnson | TEW | mr | 24 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 162.0 | 54.0 | 216.0 | 0.0 | 0.0 | 0.0 | 24.00 |
| Josh Johnson | BBG | sp | 23 | 3 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 14.8 | 3.2 | 18.0 | 8.4 | 1.3 | 2.6 | 2.00 |
| Randy Johnson* | GAR | sp | 43 | 7 | 2 | 1 | 8 | 0 | 0 | 2 | 2 | 8.9 | 1.4 | 11.6 | 10.8 | 2.4 | 7.6 | 1.15 |
| Todd Jones | CTW | cl | 39 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 8.3 | 2.8 | 11.1 | 3.0 | 0.4 | 1.1 | 1.23 |
| Jair Jurrjens | NEP | sp | 21 | 2 | 0 | 1 | 0 | 3 | 0 | 0 | 1 | 7.3 | 4.0 | 11.3 | 4.7 | 1.0 | 1.2 | 1.26 |
| Jeff Karstens | FDH | mr | 24 | 1 | 0 | 0 | 1 | 4 | 0 | 0 | 2 | 19.6 | 8.1 | 28.3 | 8.8 | 4.0 | 1.1 | 3.07 |
| Scott Kazmir* | HAR | sp | 23 | 10 | 6 | 0 | 9 | 9 | 0 | 8 | 5 | 8.4 | 4.1 | 12.9 | 10.5 | 0.9 | 2.6 | 1.38 |
| Kyle Kendrick | CIN | sp | 22 | 12 | 1 | 6 | 11 | 0 | 0 | 1 | 0 | 8.4 | 2.2 | 11.3 | 3.2 | 1.0 | 1.5 | 1.17 |
| Ian Kennedy | BBG | sp | 22 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 4.9 | 3.4 | 8.3 | 11.8 | 0.5 | 3.4 | 0.93 |
| Byung-Hyun Kim | CTW | sp | 28 | 2 | 1 | 3 | 8 | 2 | 0 | 1 | 3 | 10.0 | 3.8 | 14.7 | 7.7 | 1.6 | 2.0 | 1.54 |
| Hong-Chih Kuo* | NYD | sp | 25 | 1 | 2 | 1 | 0 | 1 | 0 | 1 | 0 | 8.4 | 2.7 | 11.1 | 8.2 | 0.7 | 3.1 | 1.23 |
| John Lackey | GAR | sp | 28 | 12 | 3 | 1 | 12 | 7 | 3 | 7 | 7 | 7.9 | 1.7 | 10.1 | 8.0 | 1.1 | 4.7 | 1.06 |
| Aaron Laffey* | NYD | sp | 22 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 8.6 | 1.2 | 10.0 | 4.2 | 0.3 | 3.4 | 1.10 |
| John Lannan* | RYS | sp | 22 | 3 | 1 | 1 | 2 | 0 | 0 | 2 | 1 | 12.5 | 4.8 | 18.0 | 2.4 | 1.4 | 0.5 | 1.92 |
| Brandon League | ATM | mr | 24 | 0 | 0 | 2 | 0 | 5 | 0 | 2 | 0 | 21.0 | 5.0 | 26.0 | 9.0 | 0.0 | 1.8 | 2.89 |
| Cliff Lee* | BRK | sp | 28 | 6 | 1 | 2 | 4 | 3 | 0 | 4 | 2 | 10.5 | 3.6 | 14.5 | 6.9 | 2.5 | 1.9 | 1.57 |
| Jon Lester* | CIO | sp | 23 | 3 | 2 | 5 | 0 | 1 | 0 | 1 | 3 | 10.0 | 4.4 | 14.4 | 8.7 | 2.0 | 2.0 | 1.60 |
| Colby Lewis | BBG | mr | 27 | 1 | 0 | 3 | 3 | 0 | 1 | 2 | 4 | 15.8 | 3.9 | 20.4 | 7.3 | 1.7 | 1.9 | 2.19 |
| Jensen Lewis | BAR | mr | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.8 | 1.9 | 7.7 | 11.6 | 0.0 | 6.0 | 0.86 |
| Brad Lidge | BRK | cl | 30 | 4 | 0 | 3 | 3 | 3 | 0 | 4 | 1 | 11.3 | 3.9 | 15.8 | 13.1 | 2.1 | 3.3 | 1.69 |
| Ted Lilly* | CIN | sp | 31 | 9 | 5 | 1 | 8 | 3 | 0 | 4 | 4 | 8.6 | 2.6 | 11.6 | 9.1 | 2.3 | 3.5 | 1.24 |
| Tim Lincecum | NYD | sp | 23 | 17 | 5 | 0 | 0 | 8 | 0 | 9 | 2 | 7.6 | 4.1 | 11.7 | 9.0 | 0.9 | 2.2 | 1.30 |
| Matt Lindstrom | PHI | mr | 27 | 5 | 2 | 1 | 4 | 4 | 0 | 0 | 3 | 6.0 | 3.2 | 9.7 | 6.7 | 0.4 | 2.1 | 1.02 |
| Scott Linebrink | ATM | mr | 30 | 3 | 3 | 0 | 0 | 6 | 0 | 1 | 2 | 13.2 | 4.0 | 17.1 | 5.5 | 1.9 | 1.4 | 1.90 |
| Jesse Litsch | REN | sp | 22 | 8 | 4 | 2 | 3 | 1 | 0 | 4 | 2 | 9.0 | 3.0 | 12.2 | 4.9 | 1.3 | 1.7 | 1.33 |
| Wes Littleton | BAR | mr | 24 | 2 | 1 | 1 | 5 | 0 | 0 | 0 | 2 | 7.6 | 2.0 | 10.7 | 4.7 | 1.1 | 2.3 | 1.07 |
| Bobby Livingston* | PHI | sp | 24 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 20.8 | 2.1 | 22.8 | 6.2 | 2.1 | 3.0 | 2.54 |
| Kameron Loe | FDH | sp | 25 | 12 | 2 | 2 | 5 | 1 | 0 | 0 | 3 | 9.1 | 2.9 | 12.3 | 5.4 | 0.8 | 1.9 | 1.33 |
| Kyle Lohse | FDH | sp | 28 | 17 | 3 | 0 | 7 | 2 | 0 | 9 | 8 | 9.8 | 3.1 | 13.3 | 5.6 | 0.7 | 1.8 | 1.44 |
| Braden Looper | CBB | sp | 32 | 11 | 5 | 6 | 6 | 0 | 2 | 3 | 8 | 9.3 | 2.9 | 12.6 | 4.4 | 1.1 | 1.5 | 1.36 |
| Javier Lopez* | RYS | mr | 29 | 4 | 0 | 2 | 3 | 1 | 0 | 2 | 1 | 5.0 | 4.0 | 9.7 | 5.0 | 0.5 | 1.3 | 0.99 |
| Rodrigo Lopez | CBB | sp | 31 | 6 | 4 | 4 | 0 | 0 | 0 | 3 | 6 | 10.8 | 2.4 | 13.2 | 4.9 | 1.4 | 2.1 | 1.46 |
| Derek Lowe | TEW | sp | 34 | 8 | 0 | 5 | 3 | 1 | 3 | 6 | 4 | 9.0 | 3.8 | 12.9 | 6.8 | 0.9 | 1.8 | 1.42 |
| Mark Lowe | HAR | mr | 24 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.8 | 2.3 | 9.0 | 9.0 | 0.0 | 4.0 | 1.00 |
| Brandon Lyon | FDH | mr | 27 | 7 | 3 | 1 | 1 | 4 | 1 | 2 | 3 | 10.0 | 2.8 | 12.9 | 4.5 | 0.4 | 1.6 | 1.42 |
| Greg Maddux | CBB | sp | 41 | 16 | 5 | 3 | 11 | 3 | 0 | 8 | 10 | 11.2 | 1.1 | 12.8 | 5.3 | 0.6 | 4.8 | 1.37 |
| Ryan Madson | BBG | mr | 26 | 3 | 1 | 1 | 2 | 2 | 1 | 3 | 1 | 10.2 | 2.5 | 13.1 | 6.0 | 0.5 | 2.4 | 1.42 |
| Ron Mahay* | NYD | mr | 36 | 1 | 2 | 2 | 1 | 0 | 1 | 1 | 2 | 6.4 | 7.1 | 13.6 | 6.4 | 0.7 | 0.9 | 1.50 |
| John Maine | TEW | sp | 26 | 13 | 8 | 3 | 2 | 2 | 0 | 10 | 9 | 8.8 | 3.4 | 12.3 | 8.4 | 1.8 | 2.4 | 1.36 |
| Shaun Marcum | PHI | sp | 25 | 6 | 8 | 3 | 3 | 1 | 0 | 8 | 5 | 8.9 | 3.0 | 12.1 | 6.9 | 1.7 | 2.3 | 1.33 |
| Carlos Marmol | SOI | mr | 24 | 5 | 0 | 2 | 1 | 3 | 3 | 0 | 2 | 5.7 | 4.4 | 10.2 | 12.5 | 0.5 | 2.9 | 1.12 |
| Mike Maroth* | CIO | sp | 29 | 1 | 2 | 11 | 6 | 1 | 0 | 10 | 6 | 15.2 | 4.9 | 20.6 | 4.4 | 2.6 | 0.9 | 2.23 |
| Jason Marquis | CIO | sp | 28 | 19 | 7 | 12 | 12 | 1 | 0 | 6 | 8 | 9.1 | 4.9 | 14.7 | 5.0 | 0.9 | 1.0 | 1.56 |
| Sean Marshall* | BBG | sp | 24 | 6 | 0 | 2 | 3 | 3 | 0 | 1 | 3 | 10.3 | 3.6 | 14.2 | 6.0 | 0.6 | 1.7 | 1.54 |
| Damaso Marte* | ATM | mr | 32 | 1 | 1 | 4 | 3 | 0 | 1 | 3 | 1 | 9.5 | 4.1 | 14.5 | 10.4 | 0.8 | 2.5 | 1.52 |
| Pedro Martinez | CEN | sp | 35 | 2 | 2 | 0 | 3 | 3 | 0 | 1 | 1 | 10.6 | 1.9 | 13.2 | 7.1 | 1.1 | 3.9 | 1.38 |
| Nick Masset | CIO | mr | 25 | 5 | 2 | 5 | 2 | 5 | 0 | 3 | 0 | 10.5 | 6.0 | 16.9 | 4.9 | 0.8 | 0.8 | 1.83 |
| Daisuke Matsuzaka | CEN | sp | 26 | 11 | 3 | 1 | 10 | 3 | 0 | 8 | 4 | 7.5 | 3.2 | 11.1 | 9.4 | 1.2 | 3.0 | 1.19 |
| Brandon McCarthy | BRK | sp | 23 | 15 | 1 | 10 | 5 | 7 | 0 | 6 | 7 | 10.8 | 4.1 | 15.3 | 6.0 | 1.5 | 1.5 | 1.65 |
| Dustin McGowan | NYD | sp | 25 | 18 | 8 | 5 | 4 | 4 | 0 | 8 | 6 | 6.6 | 2.2 | 9.0 | 7.6 | 0.7 | 3.5 | 0.97 |
| Gil Meche | RMO | sp | 28 | 3 | 1 | 0 | 1 | 0 | 0 | 2 | 2 | 8.7 | 3.9 | 12.8 | 7.6 | 1.2 | 2.0 | 1.40 |
| Luis Mendoza | GAR | sp | 23 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 8.1 | 1.4 | 9.5 | 5.2 | 0.5 | 3.7 | 1.05 |
| Cla Meredith | CBB | mr | 24 | 2 | 1 | 2 | 3 | 0 | 1 | 0 | 1 | 11.8 | 3.2 | 15.6 | 6.3 | 0.5 | 1.9 | 1.67 |
| Jose Mesa |   | mr | 41 | 2 | 0 | 1 | 3 | 1 | 1 | 1 | 3 | 9.8 | 3.4 | 13.8 | 4.1 | 1.0 | 1.2 | 1.47 |
| Dan Meyer* | BRK | sp | 25 | 1 | 2 | 1 | 0 | 6 | 0 | 0 | 3 | 11.0 | 2.7 | 13.7 | 5.0 | 0.9 | 1.8 | 1.53 |
| Andrew Miller* | BRK | sp | 22 | 4 | 1 | 7 | 6 | 5 | 5 | 1 | 1 | 11.8 | 6.5 | 19.1 | 8.0 | 1.7 | 1.2 | 2.03 |
| Justin Miller | CIN | mr | 29 | 1 | 3 | 5 | 0 | 0 | 3 | 0 | 2 | 7.7 | 2.8 | 10.5 | 10.2 | 1.3 | 3.6 | 1.17 |
| Trever Miller* | CIN | mr | 34 | 1 | 1 | 2 | 4 | 2 | 0 | 1 | 2 | 8.8 | 4.5 | 14.3 | 6.0 | 1.4 | 1.3 | 1.49 |
| Kevin Millwood | CTW | sp | 32 | 3 | 4 | 5 | 8 | 2 | 0 | 6 | 2 | 8.8 | 2.6 | 11.8 | 5.0 | 1.3 | 1.9 | 1.27 |
| Sergio Mitre | NYD | sp | 26 | 4 | 1 | 0 | 2 | 4 | 0 | 4 | 3 | 12.8 | 2.2 | 15.2 | 5.8 | 1.0 | 2.6 | 1.67 |
| Franklin Morales* | GAR | sp | 21 | 4 | 0 | 1 | 2 | 1 | 0 | 1 | 1 | 8.6 | 4.3 | 13.5 | 7.2 | 1.3 | 1.7 | 1.43 |
| Brandon Morrow | TEW | mr | 22 | 6 | 2 | 3 | 2 | 3 | 0 | 1 | 7 | 9.0 | 6.3 | 15.6 | 9.0 | 0.6 | 1.4 | 1.70 |
| Dustin Moseley | PHI | mr | 25 | 7 | 1 | 0 | 5 | 6 | 1 | 2 | 3 | 10.3 | 2.1 | 12.8 | 5.5 | 0.6 | 2.7 | 1.37 |
| Guillermo Mota | BRK | mr | 33 | 5 | 1 | 7 | 7 | 2 | 0 | 0 | 1 | 13.0 | 5.2 | 19.3 | 6.2 | 2.3 | 1.2 | 2.02 |
| Jamie Moyer* | REN | sp | 44 | 19 | 7 | 6 | 6 | 4 | 0 | 9 | 9 | 11.5 | 2.8 | 14.6 | 7.1 | 1.4 | 2.6 | 1.59 |
| Peter Moylan | RMO | mr | 28 | 10 | 4 | 2 | 13 | 2 | 0 | 2 | 3 | 10.9 | 2.2 | 14.6 | 6.6 | 1.4 | 3.1 | 1.45 |
| Edward Mujica | ATM | mr | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.5 | 0.8 | 12.3 | 5.7 | 2.5 | 7.0 | 1.36 |
| Mike Mussina | PHI | sp | 38 | 11 | 2 | 7 | 3 | 1 | 0 | 5 | 5 | 12.4 | 1.8 | 14.3 | 7.3 | 1.7 | 4.2 | 1.57 |
| Brett Myers | PHI | cl | 26 | 5 | 2 | 4 | 0 | 4 | 0 | 1 | 1 | 8.4 | 4.3 | 12.7 | 11.7 | 1.2 | 2.7 | 1.41 |
| Joe Nathan | CEN | cl | 32 | 1 | 1 | 0 | 4 | 2 | 0 | 1 | 2 | 5.7 | 1.9 | 8.1 | 9.4 | 0.9 | 4.9 | 0.85 |
| Pat Neshek | NYD | mr | 26 | 0 | 0 | 0 | 3 | 1 | 0 | 2 | 1 | 4.1 | 2.5 | 7.0 | 10.4 | 1.3 | 4.2 | 0.74 |
| Ricky Nolasco | ATM | sp | 24 | 5 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 18.2 | 5.4 | 23.6 | 6.4 | 1.5 | 1.2 | 2.62 |
| Leo Nunez | ATM | mr | 23 | 9 | 0 | 5 | 1 | 1 | 0 | 3 | 0 | 7.8 | 2.3 | 10.3 | 6.6 | 2.3 | 2.9 | 1.12 |
| Eric O'Flaherty* | RYS | mr | 22 | 5 | 1 | 7 | 5 | 4 | 1 | 2 | 2 | 12.0 | 4.2 | 17.3 | 6.4 | 0.4 | 1.5 | 1.80 |
| Ross Ohlendorf | RYS | mr | 24 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.8 | 15.4 | 21.2 | 9.6 | 0.0 | 0.6 | 2.36 |
| Will Ohman* | NEP | mr | 29 | 3 | 1 | 2 | 0 | 3 | 0 | 2 | 0 | 10.0 | 3.2 | 13.2 | 7.3 | 0.2 | 2.3 | 1.46 |
| Hideki Okajima* | CBB | mr | 31 | 0 | 3 | 2 | 2 | 0 | 0 | 1 | 0 | 5.4 | 1.7 | 7.3 | 8.7 | 0.6 | 5.2 | 0.78 |
| Darren Oliver* | BBG | mr | 36 | 5 | 1 | 0 | 1 | 1 | 1 | 3 | 2 | 8.3 | 2.8 | 11.2 | 8.5 | 1.4 | 3.0 | 1.23 |
| Scott Olsen* | CIO | sp | 23 | 4 | 2 | 3 | 1 | 0 | 0 | 1 | 2 | 12.8 | 4.6 | 17.5 | 6.2 | 1.6 | 1.4 | 1.93 |
| Ramon Ortiz | FDH | mr | 34 | 7 | 0 | 2 | 5 | 0 | 1 | 6 | 5 | 10.7 | 1.9 | 13.1 | 5.2 | 1.6 | 2.7 | 1.41 |
| Roy Oswalt | CEN | sp | 29 | 6 | 8 | 0 | 10 | 0 | 2 | 5 | 3 | 9.2 | 2.2 | 11.8 | 6.8 | 0.6 | 3.1 | 1.26 |
| Akinori Otsuka | CEN | mr | 35 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 6.1 | 3.1 | 9.2 | 5.3 | 0.3 | 1.8 | 1.02 |
| Micah Owings | SOI | sp | 24 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 10.7 | 3.0 | 13.7 | 6.4 | 1.7 | 2.1 | 1.52 |
| Vicente Padilla | CIN | sp | 29 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 5.0 | 5.0 | 10.0 | 2.0 | 0.0 | 0.4 | 1.11 |
| Jonathan Papelbon | HAR | cl | 26 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 2 | 5.0 | 1.3 | 6.6 | 12.7 | 1.1 | 10.1 | 0.70 |
| Manny Parra* | NYD | mr | 24 | 2 | 1 | 0 | 1 | 2 | 0 | 2 | 1 | 11.5 | 6.9 | 18.8 | 7.9 | 0.3 | 1.1 | 2.05 |
| Troy Patton* | TEW | sp | 21 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 11.3 | 3.5 | 15.7 | 5.2 | 1.7 | 1.5 | 1.65 |
| Carl Pavano | NEP | sp | 31 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 7.6 | 1.8 | 9.4 | 3.5 | 1.8 | 2.0 | 1.04 |
| Jake Peavy | SOI | sp | 26 | 17 | 2 | 3 | 5 | 3 | 0 | 9 | 8 | 7.9 | 2.9 | 11.0 | 9.5 | 0.7 | 3.2 | 1.20 |
| Mike Pelfrey | REN | sp | 23 | 13 | 3 | 1 | 9 | 4 | 0 | 5 | 4 | 10.6 | 5.1 | 16.8 | 4.8 | 1.1 | 0.9 | 1.75 |
| Ramon Antonio Pena | GAR | mr | 25 | 2 | 0 | 2 | 3 | 0 | 1 | 0 | 0 | 8.4 | 2.6 | 11.5 | 8.1 | 1.1 | 3.1 | 1.22 |
| Brad Penny | RMO | sp | 29 | 9 | 9 | 2 | 6 | 4 | 0 | 5 | 4 | 10.2 | 3.2 | 13.6 | 6.2 | 0.4 | 2.0 | 1.48 |
| Joel Peralta | BBG | mr | 31 | 6 | 1 | 1 | 1 | 5 | 0 | 6 | 6 | 8.8 | 1.5 | 10.4 | 6.6 | 1.3 | 4.3 | 1.15 |
| Troy Percival | BAR | mr | 37 | 0 | 0 | 1 | 2 | 0 | 0 | 2 | 3 | 6.5 | 1.8 | 8.7 | 8.9 | 1.1 | 5.0 | 0.92 |
| Odalis Perez* | CIO | sp | 30 | 2 | 1 | 10 | 0 | 1 | 0 | 2 | 0 | 10.8 | 3.2 | 14.0 | 4.8 | 1.0 | 1.5 | 1.55 |
| Oliver Perez* | RMO | sp | 25 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 21.6 | 10.8 | 37.8 | 10.8 | 5.4 | 1.0 | 3.60 |
| Rafael Perez* | SOI | mr | 25 | 4 | 2 | 1 | 2 | 4 | 0 | 1 | 0 | 7.0 | 2.9 | 10.3 | 10.4 | 1.2 | 3.5 | 1.11 |
| Glen Perkins* | ATM | mr | 24 | 0 | 0 | 1 | 0 | 3 | 0 | 1 | 1 | 7.7 | 3.9 | 11.6 | 6.7 | 0.0 | 1.7 | 1.29 |
| Yusmeiro Petit | RYS | sp | 22 | 0 | 1 | 2 | 0 | 0 | 1 | 2 | 2 | 9.6 | 3.8 | 13.4 | 6.8 | 1.6 | 1.8 | 1.49 |
| Andy Pettitte* | HAR | sp | 35 | 5 | 3 | 0 | 2 | 4 | 0 | 8 | 7 | 12.2 | 2.7 | 15.0 | 5.5 | 0.9 | 2.1 | 1.65 |
| Joel Pineiro | BRK | mr | 28 | 11 | 1 | 8 | 4 | 2 | 0 | 2 | 1 | 9.9 | 3.8 | 14.2 | 6.3 | 1.3 | 1.7 | 1.52 |
| Scott Proctor | BBG | mr | 30 | 2 | 2 | 0 | 2 | 8 | 2 | 1 | 1 | 10.0 | 5.0 | 15.4 | 6.4 | 1.4 | 1.3 | 1.66 |
| J.J. Putz | HAR | cl | 30 | 3 | 2 | 0 | 2 | 3 | 0 | 3 | 0 | 4.3 | 1.9 | 6.5 | 10.7 | 0.8 | 5.6 | 0.69 |
| Chad Qualls | PHI | mr | 28 | 8 | 1 | 2 | 8 | 2 | 0 | 1 | 4 | 8.8 | 4.1 | 13.9 | 7.6 | 0.8 | 1.8 | 1.43 |
| Edwar Ramirez | TEW | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.9 | 3.9 | 7.7 | 7.7 | 3.9 | 2.0 | 0.86 |
| Horacio Ramirez* | CIO | sp | 27 | 5 | 4 | 14 | 4 | 0 | 0 | 5 | 4 | 10.8 | 5.1 | 16.2 | 3.7 | 1.3 | 0.7 | 1.76 |
| Ramon Ramirez | PHI | mr | 25 | 6 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 11.2 | 4.1 | 15.3 | 8.2 | 1.0 | 2.0 | 1.70 |
| Jon Rauch | CIN | mr | 28 | 5 | 0 | 1 | 1 | 0 | 0 | 2 | 2 | 7.1 | 2.0 | 9.2 | 5.8 | 0.7 | 2.9 | 1.01 |
| Chris Ray | NYD | cl | 25 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 3 | 4.8 | 3.5 | 8.7 | 6.5 | 0.9 | 1.9 | 0.92 |
| Tim Redding | CEN | sp | 29 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6.5 | 2.2 | 9.7 | 4.3 | 0.0 | 2.0 | 0.96 |
| Al Reyes | CBB | cl | 37 | 2 | 0 | 4 | 3 | 0 | 0 | 4 | 3 | 6.7 | 2.6 | 9.7 | 11.5 | 1.9 | 4.4 | 1.04 |
| Anthony Reyes | FDH | sp | 25 | 3 | 0 | 2 | 2 | 0 | 0 | 3 | 1 | 7.6 | 3.7 | 11.8 | 7.0 | 1.1 | 1.9 | 1.26 |
| David Riske | CBB | mr | 30 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 8.1 | 2.3 | 10.7 | 9.3 | 1.2 | 4.0 | 1.16 |
| Mariano Rivera | CTW | cl | 37 | 3 | 0 | 2 | 5 | 0 | 0 | 0 | 0 | 6.8 | 1.8 | 9.3 | 8.2 | 0.7 | 4.6 | 0.96 |
| Saul Rivera | PHI | mr | 29 | 5 | 0 | 2 | 2 | 8 | 0 | 3 | 4 | 11.4 | 7.3 | 19.0 | 5.8 | 0.6 | 0.8 | 2.08 |
| Nate Robertson* |   | sp | 29 | 11 | 2 | 2 | 4 | 1 | 1 | 4 | 4 | 11.0 | 2.8 | 14.2 | 5.5 | 1.2 | 2.0 | 1.53 |
| Fernando Rodney | BBG | mr | 30 | 8 | 0 | 2 | 1 | 6 | 0 | 2 | 1 | 9.3 | 4.2 | 13.7 | 9.6 | 0.9 | 2.3 | 1.50 |
| Francisco Rodriguez |   | cl | 25 | 8 | 1 | 0 | 1 | 10 | 1 | 2 | 1 | 6.2 | 3.9 | 10.3 | 12.9 | 0.5 | 3.3 | 1.13 |
| Wandy Rodriguez* | ATM | sp | 28 | 8 | 1 | 7 | 3 | 3 | 0 | 9 | 4 | 10.5 | 3.6 | 14.2 | 7.9 | 1.4 | 2.2 | 1.56 |
| Kenny Rogers* | CBB | sp | 42 | 2 | 0 | 2 | 1 | 1 | 0 | 3 | 0 | 9.4 | 2.9 | 12.5 | 6.1 | 1.2 | 2.1 | 1.37 |
| J.C. Romero* | PHI | mr | 31 | 1 | 0 | 3 | 2 | 4 | 0 | 2 | 3 | 6.4 | 5.2 | 11.9 | 5.1 | 0.8 | 1.0 | 1.29 |
| Ryan Rowland-Smith* | NEP | mr | 24 | 2 | 1 | 2 | 0 | 0 | 0 | 1 | 1 | 10.6 | 3.5 | 14.1 | 10.3 | 1.2 | 2.9 | 1.57 |
| B.J. Ryan* | CTW | cl | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 21.2 | 5.8 | 27.0 | 1.9 | 3.9 | 0.3 | 3.00 |
| Kirk Saarloos | REN | mr | 28 | 4 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 13.9 | 4.5 | 18.4 | 6.4 | 2.6 | 1.4 | 2.04 |
| C.C. Sabathia* | ATM | sp | 26 | 6 | 3 | 4 | 8 | 0 | 0 | 6 | 6 | 9.4 | 1.5 | 11.2 | 7.8 | 1.5 | 5.3 | 1.21 |
| Takashi Saito | GAR | cl | 37 | 2 | 2 | 4 | 2 | 0 | 0 | 2 | 1 | 6.3 | 3.3 | 9.8 | 10.0 | 1.8 | 3.0 | 1.06 |
| Chris Sampson | TEW | sp | 29 | 9 | 4 | 1 | 4 | 2 | 0 | 3 | 2 | 10.8 | 3.5 | 14.7 | 3.6 | 0.9 | 1.0 | 1.59 |
| Brian Sanches | BRK | mr | 28 | 0 | 0 | 1 | 0 | 3 | 0 | 4 | 1 | 8.2 | 6.6 | 14.8 | 6.1 | 4.1 | 0.9 | 1.64 |
| Anibal Sanchez | CIN | sp | 23 | 4 | 0 | 0 | 2 | 3 | 0 | 1 | 2 | 12.4 | 7.5 | 20.6 | 2.8 | 1.1 | 0.4 | 2.21 |
| Jonathan Sanchez* | RYS | mr | 24 | 6 | 4 | 3 | 3 | 4 | 0 | 4 | 3 | 11.6 | 5.9 | 18.1 | 10.7 | 1.3 | 1.8 | 1.95 |
| Ervin Santana | ATM | sp | 24 | 11 | 2 | 2 | 8 | 6 | 0 | 2 | 5 | 11.2 | 3.8 | 15.6 | 8.3 | 1.8 | 2.2 | 1.67 |
| Johan Santana* | GAR | sp | 28 | 6 | 6 | 3 | 6 | 3 | 2 | 6 | 4 | 8.0 | 1.8 | 10.1 | 9.8 | 2.0 | 5.4 | 1.09 |
| Dennis Sarfate | GAR | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.1 | 3.4 | 13.5 | 6.8 | 0.0 | 2.0 | 1.50 |
| Joe Saunders* | RMO | sp | 26 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 8.5 | 1.2 | 9.7 | 4.8 | 0.8 | 4.0 | 1.07 |
| Curt Schilling | CEN | sp | 40 | 1 | 2 | 0 | 5 | 0 | 0 | 9 | 3 | 8.0 | 1.2 | 9.5 | 7.0 | 1.4 | 5.7 | 1.02 |
| Chris Schroder | TEW | mr | 28 | 2 | 0 | 1 | 4 | 0 | 0 | 3 | 1 | 7.7 | 3.0 | 11.5 | 7.6 | 0.4 | 2.5 | 1.20 |
| Bobby Seay* | RYS | mr | 29 | 3 | 0 | 3 | 2 | 1 | 0 | 2 | 2 | 11.3 | 2.6 | 14.4 | 7.1 | 1.0 | 2.7 | 1.54 |
| Ben Sheets | TEW | sp | 28 | 14 | 2 | 2 | 4 | 2 | 0 | 3 | 3 | 8.8 | 2.2 | 11.3 | 7.9 | 1.8 | 3.5 | 1.23 |
| George Sherrill* | SOI | mr | 30 | 2 | 0 | 0 | 1 | 2 | 1 | 0 | 2 | 6.2 | 3.6 | 10.0 | 9.3 | 0.2 | 2.6 | 1.09 |
| James Shields | ATM | sp | 25 | 10 | 4 | 1 | 8 | 4 | 0 | 2 | 3 | 8.5 | 2.0 | 10.9 | 8.5 | 1.4 | 4.3 | 1.17 |
| Scot Shields | HAR | mr | 31 | 4 | 1 | 0 | 5 | 1 | 0 | 4 | 1 | 7.1 | 2.5 | 10.2 | 7.4 | 0.9 | 2.9 | 1.07 |
| Brian Shouse* | BRK | mr | 38 | 2 | 1 | 6 | 2 | 0 | 1 | 3 | 1 | 11.0 | 4.2 | 15.6 | 5.6 | 0.0 | 1.4 | 1.68 |
| Carlos Silva | TEW | sp | 28 | 1 | 2 | 1 | 0 | 1 | 2 | 2 | 1 | 8.9 | 1.3 | 10.1 | 5.3 | 0.9 | 4.3 | 1.12 |
| Jason Simontacchi | CTW | sp | 33 | 1 | 0 | 3 | 4 | 0 | 0 | 2 | 0 | 11.5 | 2.6 | 14.6 | 5.9 | 2.1 | 2.3 | 1.57 |
| Kevin Slowey | REN | sp | 23 | 2 | 1 | 3 | 1 | 0 | 0 | 2 | 5 | 11.0 | 2.1 | 13.3 | 7.1 | 1.5 | 3.4 | 1.46 |
| Joe Smith | CTW | mr | 23 | 3 | 1 | 4 | 5 | 1 | 0 | 2 | 1 | 9.5 | 5.5 | 16.3 | 9.0 | 1.0 | 1.6 | 1.67 |
| John Smoltz | BAR | sp | 40 | 12 | 6 | 0 | 2 | 4 | 0 | 3 | 5 | 8.7 | 1.6 | 10.4 | 8.6 | 1.3 | 5.3 | 1.14 |
| Ian Snell | RMO | sp | 25 | 5 | 2 | 1 | 1 | 1 | 0 | 3 | 1 | 7.6 | 3.6 | 11.4 | 7.6 | 1.2 | 2.1 | 1.24 |
| Kyle Snyder | NYD | mr | 29 | 2 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 7.3 | 7.3 | 14.6 | 7.9 | 1.7 | 1.1 | 1.63 |
| Andy Sonnanstine | NEP | sp | 24 | 7 | 7 | 1 | 9 | 0 | 0 | 5 | 2 | 10.1 | 1.8 | 12.5 | 8.3 | 1.5 | 4.7 | 1.32 |
| Joakim Soria |   | cl | 23 | 0 | 1 | 0 | 3 | 1 | 0 | 0 | 3 | 4.7 | 1.6 | 6.6 | 8.9 | 0.9 | 5.6 | 0.70 |
| Rafael Soriano | GAR | mr | 27 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 6.6 | 1.3 | 8.0 | 8.8 | 1.7 | 6.5 | 0.89 |
| Jorge Sosa | NYD | mr | 30 | 4 | 3 | 5 | 4 | 0 | 0 | 2 | 1 | 8.6 | 4.2 | 13.2 | 5.3 | 0.8 | 1.3 | 1.42 |
| Justin Speier | RMO | mr | 33 | 2 | 0 | 1 | 5 | 0 | 0 | 3 | 2 | 7.3 | 1.8 | 10.1 | 9.7 | 1.0 | 5.3 | 1.01 |
| Russ Springer | HAR | mr | 38 | 3 | 0 | 2 | 3 | 0 | 0 | 2 | 3 | 6.2 | 2.4 | 9.0 | 7.7 | 0.9 | 3.2 | 0.96 |
| Tim Stauffer | REN | sp | 25 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 15.6 | 7.3 | 23.9 | 5.2 | 5.2 | 0.7 | 2.54 |
| Mitch Stetter* | RYS | mr | 26 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 16.9 | 3.4 | 30.4 | 0.0 | 3.4 | 0.0 | 2.25 |
| Huston Street |   | cl | 23 | 2 | 1 | 3 | 0 | 0 | 0 | 2 | 3 | 7.0 | 2.9 | 10.0 | 10.4 | 0.7 | 3.5 | 1.11 |
| Eric Stults* | REN | mr | 27 | 0 | 1 | 1 | 0 | 3 | 0 | 2 | 0 | 9.1 | 3.5 | 12.6 | 6.1 | 0.9 | 1.8 | 1.40 |
| Jeff Suppan | BBG | sp | 32 | 13 | 6 | 4 | 12 | 6 | 0 | 10 | 11 | 11.1 | 2.9 | 14.6 | 4.8 | 0.9 | 1.7 | 1.56 |
| Brian Tallet* | BAR | mr | 29 | 3 | 3 | 0 | 5 | 0 | 0 | 1 | 4 | 6.7 | 2.1 | 9.4 | 8.4 | 1.0 | 4.1 | 0.97 |
| Taylor Tankersley* | HAR | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 15.2 | 5.9 | 21.1 | 9.3 | 4.2 | 1.6 | 2.34 |
| Julian Tavarez | CTW | sp | 34 | 3 | 3 | 5 | 3 | 1 | 0 | 1 | 5 | 10.6 | 2.5 | 13.4 | 5.1 | 1.4 | 2.0 | 1.46 |
| Robinson Tejeda | FDH | sp | 25 | 19 | 3 | 5 | 5 | 7 | 0 | 8 | 6 | 10.3 | 5.3 | 16.0 | 7.1 | 1.9 | 1.3 | 1.72 |
| Joe Thatcher* | BBG | mr | 25 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 4.3 | 2.4 | 6.6 | 5.2 | 0.5 | 2.2 | 0.74 |
| Brad Thompson | CTW | mr | 25 | 4 | 0 | 14 | 9 | 5 | 0 | 4 | 2 | 10.6 | 4.3 | 15.7 | 3.2 | 1.8 | 0.7 | 1.66 |
| Matt Thornton* | CIO | mr | 30 | 1 | 1 | 5 | 1 | 6 | 0 | 4 | 1 | 8.7 | 4.1 | 13.0 | 7.6 | 1.4 | 1.9 | 1.42 |
| Mike Timlin | CEN | mr | 41 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.7 | 0.4 | 8.1 | 2.8 | 2.1 | 8.0 | 0.90 |
| Brett Tomko | RYS | mr | 34 | 5 | 0 | 2 | 1 | 3 | 0 | 3 | 2 | 12.4 | 3.7 | 16.2 | 6.9 | 1.2 | 1.9 | 1.78 |
| Salomon Torres | PHI | mr | 35 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 10.6 | 0.0 | 10.6 | 7.0 | 0.0 | 99.0 | 1.17 |
| Josh Towers | CIO | sp | 30 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 13.0 | 2.2 | 15.1 | 9.7 | 0.0 | 4.5 | 1.68 |
| Steve Trachsel | FDH | sp | 36 | 5 | 3 | 0 | 0 | 0 | 0 | 4 | 1 | 11.0 | 3.8 | 14.8 | 3.1 | 1.2 | 0.8 | 1.64 |
| Derrick Turnbow | CIN | mr | 29 | 5 | 4 | 0 | 1 | 4 | 0 | 2 | 1 | 5.9 | 5.6 | 11.7 | 9.8 | 0.5 | 1.8 | 1.28 |
| Jose Valverde | SOI | cl | 27 | 7 | 0 | 0 | 1 | 1 | 1 | 2 | 1 | 7.8 | 4.2 | 12.2 | 10.9 | 1.3 | 2.6 | 1.34 |
| John Van Benschoten | CIO | sp | 27 | 4 | 2 | 4 | 7 | 0 | 0 | 2 | 1 | 14.8 | 8.6 | 25.1 | 5.5 | 1.7 | 0.6 | 2.60 |
| Rick VandenHurk | CTW | sp | 22 | 3 | 1 | 6 | 3 | 5 | 3 | 2 | 2 | 11.8 | 6.2 | 18.3 | 9.3 | 1.6 | 1.5 | 2.00 |
| Claudio Vargas | BRK | sp | 29 | 9 | 3 | 12 | 4 | 4 | 0 | 8 | 5 | 11.8 | 4.5 | 16.6 | 6.7 | 1.4 | 1.5 | 1.81 |
| Jason Vargas* | REN | sp | 24 | 0 | 1 | 3 | 1 | 2 | 0 | 3 | 0 | 14.6 | 2.9 | 18.2 | 6.6 | 1.5 | 2.3 | 1.95 |
| Javier Vazquez | SOI | sp | 30 | 8 | 6 | 1 | 9 | 6 | 0 | 6 | 5 | 8.3 | 1.9 | 10.5 | 9.1 | 1.6 | 4.9 | 1.13 |
| Jose Veras | RYS | mr | 26 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 9.7 | 5.4 | 15.1 | 3.2 | 0.0 | 0.6 | 1.68 |
| Justin Verlander | CTW | sp | 24 | 3 | 3 | 1 | 13 | 14 | 0 | 2 | 5 | 8.3 | 2.7 | 11.8 | 7.7 | 1.0 | 2.8 | 1.23 |
| Carlos Villanueva | CIN | mr | 23 | 6 | 0 | 0 | 4 | 1 | 0 | 6 | 7 | 7.2 | 4.1 | 11.6 | 7.7 | 1.6 | 1.9 | 1.25 |
| Oscar Villarreal | HAR | mr | 25 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 6.4 | 0.6 | 7.1 | 4.5 | 0.0 | 7.0 | 0.79 |
| Ron Villone* | CIN | mr | 37 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 10.2 | 3.7 | 14.7 | 6.1 | 3.3 | 1.7 | 1.55 |
| Luis Vizcaino | PHI | mr | 32 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 8.7 | 2.9 | 11.6 | 7.7 | 0.0 | 2.7 | 1.29 |
| Edinson Volquez | BAR | sp | 23 | 3 | 0 | 0 | 3 | 0 | 0 | 0 | 3 | 9.1 | 3.1 | 13.1 | 7.7 | 2.3 | 2.5 | 1.36 |
| Billy Wagner* | CIN | cl | 35 | 3 | 5 | 6 | 3 | 4 | 0 | 1 | 2 | 8.8 | 4.9 | 14.2 | 9.1 | 0.5 | 1.9 | 1.52 |
| Adam Wainwright | BRK | sp | 25 | 11 | 4 | 4 | 4 | 4 | 0 | 5 | 8 | 9.0 | 3.3 | 12.5 | 5.8 | 0.8 | 1.8 | 1.36 |
| Tim Wakefield | CIN | sp | 40 | 20 | 8 | 2 | 4 | 8 | 0 | 3 | 6 | 8.9 | 2.2 | 11.3 | 5.2 | 0.9 | 2.3 | 1.23 |
| Jamie Walker* | CBB | mr | 35 | 2 | 1 | 9 | 0 | 4 | 0 | 2 | 1 | 10.9 | 3.5 | 14.4 | 4.7 | 0.6 | 1.3 | 1.60 |
| Tyler Walker | REN | mr | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.4 | 3.4 | 6.8 | 3.4 | 0.0 | 1.0 | 0.75 |
| Chien-Ming Wang | RMO | sp | 27 | 13 | 6 | 7 | 11 | 12 | 2 | 5 | 6 | 9.4 | 2.7 | 12.6 | 4.2 | 0.7 | 1.5 | 1.35 |
| Jarrod Washburn* | NEP | sp | 32 | 14 | 5 | 2 | 6 | 0 | 2 | 11 | 4 | 9.9 | 2.7 | 12.9 | 5.2 | 1.0 | 1.9 | 1.40 |
| David Weathers | CEN | cl | 37 | 0 | 2 | 0 | 3 | 1 | 0 | 1 | 5 | 7.5 | 3.2 | 11.1 | 4.3 | 0.1 | 1.3 | 1.19 |
| Jeff Weaver | NEP | sp | 30 | 0 | 0 | 0 | 2 | 0 | 1 | 1 | 1 | 8.9 | 1.4 | 10.7 | 4.9 | 1.0 | 3.6 | 1.14 |
| Jered Weaver | BBG | sp | 24 | 11 | 4 | 1 | 2 | 2 | 0 | 3 | 5 | 11.5 | 2.2 | 13.8 | 7.0 | 1.2 | 3.2 | 1.52 |
| Brandon Webb | BAR | sp | 28 | 23 | 2 | 3 | 9 | 0 | 0 | 1 | 5 | 7.1 | 2.1 | 9.6 | 7.4 | 0.4 | 3.5 | 1.02 |
| Todd Wellemeyer | TEW | mr | 28 | 5 | 0 | 7 | 5 | 4 | 0 | 3 | 0 | 8.5 | 4.4 | 13.6 | 6.2 | 1.8 | 1.4 | 1.44 |
| David Wells* | CTW | sp | 44 | 8 | 2 | 15 | 1 | 0 | 0 | 2 | 1 | 15.0 | 4.3 | 19.4 | 4.7 | 1.8 | 1.1 | 2.14 |
| Kip Wells |   | sp | 30 | 1 | 0 | 1 | 1 | 3 | 0 | 3 | 1 | 12.6 | 2.5 | 15.7 | 5.7 | 1.3 | 2.3 | 1.67 |
| Jake Westbrook | ATM | sp | 29 | 14 | 5 | 5 | 4 | 0 | 0 | 3 | 4 | 8.8 | 2.7 | 11.9 | 5.8 | 1.2 | 2.1 | 1.29 |
| Dan Wheeler | NEP | mr | 29 | 3 | 2 | 0 | 0 | 0 | 0 | 4 | 2 | 9.2 | 2.2 | 11.3 | 10.1 | 1.2 | 4.7 | 1.26 |
| Sean White | BRK | mr | 26 | 2 | 0 | 2 | 4 | 4 | 0 | 0 | 1 | 8.4 | 6.3 | 15.9 | 4.5 | 1.5 | 0.7 | 1.63 |
| Woody Williams | TEW | sp | 40 | 2 | 2 | 3 | 3 | 0 | 0 | 3 | 4 | 8.7 | 2.7 | 11.8 | 5.3 | 1.3 | 2.0 | 1.26 |
| Dontrelle Willis* | REN | sp | 25 | 6 | 5 | 6 | 16 | 2 | 0 | 6 | 4 | 10.0 | 4.3 | 15.1 | 6.6 | 1.4 | 1.5 | 1.58 |
| Brian Wilson | ATM | cl | 25 | 0 | 1 | 3 | 1 | 1 | 0 | 1 | 0 | 6.2 | 4.7 | 11.4 | 5.2 | 0.5 | 1.1 | 1.21 |
| C.J. Wilson* | BBG | mr | 26 | 3 | 5 | 5 | 3 | 2 | 0 | 1 | 3 | 10.0 | 5.8 | 16.2 | 8.0 | 0.6 | 1.4 | 1.75 |
| Matt Wise | CIN | mr | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.4 | 0.0 | 5.4 | 8.1 | 2.7 | 99.0 | 0.60 |
| Randy Wolf* | BRK | sp | 30 | 11 | 4 | 5 | 1 | 1 | 0 | 2 | 5 | 10.5 | 5.1 | 15.6 | 8.7 | 0.7 | 1.7 | 1.72 |
| Kerry Wood | RYS | mr | 30 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 6.9 | 6.4 | 13.3 | 8.7 | 0.0 | 1.4 | 1.47 |
| Jamey Wright | FDH | mr | 32 | 0 | 1 | 0 | 2 | 1 | 0 | 3 | 3 | 10.7 | 4.2 | 15.1 | 4.7 | 0.9 | 1.1 | 1.65 |
| Michael Wuertz | NEP | mr | 28 | 10 | 2 | 0 | 0 | 5 | 0 | 0 | 2 | 7.4 | 4.1 | 11.5 | 8.4 | 0.5 | 2.1 | 1.28 |
| Chris Young | REN | sp | 28 | 16 | 3 | 9 | 9 | 5 | 3 | 6 | 2 | 7.1 | 4.4 | 12.0 | 10.3 | 0.9 | 2.3 | 1.28 |
| Carlos Zambrano | CEN | sp | 26 | 4 | 5 | 2 | 14 | 0 | 0 | 9 | 11 | 8.1 | 3.7 | 12.5 | 7.1 | 0.7 | 1.9 | 1.31 |
| Barry Zito* | RYS | sp | 29 | 4 | 4 | 6 | 4 | 5 | 0 | 3 | 5 | 9.6 | 4.2 | 14.0 | 6.5 | 1.6 | 1.5 | 1.54 |
| Joel Zumaya | CBB | mr | 22 | 0 | 0 | 4 | 0 | 2 | 0 | 0 | 1 | 8.3 | 4.1 | 12.4 | 7.1 | 0.8 | 1.7 | 1.38 |
| Analytical |
| Name | Team | P | Age | OPS | BIP | IPAVG | TBW | TBW/BF | TBWH | TBWH/BF | RC | RC27 | RCERA | CERA |
| David Aardsma | CIO | mr | 25 | .968 | 96 | .458 | 89 | .563 | 91 | .576 | 32.1 | 9.6 | 8.57 | 8.98 |
| Jeremy Accardo | GAR | cl | 25 | .526 | 199 | .231 | 89 | .306 | 96 | .330 | 20.6 | 2.5 | 2.31 | 2.06 |
| Manny Acosta | BAR | mr | 26 | .154 | 9 | .000 | 2 | .154 | 2 | .154 | 0.0 | 0.1 | 0.08 | 0.29 |
| Jeremy Affeldt* | RYS | mr | 28 | .692 | 165 | .230 | 107 | .433 | 111 | .449 | 25.9 | 3.9 | 3.49 | 3.05 |
| Jonathan Albaladejo | GAR | mr | 24 | .397 | 43 | .140 | 14 | .259 | 14 | .259 | 1.9 | 1.1 | 1.07 | 0.87 |
| Matt Albers | RYS | sp | 24 | .886 | 346 | .292 | 264 | .541 | 273 | .559 | 84.0 | 7.2 | 6.48 | 6.01 |
| Tony Armas | FDH | mr | 29 | .757 | 162 | .272 | 102 | .451 | 107 | .473 | 30.5 | 5.3 | 4.85 | 4.54 |
| Bronson Arroyo | PHI | sp | 30 | .813 | 611 | .336 | 420 | .490 | 431 | .502 | 129.3 | 6.1 | 5.53 | 5.22 |
| Scott Atchison | ATM | mr | 31 | .720 | 66 | .333 | 51 | .451 | 52 | .460 | 13.6 | 4.6 | 3.98 | 3.68 |
| Luis Ayala | RMO | mr | 29 | .763 | 112 | .313 | 70 | .458 | 70 | .458 | 21.5 | 5.7 | 4.97 | 4.69 |
| Brandon Backe | BAR | sp | 29 | .200 | 3 | .000 | 1 | .200 | 1 | .200 | 0.1 | 0.4 | 0.32 | 0.57 |
| Mike Bacsik* | BRK | sp | 29 | 1.140 | 98 | .357 | 84 | .700 | 85 | .708 | 34.6 | 13.7 | 12.37 | 12.16 |
| Cha Seung Baek | HAR | sp | 27 | .774 | 273 | .289 | 167 | .477 | 171 | .489 | 47.5 | 5.2 | 4.63 | 3.72 |
| Danys Baez | CTW | mr | 29 | .920 | 146 | .267 | 111 | .563 | 116 | .589 | 34.2 | 7.1 | 6.49 | 6.83 |
| Homer Bailey | FDH | sp | 21 | .645 | 136 | .257 | 72 | .379 | 75 | .395 | 18.3 | 3.7 | 3.40 | 3.80 |
| Scott Baker | BRK | sp | 25 | .711 | 358 | .296 | 215 | .427 | 220 | .437 | 56.8 | 4.3 | 3.92 | 3.75 |
| John Bale* | CEN | mr | 33 | .364 | 8 | .250 | 2 | .182 | 2 | .182 | 0.4 | 1.1 | 0.98 | 0.91 |
| Grant Balfour | BBG | mr | 29 | .688 | 76 | .368 | 52 | .406 | 54 | .422 | 14.6 | 4.5 | 4.14 | 3.47 |
| Brian Bannister | NEP | sp | 26 | .769 | 565 | .287 | 325 | .464 | 331 | .473 | 90.2 | 4.9 | 4.55 | 4.22 |
| Miguel Batista | PHI | sp | 36 | .742 | 376 | .293 | 228 | .449 | 232 | .457 | 60.8 | 4.6 | 4.31 | 4.32 |
| Yorman Bazardo | NYD | mr | 22 | .732 | 90 | .256 | 46 | .447 | 47 | .456 | 12.4 | 4.4 | 3.87 | 2.86 |
| Josh Beckett | SOI | sp | 27 | .660 | 549 | .291 | 320 | .399 | 328 | .408 | 78.9 | 3.5 | 3.23 | 2.97 |
| Erik Bedard* | BAR | sp | 28 | .622 | 467 | .278 | 304 | .389 | 311 | .398 | 68.6 | 3.2 | 2.81 | 2.61 |
| Joe Beimel* | SOI | mr | 30 | .729 | 23 | .261 | 14 | .467 | 14 | .467 | 3.9 | 5.0 | 4.53 | 3.83 |
| Matt Belisle | FDH | sp | 27 | .801 | 504 | .327 | 324 | .486 | 326 | .489 | 91.1 | 5.3 | 4.77 | 4.92 |
| Heath Bell | NYD | mr | 29 | .693 | 186 | .333 | 142 | .430 | 143 | .433 | 36.5 | 4.2 | 3.78 | 3.61 |
| Jeff Bennett | REN | sp | 27 | 1.231 | 28 | .464 | 48 | .800 | 48 | .800 | 19.7 | 16.6 | 14.47 | 14.85 |
| Joaquin Benoit | NEP | mr | 29 | .624 | 192 | .297 | 118 | .383 | 121 | .393 | 28.8 | 3.5 | 3.12 | 2.77 |
| Jason Bergmann | RYS | sp | 25 | .931 | 156 | .333 | 133 | .576 | 136 | .589 | 44.2 | 8.3 | 7.46 | 7.27 |
| Rafael Betancourt | BAR | mr | 32 | .456 | 211 | .209 | 85 | .280 | 86 | .283 | 15.0 | 1.6 | 1.47 | 1.08 |
| Chad Billingsley | RMO | mr | 22 | .787 | 399 | .306 | 315 | .496 | 317 | .499 | 86.0 | 5.3 | 4.81 | 4.63 |
| Nick Blackburn | REN | mr | 25 | .867 | 43 | .372 | 32 | .525 | 32 | .525 | 10.2 | 6.7 | 6.34 | 6.51 |
| Joe Blanton | HAR | sp | 26 | .675 | 721 | .298 | 351 | .386 | 360 | .396 | 92.2 | 3.7 | 3.38 | 3.22 |
| Jerry Blevins* | CTW | mr | 23 | 1.289 | 15 | .200 | 18 | .900 | 18 | .900 | 6.6 | 14.9 | 13.38 | 13.08 |
| Jeremy Bonderman | HAR | sp | 24 | .712 | 271 | .332 | 161 | .416 | 165 | .426 | 44.5 | 4.3 | 4.03 | 3.74 |
| Boof Bonser | CBB | sp | 25 | 1.046 | 121 | .364 | 112 | .647 | 112 | .647 | 39.7 | 10.2 | 9.11 | 8.43 |
| Joe Borowski | PHI | cl | 36 | .784 | 58 | .293 | 41 | .482 | 42 | .494 | 12.0 | 5.6 | 4.95 | 5.04 |
| Blaine Boyer | CBB | mr | 25 | .814 | 25 | .440 | 13 | .433 | 13 | .433 | 5.1 | 7.7 | 6.90 | 7.15 |
| Dallas Braden* | RYS | sp | 23 | 1.036 | 229 | .410 | 216 | .637 | 219 | .646 | 79.9 | 10.8 | 9.85 | 8.82 |
| Chad Bradford | CEN | mr | 32 | .607 | 167 | .269 | 65 | .325 | 69 | .345 | 17.5 | 3.3 | 2.93 | 2.78 |
| Bill Bray* | FDH | mr | 24 | .713 | 31 | .323 | 25 | .463 | 25 | .463 | 6.0 | 4.1 | 3.55 | 2.75 |
| Chris Britton | BAR | mr | 24 | .435 | 19 | .000 | 8 | .348 | 8 | .348 | 0.7 | 0.9 | 0.80 | 0.60 |
| Lance Broadway | NYD | mr | 23 | .496 | 31 | .290 | 16 | .302 | 16 | .302 | 3.0 | 2.0 | 1.85 | 2.07 |
| Doug Brocail | TEW | mr | 40 | .786 | 147 | .265 | 98 | .488 | 100 | .498 | 26.8 | 5.2 | 4.71 | 4.64 |
| Andrew Brown | HAR | mr | 26 | .746 | 53 | .321 | 43 | .473 | 44 | .484 | 10.1 | 4.0 | 3.60 | 3.40 |
| Jonathan Broxton | NYD | mr | 23 | .592 | 194 | .304 | 128 | .367 | 131 | .375 | 28.6 | 2.9 | 2.68 | 2.41 |
| Brian Bruney | BRK | mr | 25 | .799 | 143 | .217 | 127 | .525 | 128 | .529 | 33.6 | 5.8 | 5.33 | 5.46 |
| Clay Buchholz | RYS | sp | 22 | .520 | 61 | .197 | 31 | .344 | 31 | .344 | 5.3 | 2.1 | 1.91 | 1.86 |
| Taylor Buchholz | TEW | mr | 25 | .717 | 316 | .288 | 182 | .436 | 184 | .441 | 45.7 | 4.1 | 3.65 | 3.57 |
| Mark Buehrle* | RMO | sp | 28 | .729 | 647 | .280 | 381 | .445 | 386 | .451 | 96.5 | 4.2 | 3.82 | 3.86 |
| Jason Bulger | NEP | mr | 28 | .685 | 23 | .391 | 11 | .344 | 12 | .375 | 3.7 | 5.0 | 4.69 | 5.69 |
| A.J. Burnett | CIN | sp | 30 | .711 | 435 | .255 | 331 | .449 | 343 | .465 | 82.4 | 4.2 | 3.78 | 3.69 |
| Brian Burres* | BRK | mr | 26 | .807 | 122 | .344 | 87 | .483 | 89 | .494 | 25.0 | 5.6 | 5.15 | 5.46 |
| Jared Burton | SOI | mr | 26 | .624 | 21 | .333 | 11 | .355 | 11 | .355 | 3.0 | 4.1 | 4.10 | 4.79 |
| Dave Bush | NEP | sp | 27 | .780 | 578 | .318 | 371 | .471 | 378 | .480 | 106.9 | 5.3 | 4.79 | 4.32 |
| Paul Byrd | NEP | sp | 36 | .753 | 220 | .277 | 120 | .458 | 120 | .458 | 33.6 | 4.8 | 4.49 | 4.19 |
| Tim Byrdak* | CIN | mr | 33 | .616 | 129 | .256 | 85 | .394 | 85 | .394 | 19.3 | 3.3 | 3.00 | 2.61 |
| Daniel Cabrera | BBG | sp | 26 | .790 | 417 | .293 | 304 | .486 | 309 | .494 | 84.2 | 5.3 | 4.81 | 5.03 |
| Matt Cain | CEN | sp | 22 | .718 | 543 | .276 | 366 | .450 | 373 | .459 | 96.6 | 4.6 | 4.16 | 3.84 |
| Kiko Calero | CIO | mr | 32 | .840 | 130 | .323 | 88 | .509 | 88 | .509 | 28.0 | 6.7 | 6.07 | 5.55 |
| Kevin Cameron | REN | mr | 27 | .710 | 137 | .358 | 82 | .414 | 82 | .414 | 23.0 | 4.7 | 4.21 | 4.61 |
| Shawn Camp | ATM | mr | 31 | .958 | 142 | .465 | 110 | .545 | 112 | .554 | 36.1 | 7.7 | 7.08 | 8.48 |
| Jorge Campillo | NEP | mr | 28 | 1.091 | 37 | .405 | 34 | .654 | 34 | .654 | 13.2 | 11.5 | 10.02 | 7.89 |
| Matt Capps | NYD | mr | 23 | .631 | 230 | .278 | 115 | .367 | 121 | .387 | 27.7 | 3.2 | 2.84 | 2.60 |
| Buddy Carlyle | REN | sp | 29 | .805 | 290 | .252 | 215 | .531 | 217 | .536 | 56.7 | 5.2 | 4.75 | 3.81 |
| Fausto Carmona | RMO | sp | 26 | .630 | 538 | .253 | 285 | .375 | 299 | .393 | 64.3 | 3.0 | 2.74 | 2.73 |
| Chris Carpenter | CIO | sp | 32 | .896 | 24 | .417 | 16 | .516 | 16 | .516 | 5.4 | 8.0 | 7.24 | 8.14 |
| Santiago Casilla | BBG | mr | 26 | .680 | 155 | .252 | 101 | .433 | 103 | .442 | 24.3 | 3.9 | 3.54 | 3.45 |
| Shawn Chacon | RMO | mr | 29 | .000 | 0 | .000 | 0 | .000 | 0 | .000 | 0.0 | 0.0 | 0.00 | 0.00 |
| Joba Chamberlain | BAR | mr | 21 | .274 | 42 | .119 | 17 | .177 | 19 | .198 | 2.0 | 0.7 | 0.61 | 0.55 |
| Bruce Chen* | REN | mr | 30 | .938 | 34 | .353 | 31 | .585 | 31 | .585 | 10.3 | 8.7 | 7.86 | 8.20 |
| Matt Chico* | CTW | sp | 24 | .846 | 420 | .305 | 291 | .510 | 299 | .524 | 93.1 | 7.0 | 6.35 | 6.67 |
| Randy Choate* | RYS | mr | 31 | 1.000 | 5 | .400 | 3 | .500 | 3 | .500 | 1.4 | 12.5 | 11.26 | 12.01 |
| Roger Clemens | HAR | sp | 44 | .690 | 326 | .291 | 180 | .406 | 186 | .420 | 47.5 | 4.0 | 3.70 | 3.56 |
| Tyler Clippard | BRK | sp | 22 | 1.003 | 90 | .267 | 91 | .650 | 92 | .657 | 27.5 | 8.2 | 7.77 | 7.85 |
| Todd Coffey | RYS | mr | 26 | 1.058 | 155 | .361 | 138 | .642 | 140 | .651 | 50.8 | 10.5 | 9.71 | 10.34 |
| Jesus Colome | CIN | mr | 29 | .962 | 42 | .310 | 33 | .589 | 33 | .589 | 10.6 | 7.9 | 7.34 | 8.10 |
| Bartolo Colon | REN | sp | 34 | 1.040 | 333 | .381 | 294 | .645 | 295 | .647 | 107.8 | 10.4 | 9.25 | 8.85 |
| Clay Condrey | ATM | mr | 31 | .833 | 163 | .368 | 95 | .473 | 98 | .488 | 30.5 | 6.2 | 5.75 | 6.08 |
| Jose Contreras | NEP | sp | 35 | .849 | 694 | .346 | 448 | .488 | 466 | .508 | 147.2 | 6.6 | 6.03 | 5.97 |
| Aaron Cook | CIN | sp | 28 | .811 | 497 | .304 | 286 | .480 | 292 | .490 | 85.8 | 5.7 | 5.12 | 5.25 |
| Chad Cordero | SOI | cl | 25 | .638 | 234 | .286 | 128 | .383 | 130 | .389 | 31.9 | 3.6 | 3.29 | 3.20 |
| Francisco Cordero | CIN | cl | 32 | .648 | 144 | .333 | 101 | .393 | 104 | .405 | 26.3 | 3.9 | 3.51 | 3.16 |
| Lance Cormier | REN | sp | 26 | 1.031 | 152 | .336 | 126 | .640 | 126 | .640 | 43.0 | 9.2 | 8.30 | 7.94 |
| Manny Corpas | RMO | mr | 24 | .623 | 231 | .277 | 121 | .378 | 122 | .381 | 25.4 | 2.8 | 2.54 | 2.57 |
| Kevin Correia | ATM | mr | 26 | .690 | 138 | .319 | 81 | .420 | 81 | .420 | 21.2 | 4.1 | 3.79 | 3.66 |
| Neal Cotts* | FDH | mr | 27 | .907 | 70 | .343 | 46 | .529 | 48 | .552 | 15.2 | 7.5 | 6.99 | 6.20 |
| Jesse Crain | TEW | mr | 25 | .523 | 42 | .119 | 20 | .351 | 20 | .351 | 3.3 | 1.9 | 1.74 | 1.52 |
| Juan Cruz | HAR | mr | 28 | .573 | 134 | .261 | 98 | .370 | 101 | .381 | 20.0 | 2.7 | 2.47 | 2.10 |
| John Danks* | BRK | sp | 22 | .960 | 388 | .361 | 334 | .594 | 338 | .601 | 112.8 | 8.5 | 7.59 | 7.03 |
| Kyle Davies | CIO | sp | 23 | .994 | 221 | .357 | 211 | .613 | 219 | .637 | 75.0 | 10.0 | 9.06 | 8.22 |
| Doug Davis* | RYS | sp | 31 | .820 | 505 | .321 | 372 | .504 | 377 | .511 | 105.2 | 5.7 | 5.19 | 5.61 |
| Jorge De La Rosa* | CIO | sp | 26 | .909 | 443 | .321 | 348 | .563 | 352 | .570 | 105.2 | 6.9 | 6.41 | 6.31 |
| Manny Delcarmen | HAR | mr | 25 | .640 | 117 | .248 | 74 | .400 | 77 | .416 | 17.4 | 3.4 | 3.08 | 2.87 |
| Ryan Dempster | BAR | cl | 30 | .747 | 154 | .305 | 109 | .466 | 110 | .470 | 29.0 | 4.9 | 4.43 | 4.57 |
| Ross Detwiler* | HAR | mr | 21 | .000 | 5 | .000 | 0 | .000 | 0 | .000 | 0.0 | 0.0 | 0.00 | 0.00 |
| Joey Devine | ATM | mr | 23 | .807 | 26 | .423 | 18 | .462 | 18 | .462 | 6.2 | 7.0 | 6.26 | 5.73 |
| Lenny DiNardo* | RYS | sp | 27 | .915 | 421 | .302 | 317 | .563 | 322 | .572 | 97.7 | 7.2 | 6.51 | 6.91 |
| Brendan Donnelly | GAR | mr | 35 | .536 | 51 | .275 | 20 | .294 | 21 | .309 | 5.0 | 2.6 | 2.36 | 1.57 |
| Octavio Dotel | FDH | cl | 33 | .685 | 77 | .312 | 63 | .432 | 64 | .438 | 16.0 | 4.2 | 3.81 | 3.72 |
| Scott Downs* | SOI | mr | 31 | .660 | 162 | .284 | 100 | .400 | 102 | .408 | 24.5 | 3.8 | 3.55 | 4.00 |
| Justin Duchscherer | BAR | mr | 29 | .778 | 43 | .279 | 33 | .516 | 33 | .516 | 8.1 | 4.8 | 4.28 | 3.72 |
| Zach Duke* | CTW | sp | 24 | .986 | 407 | .364 | 303 | .593 | 306 | .599 | 102.8 | 8.6 | 7.78 | 7.91 |
| Chad Durbin | RYS | sp | 29 | .767 | 368 | .280 | 226 | .455 | 237 | .477 | 66.2 | 5.3 | 4.79 | 4.82 |
| J.D. Durbin | BRK | sp | 25 | .861 | 168 | .321 | 120 | .519 | 121 | .524 | 39.0 | 7.3 | 6.77 | 6.40 |
| Adam Eaton | CIO | sp | 29 | .902 | 374 | .299 | 301 | .553 | 309 | .568 | 97.0 | 7.8 | 7.21 | 6.99 |
| Scott Elarton | CIO | sp | 31 | 1.001 | 150 | .340 | 118 | .608 | 119 | .613 | 42.6 | 10.1 | 9.33 | 8.87 |
| Alan Embree* | CBB | cl | 37 | .500 | 2 | .500 | 1 | .250 | 1 | .250 | 0.3 | 2.3 | 2.03 | 1.95 |
| Kelvim Escobar | GAR | sp | 31 | .736 | 579 | .280 | 380 | .463 | 383 | .467 | 95.2 | 4.3 | 3.95 | 3.76 |
| Scott Feldman | BBG | mr | 24 | .906 | 131 | .313 | 112 | .566 | 114 | .576 | 35.8 | 8.0 | 7.12 | 7.24 |
| Pedro Feliciano* | SOI | mr | 30 | .801 | 67 | .328 | 51 | .495 | 52 | .505 | 13.9 | 5.6 | 5.06 | 4.84 |
| Gavin Floyd | CIN | sp | 24 | .786 | 208 | .279 | 144 | .486 | 146 | .493 | 37.7 | 4.8 | 4.30 | 4.63 |
| Josh Fogg | BBG | sp | 30 | .836 | 315 | .311 | 204 | .488 | 217 | .519 | 65.9 | 6.4 | 5.82 | 5.41 |
| Casey Fossum* | CTW | mr | 29 | .924 | 261 | .333 | 213 | .556 | 222 | .580 | 67.7 | 7.3 | 6.53 | 6.99 |
| Jeff Francis* | GAR | sp | 26 | .783 | 647 | .349 | 414 | .467 | 416 | .470 | 121.1 | 5.4 | 4.86 | 4.94 |
| Frank Francisco | NEP | mr | 27 | .767 | 178 | .298 | 129 | .471 | 132 | .482 | 37.5 | 5.7 | 5.11 | 5.17 |
| Ryan Franklin | CBB | mr | 34 | .707 | 265 | .268 | 141 | .425 | 145 | .437 | 37.7 | 4.2 | 3.79 | 3.39 |
| Jason Frasor | RYS | mr | 29 | .810 | 146 | .349 | 118 | .496 | 121 | .508 | 35.0 | 6.0 | 5.48 | 4.98 |
| Brian Fuentes* | HAR | cl | 31 | .704 | 172 | .273 | 119 | .441 | 121 | .448 | 31.0 | 4.5 | 4.09 | 3.97 |
| Aaron Fultz* | PHI | mr | 33 | .608 | 52 | .231 | 27 | .380 | 27 | .380 | 6.0 | 3.1 | 2.72 | 2.30 |
| Kason Gabbard* | NYD | sp | 25 | .535 | 244 | .184 | 122 | .339 | 128 | .356 | 23.5 | 2.3 | 2.10 | 2.03 |
| Eric Gagne | CEN | cl | 31 | .665 | 77 | .325 | 43 | .394 | 43 | .394 | 11.3 | 4.0 | 3.56 | 3.31 |
| Armando Galarraga | NEP | mr | 25 | .812 | 22 | .136 | 24 | .571 | 24 | .571 | 6.1 | 5.9 | 5.51 | 6.25 |
| Yovani Gallardo | PHI | sp | 21 | .751 | 301 | .309 | 212 | .460 | 217 | .471 | 58.2 | 4.9 | 4.46 | 4.36 |
| Freddy Garcia | CTW | sp | 31 | .857 | 162 | .315 | 133 | .545 | 134 | .549 | 39.9 | 6.6 | 5.91 | 5.16 |
| Lee Gardner | PHI | mr | 32 | .628 | 212 | .274 | 104 | .371 | 105 | .375 | 25.6 | 3.5 | 3.09 | 2.97 |
| Jon Garland | BAR | sp | 27 | .678 | 547 | .276 | 291 | .409 | 295 | .415 | 73.5 | 3.8 | 3.43 | 3.14 |
| Matt Garza | TEW | sp | 23 | .869 | 189 | .365 | 155 | .522 | 160 | .539 | 48.1 | 7.1 | 6.28 | 7.07 |
| Chad Gaudin | ATM | sp | 24 | .725 | 158 | .291 | 96 | .438 | 97 | .443 | 25.1 | 4.4 | 3.94 | 3.90 |
| Geoff Geary | NEP | mr | 30 | .817 | 208 | .317 | 129 | .456 | 139 | .491 | 39.7 | 5.7 | 5.16 | 6.19 |
| Justin Germano | TEW | sp | 24 | .808 | 253 | .273 | 162 | .482 | 169 | .503 | 46.8 | 5.4 | 4.90 | 4.97 |
| Dan Giese | CBB | mr | 30 | .767 | 32 | .281 | 23 | .479 | 24 | .500 | 6.1 | 4.9 | 4.52 | 4.40 |
| Tom Glavine* | BBG | sp | 41 | .899 | 618 | .340 | 420 | .538 | 423 | .542 | 135.5 | 7.2 | 6.65 | 6.75 |
| Mike Gonzalez* | BAR | mr | 29 | 1.019 | 13 | .308 | 17 | .680 | 17 | .680 | 5.2 | 9.4 | 8.48 | 8.46 |
| Tom Gordon | REN | mr | 39 | .833 | 121 | .314 | 93 | .505 | 95 | .516 | 28.1 | 6.2 | 5.65 | 6.01 |
| Tom Gorzelanny* | GAR | sp | 24 | .784 | 397 | .295 | 255 | .478 | 261 | .489 | 72.4 | 5.4 | 4.83 | 4.63 |
| John Grabow* | RYS | mr | 28 | .776 | 148 | .338 | 87 | .451 | 88 | .456 | 27.6 | 5.9 | 5.31 | 5.78 |
| Sean Green | ATM | mr | 28 | .833 | 85 | .318 | 56 | .487 | 59 | .513 | 16.1 | 5.6 | 4.90 | 5.44 |
| Kevin Gregg | RYS | cl | 29 | .849 | 164 | .305 | 151 | .545 | 152 | .549 | 43.3 | 6.5 | 5.91 | 5.92 |
| Zack Greinke | ATM | mr | 23 | .899 | 344 | .340 | 283 | .566 | 288 | .576 | 82.8 | 6.5 | 5.83 | 5.69 |
| Jason Grilli | ATM | mr | 30 | .786 | 209 | .311 | 144 | .480 | 148 | .493 | 41.3 | 5.5 | 4.89 | 4.51 |
| Eddie Guardado* | CTW | mr | 36 | 1.115 | 42 | .333 | 40 | .741 | 40 | .741 | 14.5 | 11.5 | 10.33 | 8.56 |
| Matt Guerrier | BAR | mr | 28 | .645 | 270 | .219 | 152 | .414 | 153 | .417 | 32.9 | 3.1 | 2.82 | 2.57 |
| Jeremy Guthrie | BAR | sp | 28 | .666 | 537 | .276 | 284 | .403 | 286 | .406 | 68.3 | 3.5 | 3.18 | 3.04 |
| Angel Guzman | CIO | mr | 25 | .863 | 68 | .338 | 53 | .500 | 56 | .528 | 15.8 | 6.2 | 5.56 | 4.59 |
| Roy Halladay | PHI | sp | 30 | .780 | 705 | .332 | 443 | .467 | 448 | .473 | 123.0 | 4.9 | 4.51 | 4.61 |
| Cole Hamels* | FDH | sp | 23 | .671 | 416 | .291 | 250 | .411 | 253 | .415 | 61.6 | 3.7 | 3.32 | 3.08 |
| Jason Hammel | REN | sp | 24 | .997 | 263 | .354 | 248 | .629 | 254 | .645 | 86.2 | 9.4 | 8.52 | 8.02 |
| Justin Hampson* | BAR | mr | 27 | .758 | 162 | .340 | 97 | .439 | 101 | .457 | 28.0 | 5.1 | 4.66 | 4.76 |
| Joel Hanrahan | BBG | sp | 25 | 1.106 | 156 | .359 | 168 | .686 | 169 | .690 | 63.6 | 12.2 | 10.73 | 10.83 |
| J.A. Happ* | RYS | sp | 24 | 1.379 | 22 | .409 | 26 | .867 | 26 | .867 | 10.1 | 16.0 | 14.43 | 18.42 |
| Aaron Harang | CBB | sp | 29 | .695 | 644 | .315 | 418 | .426 | 422 | .430 | 107.2 | 4.1 | 3.65 | 3.16 |
| Rich Harden | BRK | sp | 25 | .841 | 58 | .328 | 50 | .526 | 50 | .526 | 13.6 | 5.7 | 5.16 | 6.18 |
| Dan Haren | CIO | sp | 26 | .701 | 531 | .313 | 319 | .424 | 325 | .432 | 84.8 | 4.2 | 3.82 | 3.23 |
| LaTroy Hawkins | RMO | mr | 34 | .792 | 179 | .302 | 110 | .476 | 111 | .481 | 29.4 | 4.8 | 4.36 | 4.78 |
| Aaron Heilman | GAR | mr | 28 | .997 | 48 | .438 | 38 | .594 | 38 | .594 | 15.3 | 11.5 | 10.66 | 10.52 |
| Mark Hendrickson* | NYD | mr | 33 | .637 | 136 | .257 | 68 | .378 | 69 | .383 | 15.8 | 3.2 | 2.88 | 3.10 |
| Brad Hennessey | CIN | cl | 27 | .795 | 34 | .206 | 23 | .469 | 24 | .490 | 6.0 | 4.6 | 4.03 | 4.06 |
| Clay Hensley | TEW | sp | 27 | 1.012 | 127 | .402 | 117 | .606 | 118 | .611 | 43.4 | 10.7 | 9.34 | 9.45 |
| Matt Herges | CBB | mr | 37 | .589 | 159 | .239 | 71 | .355 | 73 | .365 | 16.0 | 2.9 | 2.63 | 2.16 |
| Felix Hernandez | CBB | sp | 21 | .783 | 568 | .324 | 385 | .477 | 392 | .486 | 105.1 | 5.0 | 4.53 | 4.56 |
| Livan Hernandez | FDH | sp | 32 | .933 | 247 | .348 | 177 | .562 | 179 | .568 | 59.1 | 7.9 | 7.07 | 7.25 |
| Orlando Hernandez | NYD | sp | 37 | .658 | 395 | .233 | 279 | .429 | 284 | .436 | 61.8 | 3.5 | 3.16 | 3.20 |
| Rich Hill* | SOI | sp | 27 | .706 | 472 | .278 | 324 | .435 | 336 | .451 | 83.1 | 4.3 | 3.94 | 3.93 |
| Shawn Hill | RMO | sp | 26 | .802 | 227 | .300 | 151 | .489 | 156 | .505 | 41.6 | 5.3 | 4.70 | 4.66 |
| Jason Hirsh | HAR | sp | 25 | .798 | 142 | .254 | 102 | .502 | 104 | .512 | 27.8 | 5.3 | 4.76 | 4.41 |
| Luke Hochevar | HAR | mr | 23 | .729 | 54 | .296 | 22 | .361 | 26 | .426 | 7.2 | 4.8 | 4.35 | 4.99 |
| Trevor Hoffman | GAR | cl | 39 | .556 | 183 | .240 | 86 | .347 | 86 | .347 | 18.1 | 2.6 | 2.30 | 1.63 |
| J.P. Howell* | CIO | sp | 24 | .847 | 157 | .318 | 127 | .520 | 131 | .537 | 39.6 | 6.6 | 6.01 | 5.54 |
| Bob Howry | GAR | mr | 33 | .863 | 53 | .302 | 41 | .532 | 42 | .545 | 12.4 | 6.3 | 5.81 | 6.18 |
| Tim Hudson | SOI | sp | 31 | .670 | 696 | .286 | 343 | .384 | 356 | .399 | 88.5 | 3.7 | 3.41 | 3.51 |
| Phil Hughes | NYD | sp | 21 | .672 | 225 | .209 | 141 | .434 | 144 | .443 | 30.5 | 3.3 | 3.09 | 2.97 |
| Philip Humber | BBG | mr | 24 | .947 | 38 | .316 | 25 | .595 | 25 | .595 | 8.6 | 8.6 | 7.45 | 5.67 |
| Jason Isringhausen | CEN | cl | 34 | .608 | 165 | .194 | 101 | .396 | 103 | .404 | 18.8 | 2.5 | 2.29 | 2.33 |
| Edwin Jackson | REN | sp | 23 | .780 | 426 | .284 | 294 | .481 | 299 | .489 | 82.6 | 5.3 | 4.83 | 4.63 |
| Chuck James* | FDH | sp | 25 | .730 | 152 | .243 | 98 | .469 | 98 | .469 | 25.3 | 4.6 | 4.24 | 3.82 |
| Casey Janssen | TEW | mr | 25 | .664 | 245 | .269 | 124 | .397 | 126 | .404 | 31.2 | 3.7 | 3.44 | 3.22 |
| Bobby Jenks | TEW | cl | 26 | .489 | 201 | .279 | 71 | .266 | 72 | .270 | 14.8 | 1.9 | 1.71 | 1.56 |
| Jason Jennings | BRK | sp | 28 | .877 | 212 | .321 | 160 | .533 | 163 | .543 | 49.3 | 6.7 | 5.93 | 5.26 |
| Ubaldo Jimenez | CIO | sp | 23 | .841 | 184 | .326 | 148 | .516 | 154 | .537 | 43.2 | 6.3 | 5.81 | 5.59 |
| Jim Johnson | TEW | mr | 24 | 2.056 | 7 | .857 | 9 | 1.000 | 9 | 1.000 | 6.9 | 186.7 | 168.05 | 173.72 |
| Josh Johnson | BBG | sp | 23 | .966 | 48 | .438 | 39 | .574 | 39 | .574 | 14.3 | 9.2 | 8.27 | 8.27 |
| Randy Johnson* | GAR | sp | 43 | .816 | 138 | .297 | 119 | .500 | 127 | .534 | 33.7 | 5.3 | 4.82 | 4.71 |
| Todd Jones | CTW | cl | 39 | .682 | 136 | .265 | 69 | .418 | 69 | .418 | 15.3 | 3.3 | 2.99 | 3.12 |
| Jair Jurrjens | NEP | sp | 21 | .667 | 83 | .229 | 48 | .429 | 48 | .429 | 10.8 | 3.6 | 3.25 | 3.29 |
| Jeff Karstens | FDH | mr | 24 | 1.323 | 53 | .434 | 70 | .824 | 71 | .835 | 31.1 | 19.5 | 18.89 | 17.56 |
| Scott Kazmir* | HAR | sp | 23 | .708 | 519 | .318 | 376 | .433 | 385 | .443 | 99.8 | 4.5 | 4.07 | 4.04 |
| Kyle Kendrick | CIN | sp | 22 | .701 | 403 | .243 | 211 | .422 | 222 | .444 | 51.4 | 3.7 | 3.45 | 3.48 |
| Ian Kennedy | BBG | sp | 22 | .470 | 40 | .225 | 22 | .306 | 22 | .306 | 3.8 | 1.8 | 1.69 | 1.52 |
| Byung-Hyun Kim | CTW | sp | 28 | .862 | 236 | .322 | 190 | .526 | 198 | .548 | 56.3 | 6.3 | 5.65 | 5.83 |
| Hong-Chih Kuo* | NYD | sp | 25 | .639 | 106 | .302 | 59 | .383 | 59 | .383 | 13.4 | 3.2 | 2.91 | 3.19 |
| John Lackey | GAR | sp | 28 | .654 | 633 | .272 | 361 | .393 | 373 | .406 | 84.6 | 3.3 | 3.00 | 2.96 |
| Aaron Laffey* | NYD | sp | 22 | .643 | 191 | .283 | 87 | .380 | 88 | .384 | 19.7 | 3.1 | 2.73 | 2.61 |
| John Lannan* | RYS | sp | 22 | .907 | 100 | .320 | 67 | .528 | 69 | .543 | 22.7 | 7.8 | 7.07 | 7.71 |
| Brandon League | ATM | mr | 24 | 1.053 | 37 | .568 | 28 | .549 | 28 | .549 | 12.2 | 12.6 | 10.95 | 12.25 |
| Cliff Lee* | BRK | sp | 28 | .931 | 252 | .290 | 223 | .595 | 227 | .605 | 69.5 | 7.6 | 6.84 | 6.54 |
| Jon Lester* | CIO | sp | 23 | .832 | 140 | .307 | 117 | .527 | 117 | .527 | 33.9 | 6.2 | 5.64 | 5.80 |
| Colby Lewis | BBG | mr | 27 | 1.084 | 131 | .443 | 118 | .631 | 121 | .647 | 47.0 | 11.9 | 10.28 | 10.22 |
| Jensen Lewis | BAR | mr | 23 | .488 | 12 | .250 | 6 | .316 | 6 | .316 | 1.1 | 2.0 | 1.92 | 1.19 |
| Brad Lidge | BRK | cl | 30 | .939 | 126 | .389 | 136 | .589 | 139 | .602 | 44.4 | 8.0 | 7.50 | 6.64 |
| Ted Lilly* | CIN | sp | 31 | .805 | 449 | .258 | 377 | .526 | 385 | .537 | 100.2 | 5.3 | 4.85 | 4.50 |
| Tim Lincecum | NYD | sp | 23 | .676 | 413 | .278 | 279 | .427 | 279 | .427 | 68.9 | 4.0 | 3.61 | 3.39 |
| Matt Lindstrom | PHI | mr | 27 | .516 | 200 | .225 | 88 | .307 | 92 | .321 | 16.9 | 2.1 | 1.90 | 2.05 |
| Scott Linebrink | ATM | mr | 30 | .928 | 182 | .357 | 140 | .565 | 140 | .565 | 46.3 | 8.0 | 7.21 | 8.05 |
| Jesse Litsch | REN | sp | 22 | .768 | 318 | .274 | 201 | .475 | 204 | .482 | 51.4 | 4.5 | 4.13 | 4.25 |
| Wes Littleton | BAR | mr | 24 | .632 | 132 | .220 | 64 | .372 | 69 | .401 | 16.2 | 3.5 | 3.25 | 3.02 |
| Bobby Livingston* | PHI | sp | 24 | 1.197 | 19 | .474 | 18 | .750 | 18 | .750 | 8.1 | 16.9 | 15.23 | 12.93 |
| Kameron Loe | FDH | sp | 25 | .712 | 417 | .285 | 238 | .432 | 243 | .441 | 61.6 | 4.2 | 3.87 | 3.82 |
| Kyle Lohse | FDH | sp | 28 | .753 | 520 | .304 | 308 | .445 | 315 | .455 | 89.3 | 5.1 | 4.62 | 4.39 |
| Braden Looper | CBB | sp | 32 | .742 | 597 | .273 | 348 | .453 | 354 | .460 | 95.1 | 4.8 | 4.33 | 4.17 |
| Javier Lopez* | RYS | mr | 29 | .537 | 101 | .178 | 47 | .331 | 50 | .352 | 8.8 | 2.2 | 1.96 | 1.94 |
| Rodrigo Lopez | CBB | sp | 31 | .855 | 284 | .310 | 194 | .532 | 194 | .532 | 56.6 | 6.0 | 5.46 | 5.02 |
| Derek Lowe | TEW | sp | 34 | .753 | 612 | .299 | 411 | .468 | 414 | .471 | 105.1 | 4.6 | 4.15 | 4.24 |
| Mark Lowe | HAR | mr | 24 | .481 | 10 | .300 | 4 | .267 | 4 | .267 | 1.1 | 2.8 | 2.32 | 1.79 |
| Brandon Lyon | FDH | mr | 27 | .736 | 216 | .306 | 118 | .437 | 119 | .441 | 33.9 | 4.9 | 4.42 | 3.99 |
| Greg Maddux | CBB | sp | 41 | .774 | 686 | .338 | 375 | .442 | 386 | .455 | 114.3 | 5.2 | 4.71 | 4.26 |
| Ryan Madson | BBG | mr | 26 | .733 | 182 | .319 | 102 | .429 | 104 | .437 | 29.9 | 4.9 | 4.51 | 4.08 |
| Ron Mahay* | NYD | mr | 36 | .682 | 169 | .231 | 120 | .448 | 121 | .451 | 25.5 | 3.7 | 3.34 | 3.93 |
| John Maine | TEW | sp | 26 | .802 | 500 | .278 | 398 | .513 | 400 | .515 | 106.7 | 5.3 | 4.80 | 4.61 |
| Shaun Marcum | PHI | sp | 25 | .794 | 428 | .276 | 311 | .501 | 314 | .506 | 80.7 | 4.9 | 4.44 | 4.49 |
| Carlos Marmol | SOI | mr | 24 | .523 | 160 | .269 | 101 | .332 | 102 | .336 | 20.8 | 2.5 | 2.27 | 2.19 |
| Mike Maroth* | CIO | sp | 29 | 1.163 | 420 | .376 | 409 | .710 | 415 | .720 | 157.7 | 12.9 | 11.27 | 11.08 |
| Jason Marquis | CIO | sp | 28 | .776 | 494 | .279 | 322 | .468 | 334 | .485 | 92.0 | 5.4 | 4.93 | 4.89 |
| Sean Marshall* | BBG | sp | 24 | .806 | 284 | .335 | 189 | .488 | 192 | .496 | 54.0 | 5.5 | 4.95 | 4.84 |
| Damaso Marte* | ATM | mr | 32 | .814 | 91 | .352 | 73 | .487 | 76 | .507 | 21.0 | 5.6 | 5.15 | 4.67 |
| Pedro Martinez | CEN | sp | 35 | .828 | 104 | .346 | 71 | .490 | 74 | .510 | 21.3 | 5.8 | 5.08 | 4.92 |
| Nick Masset | CIO | mr | 25 | .821 | 154 | .305 | 106 | .498 | 108 | .507 | 31.4 | 6.2 | 5.82 | 5.89 |
| Daisuke Matsuzaka | CEN | sp | 26 | .692 | 533 | .270 | 374 | .434 | 384 | .446 | 92.4 | 4.0 | 3.62 | 3.39 |
| Brandon McCarthy | BRK | sp | 23 | .879 | 345 | .310 | 260 | .538 | 265 | .549 | 82.0 | 7.0 | 6.42 | 5.90 |
| Dustin McGowan | NYD | sp | 25 | .579 | 531 | .239 | 271 | .357 | 275 | .362 | 57.8 | 2.7 | 2.41 | 2.04 |
| Gil Meche | RMO | sp | 28 | .712 | 170 | .282 | 111 | .439 | 112 | .443 | 28.6 | 4.3 | 4.01 | 4.33 |
| Luis Mendoza | GAR | sp | 23 | .605 | 60 | .267 | 27 | .360 | 27 | .360 | 5.9 | 2.7 | 2.50 | 2.36 |
| Cla Meredith | CBB | mr | 24 | .799 | 169 | .373 | 104 | .456 | 107 | .469 | 31.2 | 5.6 | 5.03 | 5.70 |
| Jose Mesa |   | mr | 41 | .819 | 179 | .291 | 116 | .500 | 119 | .513 | 35.2 | 6.2 | 5.39 | 4.88 |
| Dan Meyer* | BRK | sp | 25 | .909 | 68 | .324 | 50 | .575 | 50 | .575 | 14.7 | 6.6 | 6.06 | 4.88 |
| Andrew Miller* | BRK | sp | 22 | .919 | 210 | .348 | 187 | .562 | 193 | .580 | 61.5 | 8.3 | 7.66 | 8.05 |
| Justin Miller | CIN | mr | 29 | .720 | 139 | .295 | 108 | .470 | 108 | .470 | 24.8 | 3.9 | 3.50 | 3.17 |
| Trever Miller* | CIN | mr | 34 | .808 | 117 | .265 | 85 | .497 | 89 | .520 | 24.5 | 5.8 | 5.27 | 5.12 |
| Kevin Millwood | CTW | sp | 32 | .735 | 532 | .267 | 318 | .449 | 326 | .460 | 81.5 | 4.3 | 3.88 | 4.01 |
| Sergio Mitre | NYD | sp | 26 | .836 | 277 | .365 | 172 | .482 | 174 | .487 | 56.1 | 6.4 | 5.88 | 6.13 |
| Franklin Morales* | GAR | sp | 21 | .772 | 79 | .278 | 57 | .475 | 59 | .492 | 16.1 | 5.3 | 4.76 | 4.69 |
| Brandon Morrow | TEW | mr | 22 | .775 | 172 | .331 | 134 | .475 | 136 | .482 | 39.1 | 5.8 | 5.19 | 5.06 |
| Dustin Moseley | PHI | mr | 25 | .752 | 330 | .324 | 187 | .439 | 192 | .451 | 51.7 | 4.6 | 4.20 | 4.26 |
| Guillermo Mota | BRK | mr | 33 | .999 | 188 | .340 | 169 | .610 | 176 | .635 | 61.9 | 10.3 | 9.29 | 9.12 |
| Jamie Moyer* | REN | sp | 44 | .878 | 630 | .348 | 471 | .535 | 477 | .542 | 150.0 | 6.9 | 6.25 | 5.82 |
| Peter Moylan | RMO | mr | 28 | .860 | 235 | .336 | 164 | .492 | 177 | .532 | 51.8 | 6.2 | 5.57 | 5.88 |
| Edward Mujica | ATM | mr | 23 | .887 | 37 | .297 | 28 | .583 | 28 | .583 | 8.5 | 7.0 | 6.27 | 5.46 |
| Mike Mussina | PHI | sp | 38 | .895 | 396 | .354 | 297 | .550 | 300 | .556 | 93.9 | 6.9 | 6.45 | 5.95 |
| Brett Myers | PHI | cl | 26 | .729 | 150 | .327 | 124 | .466 | 124 | .466 | 32.4 | 4.8 | 4.30 | 4.08 |
| Joe Nathan | CEN | cl | 32 | .544 | 174 | .218 | 93 | .339 | 97 | .354 | 18.6 | 2.3 | 2.12 | 1.75 |
| Pat Neshek | NYD | mr | 26 | .504 | 153 | .150 | 91 | .338 | 94 | .349 | 15.2 | 1.9 | 1.72 | 1.45 |
| Ricky Nolasco | ATM | sp | 24 | 1.071 | 74 | .459 | 63 | .624 | 63 | .624 | 27.8 | 14.2 | 12.28 | 12.23 |
| Leo Nunez | ATM | mr | 23 | .775 | 101 | .218 | 74 | .507 | 75 | .514 | 18.9 | 4.7 | 4.29 | 3.65 |
| Eric O'Flaherty* | RYS | mr | 22 | .865 | 140 | .371 | 96 | .492 | 101 | .518 | 32.2 | 7.1 | 6.42 | 6.05 |
| Ross Ohlendorf | RYS | mr | 24 | .645 | 13 | .231 | 12 | .462 | 12 | .462 | 3.2 | 5.8 | 5.61 | 5.83 |
| Will Ohman* | NEP | mr | 29 | .715 | 129 | .333 | 75 | .426 | 75 | .426 | 20.9 | 4.7 | 4.26 | 3.80 |
| Hideki Okajima* | CBB | mr | 31 | .478 | 194 | .206 | 86 | .299 | 88 | .306 | 14.3 | 1.6 | 1.53 | 1.33 |
| Darren Oliver* | BBG | mr | 36 | .716 | 178 | .275 | 121 | .448 | 122 | .452 | 30.7 | 4.3 | 3.87 | 3.67 |
| Scott Olsen* | CIO | sp | 23 | .915 | 166 | .367 | 129 | .549 | 130 | .553 | 42.1 | 7.7 | 6.91 | 7.87 |
| Ramon Ortiz | FDH | mr | 34 | .863 | 375 | .301 | 260 | .533 | 265 | .543 | 79.6 | 6.4 | 5.78 | 5.13 |
| Roy Oswalt | CEN | sp | 29 | .698 | 654 | .309 | 368 | .412 | 378 | .423 | 96.2 | 4.1 | 3.65 | 3.58 |
| Akinori Otsuka | CEN | mr | 35 | .502 | 108 | .213 | 44 | .310 | 44 | .310 | 8.7 | 2.2 | 1.98 | 1.76 |
| Micah Owings | SOI | sp | 24 | .907 | 66 | .318 | 54 | .587 | 54 | .587 | 15.0 | 6.3 | 5.79 | 5.64 |
| Vicente Padilla | CIN | sp | 29 | .543 | 25 | .200 | 11 | .344 | 11 | .344 | 1.5 | 1.5 | 1.32 | 2.06 |
| Jonathan Papelbon | HAR | cl | 26 | .491 | 130 | .215 | 76 | .317 | 78 | .325 | 12.8 | 1.8 | 1.61 | 1.35 |
| Manny Parra* | NYD | mr | 24 | .835 | 87 | .391 | 65 | .485 | 66 | .493 | 20.7 | 6.9 | 6.13 | 6.98 |
| Troy Patton* | TEW | sp | 21 | .846 | 34 | .324 | 23 | .489 | 24 | .511 | 7.6 | 6.9 | 5.98 | 6.66 |
| Carl Pavano | NEP | sp | 31 | .688 | 48 | .208 | 27 | .450 | 27 | .450 | 5.8 | 3.4 | 3.05 | 3.12 |
| Jake Peavy | SOI | sp | 26 | .656 | 593 | .295 | 369 | .401 | 374 | .407 | 88.9 | 3.6 | 3.27 | 3.05 |
| Mike Pelfrey | REN | sp | 23 | .864 | 260 | .315 | 183 | .504 | 192 | .529 | 60.1 | 7.1 | 6.32 | 6.52 |
| Ramon Antonio Pena | GAR | mr | 25 | .700 | 156 | .288 | 100 | .431 | 103 | .444 | 24.7 | 4.0 | 3.59 | 3.63 |
| Brad Penny | RMO | sp | 29 | .734 | 613 | .330 | 353 | .430 | 359 | .438 | 97.3 | 4.6 | 4.24 | 4.30 |
| Joel Peralta | BBG | mr | 31 | .718 | 281 | .278 | 166 | .438 | 167 | .441 | 43.1 | 4.2 | 3.74 | 3.35 |
| Troy Percival | BAR | mr | 37 | .585 | 105 | .229 | 57 | .356 | 59 | .369 | 13.1 | 2.9 | 2.64 | 2.14 |
| Odalis Perez* | CIO | sp | 30 | .804 | 191 | .325 | 120 | .486 | 120 | .486 | 33.1 | 5.3 | 4.73 | 4.88 |
| Oliver Perez* | RMO | sp | 25 | 1.583 | 6 | .500 | 11 | .917 | 12 | 1.000 | 5.7 | 30.8 | 27.73 | 26.50 |
| Rafael Perez* | SOI | mr | 25 | .623 | 153 | .261 | 100 | .394 | 102 | .402 | 22.2 | 3.2 | 2.93 | 2.87 |
| Glen Perkins* | ATM | mr | 24 | .606 | 74 | .297 | 37 | .356 | 37 | .356 | 7.7 | 2.7 | 2.43 | 2.80 |
| Yusmeiro Petit | RYS | sp | 22 | .834 | 178 | .287 | 137 | .537 | 137 | .537 | 37.4 | 5.7 | 5.32 | 4.96 |
| Andy Pettitte* | HAR | sp | 35 | .854 | 622 | .357 | 407 | .508 | 409 | .511 | 127.9 | 6.5 | 5.88 | 5.76 |
| Joel Pineiro | BRK | mr | 28 | .814 | 239 | .297 | 170 | .504 | 174 | .516 | 49.1 | 5.8 | 5.35 | 5.06 |
| Scott Proctor | BBG | mr | 30 | .834 | 126 | .302 | 95 | .516 | 97 | .527 | 28.7 | 6.5 | 5.87 | 5.92 |
| J.J. Putz | HAR | cl | 30 | .444 | 158 | .184 | 77 | .283 | 79 | .290 | 10.9 | 1.3 | 1.17 | 1.20 |
| Chad Qualls | PHI | mr | 28 | .716 | 215 | .312 | 136 | .413 | 144 | .438 | 37.1 | 4.4 | 3.95 | 4.61 |
| Edwar Ramirez | TEW | mr | 26 | .722 | 5 | .000 | 5 | .556 | 5 | .556 | 0.9 | 3.7 | 3.29 | 2.97 |
| Horacio Ramirez* | CIO | sp | 27 | .897 | 349 | .304 | 256 | .549 | 260 | .558 | 75.0 | 6.6 | 6.02 | 6.33 |
| Ramon Ramirez | PHI | mr | 25 | .855 | 58 | .345 | 45 | .536 | 45 | .536 | 15.3 | 7.6 | 7.00 | 5.61 |
| Jon Rauch | CIN | mr | 28 | .585 | 228 | .241 | 107 | .354 | 108 | .358 | 23.0 | 2.7 | 2.42 | 2.26 |
| Chris Ray | NYD | cl | 25 | .530 | 56 | .161 | 28 | .341 | 29 | .354 | 5.0 | 2.1 | 1.96 | 1.74 |
| Tim Redding | CEN | sp | 29 | .557 | 25 | .240 | 10 | .313 | 11 | .344 | 1.9 | 2.1 | 1.87 | 1.99 |
| Al Reyes | CBB | cl | 37 | .694 | 150 | .233 | 122 | .452 | 125 | .463 | 29.5 | 4.0 | 3.64 | 3.01 |
| Anthony Reyes | FDH | sp | 25 | .708 | 125 | .240 | 81 | .448 | 83 | .459 | 21.1 | 4.5 | 4.14 | 3.39 |
| David Riske | CBB | mr | 30 | .668 | 87 | .276 | 55 | .417 | 56 | .424 | 14.1 | 4.0 | 3.69 | 3.19 |
| Mariano Rivera | CTW | cl | 37 | .558 | 165 | .248 | 79 | .326 | 84 | .347 | 17.7 | 2.6 | 2.36 | 2.22 |
| Saul Rivera | PHI | mr | 29 | .898 | 205 | .351 | 162 | .542 | 164 | .548 | 53.4 | 8.1 | 7.21 | 7.22 |
| Nate Robertson* |   | sp | 29 | .827 | 276 | .326 | 180 | .489 | 184 | .500 | 55.8 | 6.1 | 5.45 | 5.44 |
| Fernando Rodney | BBG | mr | 30 | .773 | 145 | .331 | 111 | .483 | 112 | .487 | 32.2 | 5.6 | 5.08 | 4.45 |
| Francisco Rodriguez |   | cl | 25 | .581 | 155 | .290 | 109 | .372 | 110 | .375 | 24.2 | 3.0 | 2.76 | 2.33 |
| Wandy Rodriguez* | ATM | sp | 28 | .851 | 438 | .331 | 341 | .526 | 344 | .531 | 101.9 | 6.3 | 5.72 | 5.44 |
| Kenny Rogers* | CBB | sp | 42 | .747 | 215 | .288 | 135 | .461 | 136 | .464 | 35.9 | 4.7 | 4.30 | 4.26 |
| J.C. Romero* | PHI | mr | 31 | .666 | 171 | .205 | 105 | .432 | 107 | .440 | 24.0 | 3.8 | 3.44 | 3.11 |
| Ryan Rowland-Smith* | NEP | mr | 24 | .815 | 85 | .376 | 68 | .500 | 68 | .500 | 19.2 | 5.6 | 5.07 | 5.20 |
| B.J. Ryan* | CTW | cl | 31 | 1.435 | 21 | .429 | 25 | .926 | 25 | .926 | 11.0 | 21.2 | 19.04 | 18.29 |
| Kirk Saarloos | REN | mr | 28 | 1.038 | 84 | .357 | 78 | .650 | 78 | .650 | 27.5 | 10.0 | 9.28 | 9.24 |
| C.C. Sabathia* | ATM | sp | 26 | .769 | 673 | .300 | 459 | .480 | 467 | .488 | 120.3 | 4.7 | 4.23 | 3.93 |
| Takashi Saito | GAR | cl | 37 | .658 | 140 | .214 | 105 | .432 | 107 | .440 | 23.2 | 3.5 | 3.11 | 2.98 |
| Chris Sampson | TEW | sp | 29 | .807 | 344 | .308 | 208 | .480 | 212 | .490 | 61.9 | 5.7 | 5.20 | 5.42 |
| Brian Sanches | BRK | mr | 28 | 1.107 | 47 | .170 | 58 | .725 | 58 | .725 | 17.1 | 8.7 | 7.85 | 7.59 |
| Anibal Sanchez | CIN | sp | 23 | .914 | 98 | .327 | 71 | .538 | 73 | .553 | 24.8 | 8.7 | 7.94 | 8.70 |
| Jonathan Sanchez* | RYS | mr | 24 | .941 | 137 | .423 | 134 | .558 | 137 | .571 | 44.1 | 8.0 | 7.10 | 7.58 |
| Ervin Santana | ATM | sp | 24 | .916 | 374 | .345 | 326 | .569 | 334 | .583 | 105.2 | 7.7 | 6.91 | 6.68 |
| Johan Santana* | GAR | sp | 28 | .739 | 542 | .264 | 418 | .480 | 424 | .487 | 101.3 | 4.2 | 3.85 | 3.53 |
| Dennis Sarfate | GAR | mr | 26 | .664 | 8 | .375 | 4 | .364 | 4 | .364 | 0.9 | 3.0 | 2.70 | 4.24 |
| Joe Saunders* | RMO | sp | 26 | .642 | 72 | .264 | 35 | .393 | 35 | .393 | 7.7 | 3.1 | 2.81 | 2.70 |
| Curt Schilling | CEN | sp | 40 | .671 | 494 | .249 | 282 | .416 | 287 | .423 | 68.5 | 3.6 | 3.29 | 2.87 |
| Chris Schroder | TEW | mr | 28 | .639 | 143 | .273 | 77 | .376 | 81 | .395 | 19.9 | 3.7 | 3.38 | 2.89 |
| Bobby Seay* | RYS | mr | 29 | .823 | 114 | .342 | 76 | .484 | 78 | .497 | 24.8 | 6.5 | 5.84 | 5.21 |
| Ben Sheets | TEW | sp | 28 | .744 | 434 | .272 | 301 | .470 | 305 | .477 | 81.1 | 4.8 | 4.31 | 4.10 |
| George Sherrill* | SOI | mr | 30 | .509 | 123 | .260 | 59 | .306 | 60 | .311 | 12.2 | 2.3 | 2.08 | 2.06 |
| James Shields | ATM | sp | 25 | .725 | 446 | .283 | 301 | .454 | 309 | .466 | 79.0 | 4.5 | 4.03 | 3.56 |
| Scot Shields | HAR | mr | 31 | .604 | 226 | .252 | 117 | .356 | 122 | .371 | 25.8 | 2.8 | 2.55 | 2.79 |
| Brian Shouse* | BRK | mr | 38 | .771 | 147 | .361 | 85 | .434 | 87 | .444 | 24.7 | 5.2 | 4.62 | 4.86 |
| Carlos Silva | TEW | sp | 28 | .657 | 277 | .274 | 138 | .395 | 138 | .395 | 34.5 | 3.6 | 3.24 | 3.01 |
| Jason Simontacchi | CTW | sp | 33 | .933 | 251 | .315 | 204 | .591 | 208 | .603 | 63.2 | 7.4 | 6.73 | 6.41 |
| Kevin Slowey | REN | sp | 23 | .854 | 230 | .330 | 168 | .530 | 169 | .533 | 50.8 | 6.4 | 5.72 | 5.12 |
| Joe Smith | CTW | mr | 23 | .810 | 101 | .337 | 79 | .470 | 84 | .500 | 24.5 | 6.3 | 5.52 | 5.74 |
| John Smoltz | BAR | sp | 40 | .721 | 558 | .292 | 374 | .457 | 376 | .460 | 95.0 | 4.3 | 3.84 | 3.37 |
| Ian Snell | RMO | sp | 25 | .699 | 143 | .259 | 95 | .440 | 96 | .444 | 23.0 | 4.0 | 3.56 | 3.54 |
| Kyle Snyder | NYD | mr | 29 | .780 | 42 | .238 | 37 | .514 | 37 | .514 | 9.2 | 5.1 | 4.68 | 5.36 |
| Andy Sonnanstine | NEP | sp | 24 | .821 | 379 | .325 | 278 | .504 | 287 | .520 | 81.3 | 5.7 | 5.13 | 4.66 |
| Joakim Soria |   | cl | 23 | .466 | 185 | .178 | 85 | .295 | 88 | .306 | 14.4 | 1.7 | 1.48 | 1.29 |
| Rafael Soriano | GAR | mr | 27 | .620 | 183 | .219 | 115 | .411 | 115 | .411 | 22.5 | 2.7 | 2.48 | 2.31 |
| Jorge Sosa | NYD | mr | 30 | .732 | 256 | .273 | 159 | .450 | 163 | .462 | 42.6 | 4.8 | 4.26 | 4.08 |
| Justin Speier | RMO | mr | 33 | .676 | 117 | .265 | 75 | .408 | 80 | .435 | 19.4 | 3.9 | 3.53 | 2.71 |
| Russ Springer | HAR | mr | 38 | .563 | 185 | .216 | 94 | .347 | 97 | .358 | 20.7 | 2.7 | 2.47 | 2.10 |
| Tim Stauffer | REN | sp | 25 | 1.284 | 29 | .345 | 38 | .809 | 39 | .830 | 14.8 | 15.3 | 13.81 | 16.44 |
| Mitch Stetter* | RYS | mr | 26 | 1.313 | 11 | .364 | 10 | .625 | 13 | .813 | 5.0 | 16.9 | 15.25 | 18.93 |
| Huston Street |   | cl | 23 | .592 | 97 | .289 | 57 | .358 | 57 | .358 | 13.0 | 3.0 | 2.65 | 2.43 |
| Eric Stults* | REN | mr | 27 | .779 | 62 | .306 | 41 | .477 | 41 | .477 | 11.3 | 5.2 | 4.41 | 4.18 |
| Jeff Suppan | BBG | sp | 32 | .849 | 589 | .328 | 380 | .499 | 392 | .514 | 118.5 | 6.3 | 5.68 | 5.35 |
| Brian Tallet* | BAR | mr | 29 | .608 | 186 | .237 | 104 | .371 | 109 | .389 | 23.4 | 3.0 | 2.70 | 2.44 |
| Taylor Tankersley* | HAR | mr | 24 | 1.140 | 34 | .382 | 41 | .719 | 41 | .719 | 15.9 | 13.4 | 12.10 | 12.85 |
| Julian Tavarez | CTW | sp | 34 | .855 | 269 | .312 | 187 | .527 | 190 | .535 | 53.0 | 5.8 | 5.21 | 5.19 |
| Robinson Tejeda | FDH | sp | 25 | .891 | 300 | .297 | 251 | .550 | 256 | .561 | 82.0 | 7.6 | 6.95 | 6.52 |
| Joe Thatcher* | BBG | mr | 25 | .469 | 53 | .151 | 22 | .314 | 22 | .314 | 3.2 | 1.5 | 1.36 | 1.05 |
| Brad Thompson | CTW | mr | 25 | .898 | 366 | .284 | 266 | .548 | 275 | .567 | 79.0 | 6.7 | 6.02 | 6.44 |
| Matt Thornton* | CIO | mr | 30 | .822 | 132 | .288 | 104 | .520 | 105 | .525 | 28.5 | 5.6 | 4.99 | 4.44 |
| Mike Timlin | CEN | mr | 41 | .631 | 87 | .184 | 42 | .412 | 42 | .412 | 8.5 | 2.8 | 2.68 | 2.59 |
| Brett Tomko | RYS | mr | 34 | .871 | 208 | .351 | 151 | .528 | 152 | .531 | 49.3 | 7.2 | 6.77 | 6.39 |
| Salomon Torres | PHI | mr | 35 | .572 | 26 | .346 | 9 | .281 | 9 | .281 | 2.7 | 3.1 | 2.83 | 2.76 |
| Josh Towers | CIO | sp | 30 | .742 | 26 | .462 | 14 | .378 | 14 | .378 | 4.5 | 5.1 | 4.36 | 5.15 |
| Steve Trachsel | FDH | sp | 36 | .860 | 211 | .303 | 139 | .527 | 139 | .527 | 40.9 | 6.2 | 5.62 | 5.83 |
| Derrick Turnbow | CIN | mr | 29 | .610 | 137 | .255 | 95 | .396 | 96 | .400 | 20.3 | 3.2 | 2.85 | 2.88 |
| Jose Valverde | SOI | cl | 27 | .702 | 161 | .292 | 125 | .448 | 126 | .452 | 32.6 | 4.5 | 4.10 | 3.89 |
| John Van Benschoten | CIO | sp | 27 | 1.102 | 140 | .393 | 137 | .643 | 144 | .676 | 53.9 | 12.9 | 11.59 | 12.18 |
| Rick VandenHurk | CTW | sp | 22 | .935 | 222 | .365 | 210 | .582 | 213 | .590 | 70.0 | 8.7 | 7.91 | 7.69 |
| Claudio Vargas | BRK | sp | 29 | .884 | 438 | .347 | 333 | .533 | 337 | .539 | 108.8 | 7.5 | 6.72 | 6.67 |
| Jason Vargas* | REN | sp | 24 | .924 | 46 | .391 | 31 | .500 | 32 | .516 | 11.3 | 8.0 | 7.39 | 7.78 |
| Javier Vazquez | SOI | sp | 30 | .730 | 564 | .284 | 400 | .459 | 409 | .470 | 100.6 | 4.2 | 3.81 | 3.55 |
| Jose Veras | RYS | mr | 26 | .830 | 30 | .300 | 19 | .500 | 19 | .500 | 5.6 | 6.0 | 5.43 | 4.55 |
| Justin Verlander | CTW | sp | 24 | .694 | 471 | .287 | 288 | .415 | 301 | .434 | 74.7 | 4.1 | 3.67 | 3.68 |
| Carlos Villanueva | CIN | mr | 23 | .745 | 315 | .232 | 237 | .481 | 241 | .489 | 60.5 | 4.7 | 4.18 | 3.86 |
| Oscar Villarreal | HAR | mr | 25 | .473 | 46 | .217 | 15 | .278 | 15 | .278 | 2.7 | 1.7 | 1.58 | 1.15 |
| Ron Villone* | CIN | mr | 37 | .946 | 68 | .250 | 63 | .618 | 65 | .637 | 19.4 | 7.8 | 7.15 | 7.10 |
| Luis Vizcaino | PHI | mr | 32 | .641 | 28 | .321 | 15 | .385 | 15 | .385 | 3.3 | 3.1 | 2.84 | 2.92 |
| Edinson Volquez | BAR | sp | 23 | .827 | 88 | .273 | 70 | .511 | 73 | .533 | 20.2 | 5.7 | 5.16 | 5.46 |
| Billy Wagner* | CIN | cl | 35 | .728 | 146 | .349 | 103 | .433 | 106 | .445 | 27.2 | 4.6 | 3.99 | 4.36 |
| Adam Wainwright | BRK | sp | 25 | .742 | 529 | .295 | 326 | .452 | 330 | .458 | 85.6 | 4.5 | 4.06 | 3.98 |
| Tim Wakefield | CIN | sp | 40 | .719 | 616 | .271 | 355 | .447 | 359 | .452 | 93.5 | 4.4 | 4.01 | 3.45 |
| Jamie Walker* | CBB | mr | 35 | .764 | 212 | .321 | 123 | .456 | 123 | .456 | 36.2 | 5.5 | 4.94 | 4.67 |
| Tyler Walker | REN | mr | 31 | .382 | 9 | .111 | 3 | .273 | 3 | .273 | 0.4 | 1.2 | 1.25 | 0.77 |
| Chien-Ming Wang | RMO | sp | 27 | .738 | 676 | .293 | 373 | .435 | 384 | .448 | 96.0 | 4.2 | 3.83 | 4.02 |
| Jarrod Washburn* | NEP | sp | 32 | .779 | 679 | .297 | 419 | .473 | 425 | .480 | 121.5 | 5.4 | 4.82 | 4.44 |
| David Weathers | CEN | cl | 37 | .617 | 232 | .246 | 109 | .371 | 112 | .381 | 25.7 | 3.2 | 2.99 | 2.57 |
| Jeff Weaver | NEP | sp | 30 | .701 | 152 | .270 | 81 | .424 | 83 | .435 | 21.1 | 4.1 | 3.68 | 3.28 |
| Jered Weaver | BBG | sp | 24 | .837 | 475 | .356 | 328 | .507 | 330 | .510 | 101.6 | 6.3 | 5.60 | 5.37 |
| Brandon Webb | BAR | sp | 28 | .565 | 625 | .256 | 294 | .337 | 303 | .347 | 65.6 | 2.7 | 2.45 | 2.13 |
| Todd Wellemeyer | TEW | mr | 28 | .813 | 212 | .255 | 162 | .514 | 167 | .530 | 44.8 | 5.7 | 5.06 | 4.98 |
| David Wells* | CTW | sp | 44 | 1.025 | 369 | .377 | 306 | .634 | 307 | .636 | 110.9 | 10.4 | 9.49 | 9.09 |
| Kip Wells |   | sp | 30 | .942 | 51 | .353 | 36 | .537 | 37 | .552 | 13.3 | 8.5 | 7.52 | 6.34 |
| Jake Westbrook | ATM | sp | 29 | .728 | 397 | .282 | 240 | .443 | 244 | .450 | 62.4 | 4.3 | 3.85 | 3.98 |
| Dan Wheeler | NEP | mr | 29 | .785 | 196 | .337 | 153 | .497 | 153 | .497 | 40.8 | 5.0 | 4.42 | 3.83 |
| Sean White | BRK | mr | 26 | .864 | 92 | .250 | 74 | .540 | 78 | .569 | 20.3 | 6.0 | 5.49 | 5.98 |
| Woody Williams | TEW | sp | 40 | .744 | 171 | .257 | 104 | .452 | 107 | .465 | 27.8 | 4.6 | 4.17 | 3.89 |
| Dontrelle Willis* | REN | sp | 25 | .856 | 549 | .301 | 423 | .527 | 439 | .547 | 127.6 | 6.5 | 5.93 | 5.75 |
| Brian Wilson | ATM | cl | 25 | .615 | 55 | .218 | 30 | .385 | 31 | .397 | 6.4 | 3.1 | 2.72 | 2.57 |
| C.J. Wilson* | BBG | mr | 26 | .774 | 165 | .352 | 118 | .457 | 121 | .469 | 32.2 | 5.1 | 4.66 | 5.61 |
| Matt Wise | CIN | mr | 31 | .583 | 8 | .125 | 5 | .417 | 5 | .417 | 0.8 | 2.3 | 2.03 | 1.58 |
| Randy Wolf* | BRK | sp | 30 | .843 | 243 | .358 | 194 | .522 | 195 | .524 | 59.5 | 6.7 | 6.03 | 5.39 |
| Kerry Wood | RYS | mr | 30 | .671 | 53 | .283 | 38 | .442 | 38 | .442 | 9.0 | 4.2 | 3.71 | 3.24 |
| Jamey Wright | FDH | mr | 32 | .806 | 248 | .319 | 158 | .480 | 160 | .486 | 45.2 | 5.5 | 5.04 | 5.56 |
| Michael Wuertz | NEP | mr | 28 | .627 | 209 | .287 | 125 | .391 | 125 | .391 | 29.3 | 3.4 | 3.07 | 3.07 |
| Chris Young | REN | sp | 28 | .664 | 382 | .270 | 272 | .417 | 281 | .431 | 68.4 | 4.0 | 3.68 | 3.31 |
| Carlos Zambrano | CEN | sp | 26 | .690 | 591 | .279 | 355 | .411 | 369 | .428 | 91.1 | 4.0 | 3.66 | 3.70 |
| Barry Zito* | RYS | sp | 29 | .832 | 559 | .288 | 430 | .529 | 434 | .534 | 121.3 | 6.0 | 5.39 | 5.38 |
| Joel Zumaya | CBB | mr | 22 | .665 | 72 | .278 | 43 | .413 | 43 | .413 | 10.6 | 4.0 | 3.57 | 3.41 |
| Start |
| Name | Team | P | Age | GS | CG | CG% | SHO | QS | QS% | RS | RS/G | RL | RLS | RL% | PCH/G | STR% |
| David Aardsma | CIO | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 6 | .316 | 25.2 | .586 |
| Jeremy Accardo | GAR | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 7 | .350 | 19.1 | .622 |
| Manny Acosta | BAR | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 24.5 | .592 |
| Jeremy Affeldt* | RYS | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 | 23.9 | .578 |
| Jonathan Albaladejo | GAR | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 20.6 | .676 |
| Matt Albers | RYS | sp | 24 | 15 | 0 | .000 | 0 | 7 | .467 | 52 | 3.5 | 8 | 3 | .375 | 63.1 | .604 |
| Tony Armas | FDH | mr | 29 | 6 | 0 | .000 | 0 | 2 | .333 | 24 | 4.0 | 5 | 2 | .400 | 35.9 | .648 |
| Bronson Arroyo | PHI | sp | 30 | 33 | 1 | .030 | 1 | 15 | .455 | 172 | 5.2 | 25 | 13 | .520 | 88.3 | .633 |
| Scott Atchison | ATM | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 20.2 | .635 |
| Luis Ayala | RMO | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 | 20.3 | .629 |
| Brandon Backe | BAR | sp | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 29.0 | .586 |
| Mike Bacsik* | BRK | sp | 29 | 5 | 0 | .000 | 0 | 1 | .200 | 19 | 3.8 | 4 | 3 | .750 | 53.1 | .651 |
| Cha Seung Baek | HAR | sp | 27 | 14 | 0 | .000 | 0 | 7 | .500 | 82 | 5.9 | 5 | 1 | .200 | 86.9 | .678 |
| Danys Baez | CTW | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 0 | .000 | 19.1 | .592 |
| Homer Bailey | FDH | sp | 21 | 7 | 0 | .000 | 0 | 3 | .429 | 29 | 4.1 | 6 | 2 | .333 | 100.0 | .567 |
| Scott Baker | BRK | sp | 25 | 17 | 1 | .059 | 1 | 11 | .647 | 71 | 4.2 | 9 | 7 | .778 | 85.6 | .640 |
| John Bale* | CEN | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 19.5 | .692 |
| Grant Balfour | BBG | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 | 15.6 | .588 |
| Brian Bannister | NEP | sp | 26 | 21 | 1 | .048 | 0 | 14 | .667 | 64 | 3.0 | 12 | 2 | .167 | 58.2 | .650 |
| Miguel Batista | PHI | sp | 36 | 17 | 0 | .000 | 0 | 10 | .588 | 95 | 5.6 | 6 | 2 | .333 | 76.1 | .607 |
| Yorman Bazardo | NYD | mr | 22 | 4 | 0 | .000 | 0 | 2 | .500 | 24 | 6.0 | 1 | 1 | 1.000 | 92.3 | .642 |
| Josh Beckett | SOI | sp | 27 | 30 | 2 | .067 | 0 | 21 | .700 | 184 | 6.1 | 6 | 3 | .500 | 96.9 | .694 |
| Erik Bedard* | BAR | sp | 28 | 29 | 3 | .103 | 3 | 22 | .759 | 137 | 4.7 | 7 | 5 | .714 | 104.7 | .643 |
| Joe Beimel* | SOI | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 8.1 | .608 |
| Matt Belisle | FDH | sp | 27 | 27 | 0 | .000 | 0 | 17 | .630 | 100 | 3.7 | 19 | 5 | .263 | 73.1 | .644 |
| Heath Bell | NYD | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 2 | .200 | 24.7 | .604 |
| Jeff Bennett | REN | sp | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 20.7 | .570 |
| Joaquin Benoit | NEP | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 6 | .667 | 20.6 | .633 |
| Jason Bergmann | RYS | sp | 25 | 10 | 0 | .000 | 0 | 2 | .200 | 55 | 5.5 | 9 | 1 | .111 | 78.1 | .590 |
| Rafael Betancourt | BAR | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 16.9 | .721 |
| Chad Billingsley | RMO | mr | 22 | 22 | 0 | .000 | 0 | 12 | .545 | 125 | 5.7 | 16 | 4 | .250 | 69.7 | .595 |
| Nick Blackburn | REN | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 27.9 | .728 |
| Joe Blanton | HAR | sp | 26 | 34 | 3 | .088 | 3 | 20 | .588 | 188 | 5.5 | 15 | 5 | .333 | 91.6 | .676 |
| Jerry Blevins* | CTW | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 | 16.3 | .615 |
| Jeremy Bonderman | HAR | sp | 24 | 17 | 0 | .000 | 0 | 9 | .529 | 100 | 5.9 | 10 | 2 | .200 | 79.6 | .644 |
| Boof Bonser | CBB | sp | 25 | 7 | 0 | .000 | 0 | 2 | .286 | 20 | 2.9 | 5 | 1 | .200 | 81.9 | .594 |
| Joe Borowski | PHI | cl | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 18.6 | .653 |
| Blaine Boyer | CBB | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 19.3 | .578 |
| Dallas Braden* | RYS | sp | 23 | 8 | 0 | .000 | 0 | 1 | .125 | 45 | 5.6 | 8 | 5 | .625 | 52.7 | .596 |
| Chad Bradford | CEN | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 | 22.4 | .666 |
| Bill Bray* | FDH | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 18.5 | .662 |
| Chris Britton | BAR | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 14.8 | .676 |
| Lance Broadway | NYD | mr | 23 | 2 | 0 | .000 | 0 | 2 | 1.000 | 11 | 5.5 | 0 | 0 | .000 | 101.5 | .616 |
| Doug Brocail | TEW | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 1 | .059 | 19.2 | .621 |
| Andrew Brown | HAR | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 28.1 | .609 |
| Jonathan Broxton | NYD | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 6 | .333 | 23.7 | .634 |
| Brian Bruney | BRK | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 | 21.8 | .526 |
| Clay Buchholz | RYS | sp | 22 | 3 | 1 | .333 | 1 | 3 | 1.000 | 12 | 4.0 | 2 | 0 | .000 | 85.3 | .566 |
| Taylor Buchholz | TEW | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 6 | .316 | 22.2 | .650 |
| Mark Buehrle* | RMO | sp | 28 | 32 | 1 | .031 | 0 | 16 | .500 | 169 | 5.3 | 16 | 6 | .375 | 91.8 | .654 |
| Jason Bulger | NEP | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 | 54.5 | .606 |
| A.J. Burnett | CIN | sp | 30 | 27 | 0 | .000 | 0 | 18 | .667 | 136 | 5.0 | 16 | 5 | .313 | 78.9 | .614 |
| Brian Burres* | BRK | mr | 26 | 6 | 0 | .000 | 0 | 1 | .167 | 24 | 4.0 | 10 | 4 | .400 | 62.8 | .606 |
| Jared Burton | SOI | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 15.4 | .610 |
| Dave Bush | NEP | sp | 27 | 30 | 1 | .033 | 0 | 13 | .433 | 130 | 4.3 | 14 | 2 | .143 | 92.8 | .645 |
| Paul Byrd | NEP | sp | 36 | 10 | 1 | .100 | 0 | 4 | .400 | 33 | 3.3 | 3 | 0 | .000 | 83.6 | .696 |
| Tim Byrdak* | CIN | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 7 | .583 | 24.4 | .601 |
| Daniel Cabrera | BBG | sp | 26 | 24 | 0 | .000 | 0 | 8 | .333 | 102 | 4.3 | 19 | 7 | .368 | 80.6 | .597 |
| Matt Cain | CEN | sp | 22 | 33 | 0 | .000 | 0 | 19 | .576 | 201 | 6.1 | 18 | 6 | .333 | 93.8 | .597 |
| Kiko Calero | CIO | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 5 | .417 | 20.9 | .620 |
| Kevin Cameron | REN | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 5 | .313 | 23.5 | .611 |
| Shawn Camp | ATM | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 12 | .400 | 17.7 | .603 |
| Jorge Campillo | NEP | mr | 28 | 4 | 0 | .000 | 0 | 0 | .000 | 7 | 1.8 | 4 | 1 | .250 | 49.3 | .579 |
| Matt Capps | NYD | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 20.0 | .688 |
| Buddy Carlyle | REN | sp | 29 | 3 | 0 | .000 | 0 | 0 | .000 | 8 | 2.7 | 10 | 4 | .400 | 23.6 | .630 |
| Fausto Carmona | RMO | sp | 26 | 30 | 1 | .033 | 1 | 22 | .733 | 172 | 5.7 | 13 | 3 | .231 | 91.9 | .638 |
| Chris Carpenter | CIO | sp | 32 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 0 | 0 | .000 | 110.0 | .564 |
| Santiago Casilla | BBG | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 8 | .471 | 19.6 | .612 |
| Shawn Chacon | RMO | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 4.0 | .750 |
| Joba Chamberlain | BAR | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 21.3 | .634 |
| Bruce Chen* | REN | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 23.4 | .583 |
| Matt Chico* | CTW | sp | 24 | 18 | 1 | .056 | 0 | 7 | .389 | 50 | 2.8 | 20 | 9 | .450 | 71.3 | .591 |
| Randy Choate* | RYS | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 25.0 | .560 |
| Roger Clemens | HAR | sp | 44 | 17 | 0 | .000 | 0 | 10 | .588 | 101 | 5.9 | 9 | 3 | .333 | 96.6 | .623 |
| Tyler Clippard | BRK | sp | 22 | 7 | 0 | .000 | 0 | 1 | .143 | 32 | 4.6 | 7 | 2 | .286 | 74.1 | .557 |
| Todd Coffey | RYS | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 5 | .385 | 23.3 | .615 |
| Jesus Colome | CIN | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 29.1 | .623 |
| Bartolo Colon | REN | sp | 34 | 3 | 0 | .000 | 0 | 1 | .333 | 24 | 8.0 | 33 | 9 | .273 | 24.3 | .653 |
| Clay Condrey | ATM | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 | 19.8 | .619 |
| Jose Contreras | NEP | sp | 35 | 34 | 1 | .029 | 0 | 9 | .265 | 138 | 4.1 | 18 | 6 | .333 | 92.6 | .634 |
| Aaron Cook | CIN | sp | 28 | 21 | 0 | .000 | 0 | 7 | .333 | 112 | 5.3 | 22 | 8 | .364 | 75.0 | .641 |
| Chad Cordero | SOI | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 2 | .105 | 20.7 | .628 |
| Francisco Cordero | CIN | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 6 | .400 | 25.9 | .634 |
| Lance Cormier | REN | sp | 26 | 4 | 0 | .000 | 0 | 1 | .250 | 15 | 3.8 | 13 | 7 | .538 | 42.9 | .620 |
| Manny Corpas | RMO | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 | 16.1 | .662 |
| Kevin Correia | ATM | mr | 26 | 7 | 0 | .000 | 0 | 6 | .857 | 35 | 5.0 | 3 | 3 | 1.000 | 98.3 | .651 |
| Neal Cotts* | FDH | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 9 | .750 | 16.7 | .575 |
| Jesse Crain | TEW | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 18.2 | .655 |
| Juan Cruz | HAR | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 2 | .200 | 20.5 | .618 |
| John Danks* | BRK | sp | 22 | 21 | 0 | .000 | 0 | 5 | .238 | 109 | 5.2 | 12 | 2 | .167 | 92.6 | .620 |
| Kyle Davies | CIO | sp | 23 | 16 | 0 | .000 | 0 | 1 | .063 | 73 | 4.6 | 17 | 8 | .471 | 50.0 | .570 |
| Doug Davis* | RYS | sp | 31 | 23 | 0 | .000 | 0 | 7 | .304 | 89 | 3.9 | 25 | 6 | .240 | 63.7 | .592 |
| Jorge De La Rosa* | CIO | sp | 26 | 8 | 0 | .000 | 0 | 1 | .125 | 35 | 4.4 | 39 | 11 | .282 | 24.4 | .606 |
| Manny Delcarmen | HAR | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 | 21.2 | .619 |
| Ryan Dempster | BAR | cl | 30 | 6 | 0 | .000 | 0 | 0 | .000 | 31 | 5.2 | 11 | 5 | .455 | 25.9 | .581 |
| Ross Detwiler* | HAR | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 17.0 | .647 |
| Joey Devine | ATM | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 21.0 | .565 |
| Lenny DiNardo* | RYS | sp | 27 | 15 | 0 | .000 | 0 | 7 | .467 | 58 | 3.9 | 19 | 2 | .105 | 56.3 | .587 |
| Brendan Donnelly | GAR | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 16.6 | .694 |
| Octavio Dotel | FDH | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 17.1 | .613 |
| Scott Downs* | SOI | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 6 | .240 | 15.8 | .609 |
| Justin Duchscherer | BAR | mr | 29 | 2 | 0 | .000 | 0 | 0 | .000 | 9 | 4.5 | 3 | 1 | .333 | 19.8 | .620 |
| Zach Duke* | CTW | sp | 24 | 20 | 0 | .000 | 0 | 3 | .150 | 89 | 4.4 | 19 | 7 | .368 | 85.2 | .617 |
| Chad Durbin | RYS | sp | 29 | 17 | 0 | .000 | 0 | 10 | .588 | 79 | 4.6 | 12 | 2 | .167 | 72.6 | .601 |
| J.D. Durbin | BRK | sp | 25 | 9 | 0 | .000 | 0 | 4 | .444 | 31 | 3.4 | 11 | 7 | .636 | 86.7 | .580 |
| Adam Eaton | CIO | sp | 29 | 20 | 0 | .000 | 0 | 3 | .150 | 78 | 3.9 | 34 | 8 | .235 | 48.0 | .562 |
| Scott Elarton | CIO | sp | 31 | 6 | 0 | .000 | 0 | 1 | .167 | 41 | 6.8 | 9 | 5 | .556 | 40.5 | .557 |
| Alan Embree* | CBB | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 13.0 | .769 |
| Kelvim Escobar | GAR | sp | 31 | 30 | 2 | .067 | 2 | 15 | .500 | 198 | 6.6 | 15 | 6 | .400 | 99.2 | .615 |
| Scott Feldman | BBG | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 5 | .263 | 21.3 | .542 |
| Pedro Feliciano* | SOI | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 2 | .118 | 18.7 | .585 |
| Gavin Floyd | CIN | sp | 24 | 6 | 0 | .000 | 0 | 3 | .500 | 31 | 5.2 | 5 | 1 | .200 | 41.0 | .640 |
| Josh Fogg | BBG | sp | 30 | 17 | 1 | .059 | 1 | 4 | .235 | 81 | 4.8 | 15 | 3 | .200 | 69.5 | .611 |
| Casey Fossum* | CTW | mr | 29 | 14 | 0 | .000 | 0 | 2 | .143 | 38 | 2.7 | 19 | 10 | .526 | 69.4 | .623 |
| Jeff Francis* | GAR | sp | 26 | 34 | 1 | .029 | 0 | 17 | .500 | 197 | 5.8 | 20 | 7 | .350 | 93.7 | .637 |
| Frank Francisco | NEP | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 9 | .310 | 21.6 | .565 |
| Ryan Franklin | CBB | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 2 | .200 | 20.1 | .679 |
| Jason Frasor | RYS | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 | 17.4 | .596 |
| Brian Fuentes* | HAR | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 4 | .167 | 18.6 | .594 |
| Aaron Fultz* | PHI | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 21.3 | .580 |
| Kason Gabbard* | NYD | sp | 25 | 14 | 1 | .071 | 0 | 10 | .714 | 60 | 4.3 | 8 | 1 | .125 | 98.0 | .565 |
| Eric Gagne | CEN | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 5 | .714 | 23.3 | .618 |
| Armando Galarraga | NEP | mr | 25 | 2 | 0 | .000 | 0 | 0 | .000 | 8 | 4.0 | 0 | 0 | .000 | 93.5 | .561 |
| Yovani Gallardo | PHI | sp | 21 | 16 | 0 | .000 | 0 | 10 | .625 | 73 | 4.6 | 9 | 3 | .333 | 104.9 | .622 |
| Freddy Garcia | CTW | sp | 31 | 9 | 0 | .000 | 0 | 4 | .444 | 28 | 3.1 | 8 | 2 | .250 | 99.2 | .619 |
| Lee Gardner | PHI | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 1 | .048 | 16.8 | .630 |
| Jon Garland | BAR | sp | 27 | 26 | 2 | .077 | 1 | 17 | .654 | 148 | 5.7 | 13 | 2 | .154 | 82.2 | .657 |
| Matt Garza | TEW | sp | 23 | 11 | 0 | .000 | 0 | 6 | .545 | 64 | 5.8 | 12 | 6 | .500 | 102.3 | .580 |
| Chad Gaudin | ATM | sp | 24 | 8 | 0 | .000 | 0 | 4 | .500 | 44 | 5.5 | 4 | 0 | .000 | 64.1 | .628 |
| Geoff Geary | NEP | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 1 | .056 | 20.1 | .615 |
| Justin Germano | TEW | sp | 24 | 14 | 0 | .000 | 0 | 7 | .500 | 70 | 5.0 | 9 | 2 | .222 | 86.4 | .616 |
| Dan Giese | CBB | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 30.7 | .636 |
| Tom Glavine* | BBG | sp | 41 | 31 | 1 | .032 | 0 | 12 | .387 | 121 | 3.9 | 28 | 9 | .321 | 73.5 | .612 |
| Mike Gonzalez* | BAR | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 19.8 | .495 |
| Tom Gordon | REN | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 19.7 | .624 |
| Tom Gorzelanny* | GAR | sp | 24 | 19 | 2 | .105 | 1 | 11 | .579 | 124 | 6.5 | 11 | 6 | .545 | 96.6 | .611 |
| John Grabow* | RYS | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 7 | .412 | 25.2 | .631 |
| Sean Green | ATM | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 19.8 | .589 |
| Kevin Gregg | RYS | cl | 29 | 6 | 0 | .000 | 0 | 0 | .000 | 21 | 3.5 | 18 | 5 | .278 | 25.2 | .568 |
| Zack Greinke | ATM | mr | 23 | 17 | 0 | .000 | 0 | 7 | .412 | 85 | 5.0 | 12 | 4 | .333 | 61.0 | .638 |
| Jason Grilli | ATM | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 | 22.8 | .618 |
| Eddie Guardado* | CTW | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 22.8 | .676 |
| Matt Guerrier | BAR | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 6 | .333 | 17.6 | .651 |
| Jeremy Guthrie | BAR | sp | 28 | 28 | 2 | .071 | 2 | 16 | .571 | 196 | 7.0 | 15 | 6 | .400 | 86.8 | .657 |
| Angel Guzman | CIO | mr | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 38.9 | .584 |
| Roy Halladay | PHI | sp | 30 | 33 | 3 | .091 | 0 | 16 | .485 | 163 | 4.9 | 11 | 7 | .636 | 98.4 | .665 |
| Cole Hamels* | FDH | sp | 23 | 23 | 1 | .043 | 1 | 13 | .565 | 71 | 3.1 | 9 | 3 | .333 | 94.3 | .652 |
| Jason Hammel | REN | sp | 24 | 13 | 0 | .000 | 0 | 4 | .308 | 43 | 3.3 | 14 | 5 | .357 | 51.6 | .605 |
| Justin Hampson* | BAR | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 4 | .200 | 17.1 | .628 |
| Joel Hanrahan | BBG | sp | 25 | 10 | 0 | .000 | 0 | 1 | .100 | 38 | 3.8 | 10 | 5 | .500 | 60.6 | .559 |
| J.A. Happ* | RYS | sp | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 2 | 2 | 1.000 | 50.0 | .590 |
| Aaron Harang | CBB | sp | 29 | 34 | 2 | .059 | 0 | 26 | .765 | 134 | 3.9 | 15 | 5 | .333 | 106.4 | .660 |
| Rich Harden | BRK | sp | 25 | 3 | 0 | .000 | 0 | 2 | .667 | 13 | 4.3 | 0 | 0 | .000 | 62.5 | .600 |
| Dan Haren | CIO | sp | 26 | 34 | 0 | .000 | 0 | 12 | .353 | 132 | 3.9 | 18 | 4 | .222 | 64.1 | .664 |
| LaTroy Hawkins | RMO | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 | 19.6 | .624 |
| Aaron Heilman | GAR | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 23.2 | .634 |
| Mark Hendrickson* | NYD | mr | 33 | 8 | 2 | .250 | 1 | 3 | .375 | 27 | 3.4 | 1 | 1 | 1.000 | 75.0 | .652 |
| Brad Hennessey | CIN | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 19.5 | .621 |
| Clay Hensley | TEW | sp | 27 | 9 | 0 | .000 | 0 | 0 | .000 | 40 | 4.4 | 5 | 2 | .400 | 88.2 | .577 |
| Matt Herges | CBB | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 0 | .000 | 16.3 | .623 |
| Felix Hernandez | CBB | sp | 21 | 31 | 1 | .032 | 0 | 19 | .613 | 120 | 3.9 | 11 | 5 | .455 | 95.5 | .635 |
| Livan Hernandez | FDH | sp | 32 | 12 | 1 | .083 | 0 | 4 | .333 | 33 | 2.8 | 7 | 4 | .571 | 73.5 | .605 |
| Orlando Hernandez | NYD | sp | 37 | 27 | 0 | .000 | 0 | 14 | .519 | 138 | 5.1 | 18 | 5 | .278 | 91.4 | .604 |
| Rich Hill* | SOI | sp | 27 | 29 | 0 | .000 | 0 | 14 | .483 | 210 | 7.2 | 14 | 7 | .500 | 98.1 | .613 |
| Shawn Hill | RMO | sp | 26 | 2 | 0 | .000 | 0 | 0 | .000 | 1 | 0.5 | 14 | 2 | .143 | 21.3 | .622 |
| Jason Hirsh | HAR | sp | 25 | 9 | 0 | .000 | 0 | 5 | .556 | 51 | 5.7 | 2 | 0 | .000 | 81.6 | .612 |
| Luke Hochevar | HAR | mr | 23 | 2 | 0 | .000 | 0 | 2 | 1.000 | 15 | 7.5 | 3 | 0 | .000 | 97.5 | .621 |
| Trevor Hoffman | GAR | cl | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 | 18.2 | .670 |
| J.P. Howell* | CIO | sp | 24 | 3 | 0 | .000 | 0 | 1 | .333 | 9 | 3.0 | 9 | 0 | .000 | 26.1 | .622 |
| Bob Howry | GAR | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 20.5 | .632 |
| Tim Hudson | SOI | sp | 31 | 34 | 2 | .059 | 0 | 25 | .735 | 204 | 6.0 | 21 | 10 | .476 | 90.6 | .637 |
| Phil Hughes | NYD | sp | 21 | 14 | 1 | .071 | 1 | 10 | .714 | 101 | 7.2 | 4 | 1 | .250 | 84.9 | .608 |
| Philip Humber | BBG | mr | 24 | 1 | 0 | .000 | 0 | 1 | 1.000 | 2 | 2.0 | 0 | 0 | .000 | 47.7 | .594 |
| Jason Isringhausen | CEN | cl | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 4 | .167 | 18.6 | .596 |
| Edwin Jackson | REN | sp | 23 | 25 | 1 | .040 | 1 | 10 | .400 | 110 | 4.4 | 14 | 1 | .071 | 87.9 | .599 |
| Chuck James* | FDH | sp | 25 | 5 | 0 | .000 | 0 | 3 | .600 | 9 | 1.8 | 2 | 0 | .000 | 47.4 | .619 |
| Casey Janssen | TEW | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 5 | .278 | 18.9 | .630 |
| Bobby Jenks | TEW | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 18.0 | .692 |
| Jason Jennings | BRK | sp | 28 | 12 | 0 | .000 | 0 | 4 | .333 | 36 | 3.0 | 12 | 4 | .333 | 90.1 | .600 |
| Ubaldo Jimenez | CIO | sp | 23 | 7 | 0 | .000 | 0 | 2 | .286 | 51 | 7.3 | 14 | 4 | .286 | 44.8 | .572 |
| Jim Johnson | TEW | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 28.0 | .500 |
| Josh Johnson | BBG | sp | 23 | 3 | 0 | .000 | 0 | 0 | .000 | 12 | 4.0 | 2 | 1 | .500 | 80.7 | .620 |
| Randy Johnson* | GAR | sp | 43 | 8 | 0 | .000 | 0 | 3 | .375 | 58 | 7.3 | 3 | 0 | .000 | 74.5 | .677 |
| Todd Jones | CTW | cl | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 19.3 | .633 |
| Jair Jurrjens | NEP | sp | 21 | 4 | 0 | .000 | 0 | 3 | .750 | 23 | 5.8 | 0 | 0 | .000 | 92.8 | .631 |
| Jeff Karstens | FDH | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 4 | 1 | .250 | 25.2 | .582 |
| Scott Kazmir* | HAR | sp | 23 | 34 | 0 | .000 | 0 | 17 | .500 | 201 | 5.9 | 27 | 6 | .222 | 100.0 | .607 |
| Kyle Kendrick | CIN | sp | 22 | 20 | 0 | .000 | 0 | 10 | .500 | 87 | 4.3 | 16 | 5 | .313 | 71.2 | .653 |
| Ian Kennedy | BBG | sp | 22 | 3 | 0 | .000 | 0 | 1 | .333 | 9 | 3.0 | 2 | 1 | .500 | 77.8 | .601 |
| Byung-Hyun Kim | CTW | sp | 28 | 6 | 0 | .000 | 0 | 1 | .167 | 20 | 3.3 | 18 | 6 | .333 | 39.4 | .604 |
| Hong-Chih Kuo* | NYD | sp | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 12 | 2 | .167 | 20.4 | .624 |
| John Lackey | GAR | sp | 28 | 33 | 1 | .030 | 1 | 25 | .758 | 177 | 5.4 | 5 | 1 | .200 | 102.6 | .660 |
| Aaron Laffey* | NYD | sp | 22 | 9 | 0 | .000 | 0 | 6 | .667 | 41 | 4.6 | 4 | 2 | .500 | 85.1 | .667 |
| John Lannan* | RYS | sp | 22 | 4 | 1 | .250 | 1 | 1 | .250 | 19 | 4.8 | 0 | 0 | .000 | 108.8 | .584 |
| Brandon League | ATM | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 | 24.0 | .552 |
| Cliff Lee* | BRK | sp | 28 | 14 | 0 | .000 | 0 | 4 | .286 | 65 | 4.6 | 3 | 1 | .333 | 77.8 | .609 |
| Jon Lester* | CIO | sp | 23 | 3 | 0 | .000 | 0 | 0 | .000 | 16 | 5.3 | 11 | 3 | .273 | 31.0 | .599 |
| Colby Lewis | BBG | mr | 27 | 5 | 0 | .000 | 0 | 2 | .400 | 24 | 4.8 | 6 | 0 | .000 | 60.7 | .626 |
| Jensen Lewis | BAR | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 26.3 | .595 |
| Brad Lidge | BRK | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 9 | .429 | 18.7 | .609 |
| Ted Lilly* | CIN | sp | 31 | 31 | 1 | .032 | 0 | 16 | .516 | 156 | 5.0 | 16 | 3 | .188 | 79.7 | .645 |
| Tim Lincecum | NYD | sp | 23 | 26 | 0 | .000 | 0 | 12 | .462 | 143 | 5.5 | 13 | 2 | .154 | 99.7 | .597 |
| Matt Lindstrom | PHI | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 8 | .320 | 17.6 | .619 |
| Scott Linebrink | ATM | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 6 | .333 | 19.0 | .607 |
| Jesse Litsch | REN | sp | 22 | 14 | 2 | .143 | 0 | 7 | .500 | 51 | 3.6 | 12 | 4 | .333 | 78.8 | .617 |
| Wes Littleton | BAR | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 26.3 | .636 |
| Bobby Livingston* | PHI | sp | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 7 | 7.0 | 2 | 0 | .000 | 87.0 | .667 |
| Kameron Loe | FDH | sp | 25 | 20 | 1 | .050 | 1 | 13 | .650 | 73 | 3.7 | 9 | 3 | .333 | 66.0 | .610 |
| Kyle Lohse | FDH | sp | 28 | 27 | 0 | .000 | 0 | 15 | .556 | 79 | 2.9 | 16 | 6 | .375 | 86.1 | .623 |
| Braden Looper | CBB | sp | 32 | 28 | 2 | .071 | 2 | 14 | .500 | 156 | 5.6 | 15 | 6 | .400 | 97.1 | .631 |
| Javier Lopez* | RYS | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 5 | .500 | 14.6 | .586 |
| Rodrigo Lopez | CBB | sp | 31 | 14 | 0 | .000 | 0 | 7 | .500 | 54 | 3.9 | 8 | 1 | .125 | 93.1 | .654 |
| Derek Lowe | TEW | sp | 34 | 33 | 1 | .030 | 1 | 19 | .576 | 197 | 6.0 | 17 | 4 | .235 | 99.7 | .621 |
| Mark Lowe | HAR | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 50.0 | .640 |
| Brandon Lyon | FDH | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 5 | .313 | 21.0 | .632 |
| Greg Maddux | CBB | sp | 41 | 34 | 0 | .000 | 0 | 15 | .441 | 161 | 4.7 | 12 | 4 | .333 | 82.9 | .702 |
| Ryan Madson | BBG | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 21.8 | .616 |
| Ron Mahay* | NYD | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 7 | .318 | 24.0 | .545 |
| John Maine | TEW | sp | 26 | 33 | 1 | .030 | 0 | 13 | .394 | 155 | 4.7 | 21 | 9 | .429 | 88.6 | .613 |
| Shaun Marcum | PHI | sp | 25 | 26 | 0 | .000 | 0 | 14 | .538 | 105 | 4.0 | 12 | 6 | .500 | 85.1 | .633 |
| Carlos Marmol | SOI | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 10 | .556 | 20.5 | .595 |
| Mike Maroth* | CIO | sp | 29 | 10 | 0 | .000 | 0 | 0 | .000 | 28 | 2.8 | 43 | 14 | .326 | 26.9 | .598 |
| Jason Marquis | CIO | sp | 28 | 29 | 0 | .000 | 0 | 7 | .241 | 106 | 3.7 | 34 | 14 | .412 | 64.8 | .584 |
| Sean Marshall* | BBG | sp | 24 | 14 | 0 | .000 | 0 | 8 | .571 | 74 | 5.3 | 10 | 3 | .300 | 70.6 | .614 |
| Damaso Marte* | ATM | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 6 | .545 | 21.4 | .611 |
| Pedro Martinez | CEN | sp | 35 | 4 | 0 | .000 | 0 | 3 | .750 | 17 | 4.3 | 5 | 1 | .200 | 53.7 | .637 |
| Nick Masset | CIO | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 9 | .321 | 21.6 | .584 |
| Daisuke Matsuzaka | CEN | sp | 26 | 33 | 3 | .091 | 1 | 21 | .636 | 186 | 5.6 | 16 | 3 | .188 | 99.5 | .618 |
| Brandon McCarthy | BRK | sp | 23 | 12 | 0 | .000 | 0 | 6 | .500 | 62 | 5.2 | 19 | 2 | .105 | 39.7 | .576 |
| Dustin McGowan | NYD | sp | 25 | 29 | 0 | .000 | 0 | 24 | .828 | 143 | 4.9 | 12 | 2 | .167 | 95.9 | .634 |
| Gil Meche | RMO | sp | 28 | 10 | 0 | .000 | 0 | 7 | .700 | 58 | 5.8 | 10 | 2 | .200 | 89.9 | .622 |
| Luis Mendoza | GAR | sp | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 26.4 | .672 |
| Cla Meredith | CBB | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 21 | 6 | .286 | 19.6 | .619 |
| Jose Mesa |   | mr | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 12 | .750 | 17.1 | .597 |
| Dan Meyer* | BRK | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 24.1 | .599 |
| Andrew Miller* | BRK | sp | 22 | 3 | 0 | .000 | 0 | 1 | .333 | 6 | 2.0 | 26 | 6 | .231 | 30.7 | .564 |
| Justin Miller | CIN | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 | 26.5 | .652 |
| Trever Miller* | CIN | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 | 18.3 | .576 |
| Kevin Millwood | CTW | sp | 32 | 22 | 4 | .182 | 3 | 9 | .409 | 110 | 5.0 | 7 | 4 | .571 | 72.2 | .628 |
| Sergio Mitre | NYD | sp | 26 | 7 | 1 | .143 | 1 | 1 | .143 | 34 | 4.9 | 13 | 1 | .077 | 34.0 | .627 |
| Franklin Morales* | GAR | sp | 21 | 5 | 0 | .000 | 0 | 0 | .000 | 27 | 5.4 | 4 | 2 | .500 | 93.6 | .592 |
| Brandon Morrow | TEW | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 6 | .250 | 22.0 | .558 |
| Dustin Moseley | PHI | mr | 25 | 15 | 1 | .067 | 0 | 11 | .733 | 82 | 5.5 | 8 | 1 | .125 | 101.7 | .650 |
| Guillermo Mota | BRK | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 8 | .333 | 18.2 | .591 |
| Jamie Moyer* | REN | sp | 44 | 33 | 1 | .030 | 0 | 11 | .333 | 138 | 4.2 | 16 | 7 | .438 | 95.6 | .635 |
| Peter Moylan | RMO | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 10 | .455 | 18.3 | .634 |
| Edward Mujica | ATM | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 16.3 | .669 |
| Mike Mussina | PHI | sp | 38 | 21 | 0 | .000 | 0 | 8 | .381 | 99 | 4.7 | 16 | 4 | .250 | 84.6 | .677 |
| Brett Myers | PHI | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 6 | .250 | 20.3 | .609 |
| Joe Nathan | CEN | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 1 | .100 | 17.5 | .664 |
| Pat Neshek | NYD | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 22.7 | .645 |
| Ricky Nolasco | ATM | sp | 24 | 3 | 0 | .000 | 0 | 0 | .000 | 16 | 5.3 | 7 | 2 | .286 | 41.4 | .619 |
| Leo Nunez | ATM | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 27.0 | .628 |
| Eric O'Flaherty* | RYS | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 7 | .292 | 19.8 | .589 |
| Ross Ohlendorf | RYS | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 3 | 2 | .667 | 39.3 | .492 |
| Will Ohman* | NEP | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 | 20.0 | .627 |
| Hideki Okajima* | CBB | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 8 | .800 | 21.0 | .665 |
| Darren Oliver* | BBG | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 22.7 | .626 |
| Scott Olsen* | CIO | sp | 23 | 2 | 0 | .000 | 0 | 0 | .000 | 8 | 4.0 | 5 | 1 | .200 | 28.8 | .607 |
| Ramon Ortiz | FDH | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 8 | .471 | 25.6 | .647 |
| Roy Oswalt | CEN | sp | 29 | 33 | 3 | .091 | 2 | 19 | .576 | 218 | 6.6 | 20 | 9 | .450 | 95.7 | .653 |
| Akinori Otsuka | CEN | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 1 | .071 | 16.4 | .644 |
| Micah Owings | SOI | sp | 24 | 3 | 0 | .000 | 0 | 2 | .667 | 18 | 6.0 | 4 | 0 | .000 | 63.8 | .639 |
| Vicente Padilla | CIN | sp | 29 | 1 | 1 | 1.000 | 0 | 1 | 1.000 | 6 | 6.0 | 0 | 0 | .000 | 109.0 | .587 |
| Jonathan Papelbon | HAR | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 16.1 | .664 |
| Manny Parra* | NYD | mr | 24 | 6 | 0 | .000 | 0 | 1 | .167 | 28 | 4.7 | 7 | 1 | .143 | 89.3 | .576 |
| Troy Patton* | TEW | sp | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 18.9 | .624 |
| Carl Pavano | NEP | sp | 31 | 1 | 0 | .000 | 0 | 1 | 1.000 | 4 | 4.0 | 0 | 0 | .000 | 23.5 | .670 |
| Jake Peavy | SOI | sp | 26 | 33 | 2 | .061 | 2 | 23 | .697 | 237 | 7.2 | 11 | 1 | .091 | 108.5 | .633 |
| Mike Pelfrey | REN | sp | 23 | 9 | 0 | .000 | 0 | 2 | .222 | 44 | 4.9 | 23 | 6 | .261 | 39.2 | .590 |
| Ramon Antonio Pena | GAR | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 | 23.3 | .640 |
| Brad Penny | RMO | sp | 29 | 31 | 2 | .065 | 2 | 14 | .452 | 151 | 4.9 | 16 | 4 | .250 | 97.3 | .607 |
| Joel Peralta | BBG | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 8 | .400 | 20.2 | .675 |
| Troy Percival | BAR | mr | 37 | 1 | 0 | .000 | 0 | 1 | 1.000 | 2 | 2.0 | 4 | 1 | .250 | 18.8 | .664 |
| Odalis Perez* | CIO | sp | 30 | 7 | 0 | .000 | 0 | 1 | .143 | 23 | 3.3 | 6 | 2 | .333 | 48.3 | .618 |
| Oliver Perez* | RMO | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 | 19.0 | .509 |
| Rafael Perez* | SOI | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 26.7 | .656 |
| Glen Perkins* | ATM | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 8 | 8.0 | 3 | 0 | .000 | 28.5 | .616 |
| Yusmeiro Petit | RYS | sp | 22 | 6 | 0 | .000 | 0 | 4 | .667 | 26 | 4.3 | 4 | 1 | .250 | 47.9 | .633 |
| Andy Pettitte* | HAR | sp | 35 | 33 | 1 | .030 | 0 | 15 | .455 | 173 | 5.2 | 21 | 9 | .429 | 83.5 | .640 |
| Joel Pineiro | BRK | mr | 28 | 1 | 0 | .000 | 0 | 0 | .000 | 7 | 7.0 | 35 | 6 | .171 | 19.0 | .631 |
| Scott Proctor | BBG | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 9 | .563 | 16.4 | .581 |
| J.J. Putz | HAR | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 18.2 | .655 |
| Chad Qualls | PHI | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 10 | .500 | 15.5 | .611 |
| Edwar Ramirez | TEW | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 11.3 | .588 |
| Horacio Ramirez* | CIO | sp | 27 | 12 | 0 | .000 | 0 | 0 | .000 | 70 | 5.8 | 36 | 12 | .333 | 37.3 | .578 |
| Ramon Ramirez | PHI | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 | 18.0 | .630 |
| Jon Rauch | CIN | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 | 21.5 | .658 |
| Chris Ray | NYD | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 23.8 | .623 |
| Tim Redding | CEN | sp | 29 | 1 | 0 | .000 | 0 | 1 | 1.000 | 8 | 8.0 | 2 | 0 | .000 | 38.3 | .591 |
| Al Reyes | CBB | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 19.0 | .630 |
| Anthony Reyes | FDH | sp | 25 | 6 | 0 | .000 | 0 | 5 | .833 | 14 | 2.3 | 5 | 2 | .400 | 76.1 | .618 |
| David Riske | CBB | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 | 18.1 | .647 |
| Mariano Rivera | CTW | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 17.1 | .679 |
| Saul Rivera | PHI | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 10 | .294 | 21.3 | .553 |
| Nate Robertson* |   | sp | 29 | 1 | 0 | .000 | 0 | 1 | 1.000 | 3 | 3.0 | 22 | 5 | .227 | 23.3 | .632 |
| Fernando Rodney | BBG | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 23.7 | .596 |
| Francisco Rodriguez |   | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 | 19.8 | .594 |
| Wandy Rodriguez* | ATM | sp | 28 | 26 | 0 | .000 | 0 | 10 | .385 | 99 | 3.8 | 17 | 7 | .412 | 95.6 | .615 |
| Kenny Rogers* | CBB | sp | 42 | 13 | 0 | .000 | 0 | 5 | .385 | 58 | 4.5 | 4 | 2 | .500 | 82.2 | .627 |
| J.C. Romero* | PHI | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 6 | .286 | 17.3 | .556 |
| Ryan Rowland-Smith* | NEP | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 | 25.0 | .616 |
| B.J. Ryan* | CTW | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 48.5 | .567 |
| Kirk Saarloos | REN | mr | 28 | 2 | 0 | .000 | 0 | 0 | .000 | 7 | 3.5 | 12 | 4 | .333 | 24.5 | .587 |
| C.C. Sabathia* | ATM | sp | 26 | 33 | 3 | .091 | 1 | 20 | .606 | 147 | 4.5 | 6 | 1 | .167 | 100.9 | .687 |
| Takashi Saito | GAR | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 18.3 | .638 |
| Chris Sampson | TEW | sp | 29 | 18 | 0 | .000 | 0 | 8 | .444 | 85 | 4.7 | 12 | 3 | .250 | 84.3 | .640 |
| Brian Sanches | BRK | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 19.4 | .571 |
| Anibal Sanchez | CIN | sp | 23 | 7 | 0 | .000 | 0 | 0 | .000 | 32 | 4.6 | 14 | 1 | .071 | 69.3 | .551 |
| Jonathan Sanchez* | RYS | mr | 24 | 7 | 0 | .000 | 0 | 2 | .286 | 37 | 5.3 | 7 | 2 | .286 | 46.1 | .580 |
| Ervin Santana | ATM | sp | 24 | 24 | 0 | .000 | 0 | 8 | .333 | 140 | 5.8 | 14 | 6 | .429 | 78.7 | .624 |
| Johan Santana* | GAR | sp | 28 | 33 | 0 | .000 | 0 | 18 | .545 | 194 | 5.9 | 12 | 5 | .417 | 94.2 | .666 |
| Dennis Sarfate | GAR | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 19.5 | .590 |
| Joe Saunders* | RMO | sp | 26 | 3 | 0 | .000 | 0 | 3 | 1.000 | 15 | 5.0 | 0 | 0 | .000 | 77.5 | .648 |
| Curt Schilling | CEN | sp | 40 | 26 | 3 | .115 | 2 | 15 | .577 | 129 | 5.0 | 10 | 5 | .500 | 88.0 | .690 |
| Chris Schroder | TEW | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 3 | .176 | 23.0 | .629 |
| Bobby Seay* | RYS | mr | 29 | 4 | 0 | .000 | 0 | 0 | .000 | 25 | 6.3 | 6 | 3 | .500 | 24.7 | .632 |
| Ben Sheets | TEW | sp | 28 | 24 | 3 | .125 | 1 | 12 | .500 | 130 | 5.4 | 10 | 6 | .600 | 96.1 | .650 |
| George Sherrill* | SOI | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 5 | .417 | 15.4 | .604 |
| James Shields | ATM | sp | 25 | 24 | 0 | .000 | 0 | 13 | .542 | 127 | 5.3 | 19 | 4 | .211 | 100.4 | .663 |
| Scot Shields | HAR | mr | 31 | 1 | 0 | .000 | 0 | 0 | .000 | 9 | 9.0 | 21 | 3 | .143 | 23.5 | .622 |
| Brian Shouse* | BRK | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 6 | .375 | 17.7 | .611 |
| Carlos Silva | TEW | sp | 28 | 12 | 0 | .000 | 0 | 8 | .667 | 66 | 5.5 | 9 | 4 | .444 | 96.7 | .691 |
| Jason Simontacchi | CTW | sp | 33 | 8 | 0 | .000 | 0 | 6 | .750 | 35 | 4.4 | 11 | 7 | .636 | 49.8 | .639 |
| Kevin Slowey | REN | sp | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 9 | .500 | 21.4 | .679 |
| Joe Smith | CTW | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 8 | .800 | 22.9 | .590 |
| John Smoltz | BAR | sp | 40 | 33 | 0 | .000 | 0 | 25 | .758 | 196 | 5.9 | 14 | 4 | .286 | 89.4 | .673 |
| Ian Snell | RMO | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 4 | 1.000 | 26.0 | .608 |
| Kyle Snyder | NYD | mr | 29 | 3 | 0 | .000 | 0 | 0 | .000 | 19 | 6.3 | 4 | 1 | .250 | 29.5 | .546 |
| Andy Sonnanstine | NEP | sp | 24 | 18 | 1 | .056 | 0 | 9 | .500 | 55 | 3.1 | 13 | 3 | .231 | 59.1 | .659 |
| Joakim Soria |   | cl | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 18.0 | .655 |
| Rafael Soriano | GAR | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 2 | .167 | 18.8 | .669 |
| Jorge Sosa | NYD | mr | 30 | 12 | 0 | .000 | 0 | 7 | .583 | 60 | 5.0 | 10 | 5 | .500 | 66.5 | .599 |
| Justin Speier | RMO | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 3 | .231 | 16.9 | .661 |
| Russ Springer | HAR | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 18.1 | .651 |
| Tim Stauffer | REN | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 5 | 1.000 | 24.0 | .560 |
| Mitch Stetter* | RYS | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 16.0 | .542 |
| Huston Street |   | cl | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 | 21.1 | .643 |
| Eric Stults* | REN | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 21.9 | .617 |
| Jeff Suppan | BBG | sp | 32 | 29 | 0 | .000 | 0 | 13 | .448 | 117 | 4.0 | 11 | 5 | .455 | 90.1 | .618 |
| Brian Tallet* | BAR | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 0 | .000 | 20.2 | .629 |
| Taylor Tankersley* | HAR | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 20.0 | .559 |
| Julian Tavarez | CTW | sp | 34 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 21 | 5 | .238 | 24.9 | .627 |
| Robinson Tejeda | FDH | sp | 25 | 17 | 0 | .000 | 0 | 4 | .235 | 69 | 4.1 | 15 | 6 | .400 | 102.3 | .586 |
| Joe Thatcher* | BBG | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 20.1 | .635 |
| Brad Thompson | CTW | mr | 25 | 13 | 0 | .000 | 0 | 1 | .077 | 30 | 2.3 | 12 | 5 | .417 | 56.7 | .598 |
| Matt Thornton* | CIO | mr | 30 | 1 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 1 | .071 | 20.8 | .604 |
| Mike Timlin | CEN | mr | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 | 15.5 | .671 |
| Brett Tomko | RYS | mr | 34 | 9 | 0 | .000 | 0 | 2 | .222 | 49 | 5.4 | 10 | 5 | .500 | 50.9 | .598 |
| Salomon Torres | PHI | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 15.9 | .694 |
| Josh Towers | CIO | sp | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 32.8 | .641 |
| Steve Trachsel | FDH | sp | 36 | 10 | 0 | .000 | 0 | 4 | .400 | 38 | 3.8 | 5 | 2 | .400 | 92.5 | .587 |
| Derrick Turnbow | CIN | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 1 | .071 | 22.8 | .568 |
| Jose Valverde | SOI | cl | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 7 | 7.0 | 17 | 6 | .353 | 20.8 | .615 |
| John Van Benschoten | CIO | sp | 27 | 2 | 0 | .000 | 0 | 0 | .000 | 2 | 1.0 | 29 | 7 | .241 | 29.5 | .530 |
| Rick VandenHurk | CTW | sp | 22 | 9 | 0 | .000 | 0 | 3 | .333 | 52 | 5.8 | 32 | 15 | .469 | 41.5 | .570 |
| Claudio Vargas | BRK | sp | 29 | 11 | 0 | .000 | 0 | 5 | .455 | 45 | 4.1 | 34 | 14 | .412 | 33.6 | .587 |
| Jason Vargas* | REN | sp | 24 | 3 | 0 | .000 | 0 | 0 | .000 | 5 | 1.7 | 3 | 0 | .000 | 64.3 | .689 |
| Javier Vazquez | SOI | sp | 30 | 32 | 2 | .063 | 0 | 18 | .563 | 223 | 7.0 | 7 | 3 | .429 | 96.8 | .657 |
| Jose Veras | RYS | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 23.0 | .609 |
| Justin Verlander | CTW | sp | 24 | 23 | 1 | .043 | 1 | 13 | .565 | 66 | 2.9 | 24 | 10 | .417 | 77.7 | .632 |
| Carlos Villanueva | CIN | mr | 23 | 17 | 1 | .059 | 1 | 9 | .529 | 66 | 3.9 | 17 | 6 | .353 | 63.2 | .588 |
| Oscar Villarreal | HAR | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 22.6 | .626 |
| Ron Villone* | CIN | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 | 21.4 | .613 |
| Luis Vizcaino | PHI | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 | 16.0 | .632 |
| Edinson Volquez | BAR | sp | 23 | 5 | 0 | .000 | 0 | 2 | .400 | 24 | 4.8 | 1 | 0 | .000 | 100.4 | .622 |
| Billy Wagner* | CIN | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 6 | .600 | 24.1 | .595 |
| Adam Wainwright | BRK | sp | 25 | 26 | 0 | .000 | 0 | 15 | .577 | 133 | 5.1 | 12 | 3 | .250 | 103.6 | .622 |
| Tim Wakefield | CIN | sp | 40 | 32 | 0 | .000 | 0 | 21 | .656 | 153 | 4.8 | 20 | 6 | .300 | 88.3 | .622 |
| Jamie Walker* | CBB | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 9 | .321 | 18.5 | .623 |
| Tyler Walker | REN | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 15.0 | .600 |
| Chien-Ming Wang | RMO | sp | 27 | 32 | 2 | .063 | 2 | 19 | .594 | 171 | 5.3 | 14 | 4 | .286 | 93.6 | .627 |
| Jarrod Washburn* | NEP | sp | 32 | 31 | 3 | .097 | 1 | 17 | .548 | 127 | 4.1 | 11 | 5 | .455 | 101.4 | .635 |
| David Weathers | CEN | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 8 | .800 | 20.5 | .603 |
| Jeff Weaver | NEP | sp | 30 | 7 | 0 | .000 | 0 | 6 | .857 | 31 | 4.4 | 1 | 0 | .000 | 95.4 | .672 |
| Jered Weaver | BBG | sp | 24 | 25 | 0 | .000 | 0 | 11 | .440 | 103 | 4.1 | 7 | 1 | .143 | 93.0 | .641 |
| Brandon Webb | BAR | sp | 28 | 32 | 4 | .125 | 2 | 23 | .719 | 204 | 6.4 | 17 | 3 | .176 | 102.9 | .643 |
| Todd Wellemeyer | TEW | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 5 | .556 | 22.1 | .584 |
| David Wells* | CTW | sp | 44 | 19 | 0 | .000 | 0 | 2 | .105 | 77 | 4.1 | 24 | 11 | .458 | 81.2 | .615 |
| Kip Wells |   | sp | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 18.2 | .610 |
| Jake Westbrook | ATM | sp | 29 | 19 | 1 | .053 | 0 | 12 | .632 | 95 | 5.0 | 10 | 2 | .200 | 96.3 | .621 |
| Dan Wheeler | NEP | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 0 | .000 | 20.3 | .667 |
| Sean White | BRK | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 21.2 | .526 |
| Woody Williams | TEW | sp | 40 | 8 | 0 | .000 | 0 | 4 | .500 | 28 | 3.5 | 4 | 0 | .000 | 101.6 | .627 |
| Dontrelle Willis* | REN | sp | 25 | 29 | 2 | .069 | 0 | 12 | .414 | 113 | 3.9 | 21 | 6 | .286 | 101.6 | .609 |
| Brian Wilson | ATM | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 19.8 | .619 |
| C.J. Wilson* | BBG | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 6 | .273 | 19.6 | .581 |
| Matt Wise | CIN | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 19.5 | .692 |
| Randy Wolf* | BRK | sp | 30 | 15 | 0 | .000 | 0 | 7 | .467 | 55 | 3.7 | 14 | 9 | .643 | 93.7 | .607 |
| Kerry Wood | RYS | mr | 30 | 5 | 0 | .000 | 0 | 0 | .000 | 24 | 4.8 | 1 | 0 | .000 | 59.2 | .552 |
| Jamey Wright | FDH | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 8 | .320 | 22.5 | .598 |
| Michael Wuertz | NEP | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 7 | .412 | 20.5 | .604 |
| Chris Young | REN | sp | 28 | 24 | 1 | .042 | 1 | 10 | .417 | 113 | 4.7 | 29 | 12 | .414 | 70.4 | .611 |
| Carlos Zambrano | CEN | sp | 26 | 32 | 2 | .063 | 1 | 21 | .656 | 205 | 6.4 | 19 | 6 | .316 | 103.0 | .608 |
| Barry Zito* | RYS | sp | 29 | 28 | 1 | .036 | 0 | 11 | .393 | 132 | 4.7 | 25 | 11 | .440 | 74.3 | .605 |
| Joel Zumaya | CBB | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 20.1 | .647 |
| Relief |
| Name | Team | P | Age | SVO | S | SV% | BS | BS% | HLD | IR | IRS | IR% | G | GR | GF | PCH/G | STR% |
| David Aardsma | CIO | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 1 | 18 | 6 | .333 | 25 | 25 | 5 | 25.2 | .586 |
| Jeremy Accardo | GAR | cl | 25 | 4 | 3 | .750 | 1 | .250 | 19 | 19 | 5 | .263 | 57 | 57 | 12 | 19.1 | .622 |
| Manny Acosta | BAR | mr | 26 | 1 | 1 | 1.000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 | 24.5 | .592 |
| Jeremy Affeldt* | RYS | mr | 28 | 5 | 1 | .200 | 3 | .600 | 3 | 21 | 6 | .286 | 38 | 38 | 15 | 23.9 | .578 |
| Jonathan Albaladejo | GAR | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 7 | 4 | .571 | 9 | 9 | 4 | 20.6 | .676 |
| Matt Albers | RYS | sp | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 14 | 3 | .214 | 28 | 13 | 2 | 63.1 | .604 |
| Tony Armas | FDH | mr | 29 | 2 | 2 | 1.000 | 0 | .000 | 1 | 5 | 4 | .800 | 24 | 18 | 6 | 35.9 | .648 |
| Bronson Arroyo | PHI | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 36 | 3 | 2 | 88.3 | .633 |
| Scott Atchison | ATM | mr | 31 | 8 | 7 | .875 | 1 | .125 | 0 | 10 | 1 | .100 | 22 | 22 | 16 | 20.2 | .635 |
| Luis Ayala | RMO | mr | 29 | 2 | 0 | .000 | 2 | 1.000 | 5 | 22 | 6 | .273 | 28 | 28 | 9 | 20.3 | .629 |
| Brandon Backe | BAR | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 1 | 1 | 1 | 29.0 | .586 |
| Mike Bacsik* | BRK | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 7 | 2 | 0 | 53.1 | .651 |
| Cha Seung Baek | HAR | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 86.9 | .678 |
| Danys Baez | CTW | mr | 29 | 6 | 3 | .500 | 1 | .167 | 1 | 29 | 12 | .414 | 36 | 36 | 18 | 19.1 | .592 |
| Homer Bailey | FDH | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 100.0 | .567 |
| Scott Baker | BRK | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 21 | 4 | 4 | 85.6 | .640 |
| John Bale* | CEN | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 0 | 19.5 | .692 |
| Grant Balfour | BBG | mr | 29 | 5 | 3 | .600 | 1 | .200 | 4 | 10 | 3 | .300 | 32 | 32 | 6 | 15.6 | .588 |
| Brian Bannister | NEP | sp | 26 | 2 | 0 | .000 | 1 | .500 | 1 | 7 | 3 | .429 | 41 | 20 | 5 | 58.2 | .650 |
| Miguel Batista | PHI | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 0 | .000 | 24 | 7 | 2 | 76.1 | .607 |
| Yorman Bazardo | NYD | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 92.3 | .642 |
| Josh Beckett | SOI | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 96.9 | .694 |
| Erik Bedard* | BAR | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 104.7 | .643 |
| Joe Beimel* | SOI | mr | 30 | 2 | 2 | 1.000 | 0 | .000 | 4 | 9 | 2 | .222 | 12 | 12 | 6 | 8.1 | .608 |
| Matt Belisle | FDH | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 33 | 6 | 2 | 73.1 | .644 |
| Heath Bell | NYD | mr | 29 | 12 | 10 | .833 | 2 | .167 | 3 | 25 | 5 | .200 | 52 | 52 | 26 | 24.7 | .604 |
| Jeff Bennett | REN | sp | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 1 | .200 | 11 | 11 | 6 | 20.7 | .570 |
| Joaquin Benoit | NEP | mr | 29 | 29 | 23 | .793 | 6 | .207 | 3 | 30 | 4 | .133 | 57 | 57 | 46 | 20.6 | .633 |
| Jason Bergmann | RYS | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 11 | 1 | 1 | 78.1 | .590 |
| Rafael Betancourt | BAR | mr | 32 | 32 | 30 | .938 | 2 | .063 | 1 | 27 | 3 | .111 | 61 | 61 | 48 | 16.9 | .721 |
| Chad Billingsley | RMO | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 36 | 14 | 6 | 69.7 | .595 |
| Nick Blackburn | REN | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 1 | .200 | 7 | 7 | 2 | 27.9 | .728 |
| Joe Blanton | HAR | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 91.6 | .676 |
| Jerry Blevins* | CTW | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 4 | 4 | 0 | 16.3 | .615 |
| Jeremy Bonderman | HAR | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 79.6 | .644 |
| Boof Bonser | CBB | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 1 | 1 | 81.9 | .594 |
| Joe Borowski | PHI | cl | 36 | 4 | 3 | .750 | 1 | .250 | 1 | 5 | 2 | .400 | 16 | 16 | 8 | 18.6 | .653 |
| Blaine Boyer | CBB | mr | 25 | 2 | 0 | .000 | 2 | 1.000 | 0 | 7 | 4 | .571 | 6 | 6 | 0 | 19.3 | .578 |
| Dallas Braden* | RYS | sp | 23 | 2 | 0 | .000 | 2 | 1.000 | 1 | 12 | 4 | .333 | 24 | 16 | 4 | 52.7 | .596 |
| Chad Bradford | CEN | mr | 32 | 2 | 1 | .500 | 1 | .500 | 4 | 20 | 11 | .550 | 30 | 30 | 7 | 22.4 | .666 |
| Bill Bray* | FDH | mr | 24 | 4 | 3 | .750 | 1 | .250 | 0 | 8 | 3 | .375 | 11 | 11 | 9 | 18.5 | .662 |
| Chris Britton | BAR | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 5 | 5 | 2 | 14.8 | .676 |
| Lance Broadway | NYD | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 101.5 | .616 |
| Doug Brocail | TEW | mr | 40 | 8 | 5 | .625 | 2 | .250 | 1 | 16 | 3 | .188 | 37 | 37 | 17 | 19.2 | .621 |
| Andrew Brown | HAR | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 6 | 0 | .000 | 14 | 14 | 5 | 28.1 | .609 |
| Jonathan Broxton | NYD | mr | 23 | 10 | 7 | .700 | 3 | .300 | 9 | 27 | 9 | .333 | 58 | 58 | 18 | 23.7 | .634 |
| Brian Bruney | BRK | mr | 25 | 3 | 1 | .333 | 1 | .333 | 1 | 29 | 9 | .310 | 45 | 45 | 14 | 21.8 | .526 |
| Clay Buchholz | RYS | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 1 | 1 | 85.3 | .566 |
| Taylor Buchholz | TEW | mr | 25 | 4 | 2 | .500 | 2 | .500 | 8 | 49 | 13 | .265 | 64 | 64 | 23 | 22.2 | .650 |
| Mark Buehrle* | RMO | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 91.8 | .654 |
| Jason Bulger | NEP | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 2 | 2 | 0 | 54.5 | .606 |
| A.J. Burnett | CIN | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 36 | 9 | 2 | 78.9 | .614 |
| Brian Burres* | BRK | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 11 | 5 | 2 | 62.8 | .606 |
| Jared Burton | SOI | mr | 26 | 2 | 2 | 1.000 | 0 | .000 | 3 | 8 | 3 | .375 | 8 | 8 | 2 | 15.4 | .610 |
| Dave Bush | NEP | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 92.8 | .645 |
| Paul Byrd | NEP | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 83.6 | .696 |
| Tim Byrdak* | CIN | mr | 33 | 7 | 3 | .429 | 4 | .571 | 3 | 15 | 6 | .400 | 34 | 34 | 10 | 24.4 | .601 |
| Daniel Cabrera | BBG | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 0 | .000 | 30 | 6 | 0 | 80.6 | .597 |
| Matt Cain | CEN | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 93.8 | .597 |
| Kiko Calero | CIO | mr | 32 | 3 | 1 | .333 | 2 | .667 | 1 | 24 | 5 | .208 | 30 | 30 | 9 | 20.9 | .620 |
| Kevin Cameron | REN | mr | 27 | 6 | 1 | .167 | 4 | .667 | 5 | 17 | 8 | .471 | 33 | 33 | 13 | 23.5 | .611 |
| Shawn Camp | ATM | mr | 31 | 7 | 3 | .429 | 3 | .429 | 3 | 18 | 8 | .444 | 41 | 41 | 12 | 17.7 | .603 |
| Jorge Campillo | NEP | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 49.3 | .579 |
| Matt Capps | NYD | mr | 23 | 14 | 12 | .857 | 2 | .143 | 2 | 40 | 11 | .275 | 55 | 55 | 29 | 20.0 | .688 |
| Buddy Carlyle | REN | sp | 29 | 3 | 2 | .667 | 1 | .333 | 2 | 46 | 11 | .239 | 61 | 58 | 20 | 23.6 | .630 |
| Fausto Carmona | RMO | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 91.9 | .638 |
| Chris Carpenter | CIO | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 110.0 | .564 |
| Santiago Casilla | BBG | mr | 26 | 2 | 1 | .500 | 1 | .500 | 5 | 28 | 11 | .393 | 47 | 47 | 7 | 19.6 | .612 |
| Shawn Chacon | RMO | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 1 | 1 | 1 | 4.0 | .750 |
| Joba Chamberlain | BAR | mr | 21 | 5 | 5 | 1.000 | 0 | .000 | 2 | 7 | 1 | .143 | 19 | 19 | 8 | 21.3 | .634 |
| Bruce Chen* | REN | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 3 | 1.000 | 9 | 9 | 6 | 23.4 | .583 |
| Matt Chico* | CTW | sp | 24 | 1 | 0 | .000 | 1 | 1.000 | 0 | 4 | 2 | .500 | 29 | 11 | 4 | 71.3 | .591 |
| Randy Choate* | RYS | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 | 25.0 | .560 |
| Roger Clemens | HAR | sp | 44 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 96.6 | .623 |
| Tyler Clippard | BRK | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 74.1 | .557 |
| Todd Coffey | RYS | mr | 26 | 4 | 1 | .250 | 2 | .500 | 1 | 19 | 9 | .474 | 30 | 30 | 8 | 23.3 | .615 |
| Jesus Colome | CIN | mr | 29 | 2 | 2 | 1.000 | 0 | .000 | 0 | 6 | 2 | .333 | 7 | 7 | 4 | 29.1 | .623 |
| Bartolo Colon | REN | sp | 34 | 5 | 1 | .200 | 4 | .800 | 4 | 48 | 16 | .333 | 66 | 63 | 15 | 24.3 | .653 |
| Clay Condrey | ATM | mr | 31 | 3 | 0 | .000 | 3 | 1.000 | 3 | 27 | 15 | .556 | 33 | 33 | 8 | 19.8 | .619 |
| Jose Contreras | NEP | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 1 | 1 | 92.6 | .634 |
| Aaron Cook | CIN | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 0 | .000 | 27 | 6 | 1 | 75.0 | .641 |
| Chad Cordero | SOI | cl | 25 | 5 | 3 | .600 | 1 | .200 | 8 | 23 | 8 | .348 | 57 | 57 | 22 | 20.7 | .628 |
| Francisco Cordero | CIN | cl | 32 | 12 | 8 | .667 | 3 | .250 | 2 | 17 | 4 | .235 | 39 | 39 | 15 | 25.9 | .634 |
| Lance Cormier | REN | sp | 26 | 3 | 2 | .667 | 1 | .333 | 1 | 9 | 2 | .222 | 18 | 14 | 5 | 42.9 | .620 |
| Manny Corpas | RMO | mr | 24 | 37 | 35 | .946 | 2 | .054 | 3 | 30 | 10 | .333 | 74 | 74 | 58 | 16.1 | .662 |
| Kevin Correia | ATM | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 98.3 | .651 |
| Neal Cotts* | FDH | mr | 27 | 8 | 6 | .750 | 2 | .250 | 1 | 10 | 1 | .100 | 19 | 19 | 11 | 16.7 | .575 |
| Jesse Crain | TEW | mr | 25 | 3 | 2 | .667 | 1 | .333 | 0 | 8 | 2 | .250 | 11 | 11 | 9 | 18.2 | .655 |
| Juan Cruz | HAR | mr | 28 | 10 | 4 | .400 | 6 | .600 | 10 | 17 | 6 | .353 | 50 | 50 | 15 | 20.5 | .618 |
| John Danks* | BRK | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 22 | 1 | 0 | 92.6 | .620 |
| Kyle Davies | CIO | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 1 | .250 | 26 | 10 | 2 | 50.0 | .570 |
| Doug Davis* | RYS | sp | 31 | 1 | 1 | 1.000 | 0 | .000 | 1 | 7 | 4 | .571 | 44 | 21 | 9 | 63.7 | .592 |
| Jorge De La Rosa* | CIO | sp | 26 | 5 | 2 | .400 | 2 | .400 | 9 | 70 | 16 | .229 | 92 | 84 | 13 | 24.4 | .606 |
| Manny Delcarmen | HAR | mr | 25 | 3 | 2 | .667 | 0 | .000 | 5 | 13 | 0 | .000 | 33 | 33 | 14 | 21.2 | .619 |
| Ryan Dempster | BAR | cl | 30 | 2 | 1 | .500 | 1 | .500 | 2 | 18 | 8 | .444 | 37 | 31 | 13 | 25.9 | .581 |
| Ross Detwiler* | HAR | mr | 21 | 1 | 1 | 1.000 | 0 | .000 | 0 | 2 | 0 | .000 | 2 | 2 | 2 | 17.0 | .647 |
| Joey Devine | ATM | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 2 | .333 | 7 | 7 | 5 | 21.0 | .565 |
| Lenny DiNardo* | RYS | sp | 27 | 3 | 3 | 1.000 | 0 | .000 | 2 | 9 | 2 | .222 | 36 | 21 | 8 | 56.3 | .587 |
| Brendan Donnelly | GAR | mr | 35 | 2 | 2 | 1.000 | 0 | .000 | 2 | 10 | 1 | .100 | 14 | 14 | 5 | 16.6 | .694 |
| Octavio Dotel | FDH | cl | 33 | 14 | 9 | .643 | 5 | .357 | 1 | 18 | 5 | .278 | 32 | 32 | 21 | 17.1 | .613 |
| Scott Downs* | SOI | mr | 31 | 17 | 8 | .471 | 5 | .294 | 10 | 23 | 6 | .261 | 60 | 60 | 25 | 15.8 | .609 |
| Justin Duchscherer | BAR | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 12 | 10 | 6 | 19.8 | .620 |
| Zach Duke* | CTW | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 21 | 1 | 1 | 85.2 | .617 |
| Chad Durbin | RYS | sp | 29 | 1 | 0 | .000 | 1 | 1.000 | 1 | 0 | 0 | .000 | 25 | 8 | 1 | 72.6 | .601 |
| J.D. Durbin | BRK | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 10 | 1 | 1 | 86.7 | .580 |
| Adam Eaton | CIO | sp | 29 | 1 | 0 | .000 | 1 | 1.000 | 2 | 15 | 3 | .200 | 42 | 22 | 6 | 48.0 | .562 |
| Scott Elarton | CIO | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 2 | .500 | 17 | 11 | 7 | 40.5 | .557 |
| Alan Embree* | CBB | cl | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 | 13.0 | .769 |
| Kelvim Escobar | GAR | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 1 | 1 | 99.2 | .615 |
| Scott Feldman | BBG | mr | 24 | 5 | 2 | .400 | 2 | .400 | 6 | 14 | 5 | .357 | 36 | 36 | 5 | 21.3 | .542 |
| Pedro Feliciano* | SOI | mr | 30 | 3 | 1 | .333 | 0 | .000 | 2 | 16 | 3 | .188 | 21 | 21 | 7 | 18.7 | .585 |
| Gavin Floyd | CIN | sp | 24 | 2 | 0 | .000 | 2 | 1.000 | 0 | 19 | 8 | .421 | 26 | 20 | 5 | 41.0 | .640 |
| Josh Fogg | BBG | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 21 | 4 | 0 | 69.5 | .611 |
| Casey Fossum* | CTW | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 1 | 2 | 1 | .500 | 21 | 7 | 0 | 69.4 | .623 |
| Jeff Francis* | GAR | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 93.7 | .637 |
| Frank Francisco | NEP | mr | 27 | 5 | 2 | .400 | 1 | .200 | 1 | 27 | 8 | .296 | 49 | 49 | 11 | 21.6 | .565 |
| Ryan Franklin | CBB | mr | 34 | 4 | 3 | .750 | 1 | .250 | 2 | 30 | 9 | .300 | 57 | 57 | 25 | 20.1 | .679 |
| Jason Frasor | RYS | mr | 29 | 11 | 6 | .545 | 4 | .364 | 5 | 41 | 21 | .512 | 53 | 53 | 31 | 17.4 | .596 |
| Brian Fuentes* | HAR | cl | 31 | 11 | 7 | .636 | 4 | .364 | 15 | 28 | 9 | .321 | 57 | 57 | 16 | 18.6 | .594 |
| Aaron Fultz* | PHI | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 11 | 5 | .455 | 12 | 12 | 9 | 21.3 | .580 |
| Kason Gabbard* | NYD | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 98.0 | .565 |
| Eric Gagne | CEN | cl | 31 | 0 | 0 | .000 | 0 | .000 | 1 | 11 | 3 | .273 | 18 | 18 | 6 | 23.3 | .618 |
| Armando Galarraga | NEP | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 93.5 | .561 |
| Yovani Gallardo | PHI | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 104.9 | .622 |
| Freddy Garcia | CTW | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 99.2 | .619 |
| Lee Gardner | PHI | mr | 32 | 9 | 5 | .556 | 3 | .333 | 9 | 33 | 12 | .364 | 58 | 58 | 17 | 16.8 | .630 |
| Jon Garland | BAR | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 4 | 2 | 82.2 | .657 |
| Matt Garza | TEW | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 102.3 | .580 |
| Chad Gaudin | ATM | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 1 | .250 | 13 | 5 | 1 | 64.1 | .628 |
| Geoff Geary | NEP | mr | 30 | 2 | 0 | .000 | 2 | 1.000 | 5 | 19 | 8 | .421 | 50 | 50 | 14 | 20.1 | .615 |
| Justin Germano | TEW | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 86.4 | .616 |
| Dan Giese | CBB | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 6 | 6 | 5 | 30.7 | .636 |
| Tom Glavine* | BBG | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 37 | 6 | 1 | 73.5 | .612 |
| Mike Gonzalez* | BAR | mr | 29 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 0 | .000 | 5 | 5 | 1 | 19.8 | .495 |
| Tom Gordon | REN | mr | 39 | 15 | 12 | .800 | 3 | .200 | 2 | 16 | 4 | .250 | 35 | 35 | 27 | 19.7 | .624 |
| Tom Gorzelanny* | GAR | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 96.6 | .611 |
| John Grabow* | RYS | mr | 28 | 4 | 3 | .750 | 1 | .250 | 5 | 10 | 2 | .200 | 29 | 29 | 13 | 25.2 | .631 |
| Sean Green | ATM | mr | 28 | 3 | 1 | .333 | 2 | .667 | 0 | 14 | 6 | .429 | 21 | 21 | 14 | 19.8 | .589 |
| Kevin Gregg | RYS | cl | 29 | 0 | 0 | .000 | 0 | .000 | 7 | 29 | 6 | .207 | 45 | 39 | 6 | 25.2 | .568 |
| Zack Greinke | ATM | mr | 23 | 2 | 1 | .500 | 1 | .500 | 1 | 12 | 1 | .083 | 31 | 14 | 9 | 61.0 | .638 |
| Jason Grilli | ATM | mr | 30 | 9 | 4 | .444 | 4 | .444 | 2 | 26 | 9 | .346 | 49 | 49 | 19 | 22.8 | .618 |
| Eddie Guardado* | CTW | mr | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 13 | 8 | .615 | 8 | 8 | 1 | 22.8 | .676 |
| Matt Guerrier | BAR | mr | 28 | 7 | 2 | .286 | 4 | .571 | 20 | 32 | 13 | .406 | 75 | 75 | 24 | 17.6 | .651 |
| Jeremy Guthrie | BAR | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 86.8 | .657 |
| Angel Guzman | CIO | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 0 | .000 | 10 | 9 | 4 | 38.9 | .584 |
| Roy Halladay | PHI | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 34 | 1 | 1 | 98.4 | .665 |
| Cole Hamels* | FDH | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 1 | 0 | 94.3 | .652 |
| Jason Hammel | REN | sp | 24 | 1 | 0 | .000 | 1 | 1.000 | 2 | 9 | 8 | .889 | 30 | 17 | 9 | 51.6 | .605 |
| Justin Hampson* | BAR | mr | 27 | 5 | 0 | .000 | 2 | .400 | 9 | 15 | 3 | .200 | 44 | 44 | 7 | 17.1 | .628 |
| Joel Hanrahan | BBG | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 4 | 1.000 | 16 | 6 | 2 | 60.6 | .559 |
| J.A. Happ* | RYS | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 2 | 1 | 0 | 50.0 | .590 |
| Aaron Harang | CBB | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 106.4 | .660 |
| Rich Harden | BRK | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 6 | 3 | 2 | 62.5 | .600 |
| Dan Haren | CIO | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 0 | 7 | 0 | .000 | 42 | 8 | 4 | 64.1 | .664 |
| LaTroy Hawkins | RMO | mr | 34 | 3 | 1 | .333 | 2 | .667 | 3 | 21 | 9 | .429 | 40 | 40 | 11 | 19.6 | .624 |
| Aaron Heilman | GAR | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 2 | .500 | 10 | 10 | 6 | 23.2 | .634 |
| Mark Hendrickson* | NYD | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 75.0 | .652 |
| Brad Hennessey | CIN | cl | 27 | 1 | 1 | 1.000 | 0 | .000 | 1 | 5 | 2 | .400 | 10 | 10 | 4 | 19.5 | .621 |
| Clay Hensley | TEW | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 88.2 | .577 |
| Matt Herges | CBB | mr | 37 | 24 | 23 | .958 | 1 | .042 | 0 | 18 | 7 | .389 | 43 | 43 | 36 | 16.3 | .623 |
| Felix Hernandez | CBB | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 95.5 | .635 |
| Livan Hernandez | FDH | sp | 32 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 15 | 3 | 0 | 73.5 | .605 |
| Orlando Hernandez | NYD | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 91.4 | .604 |
| Rich Hill* | SOI | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 98.1 | .613 |
| Shawn Hill | RMO | sp | 26 | 6 | 3 | .500 | 2 | .333 | 10 | 24 | 3 | .125 | 52 | 50 | 16 | 21.3 | .622 |
| Jason Hirsh | HAR | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 81.6 | .612 |
| Luke Hochevar | HAR | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 97.5 | .621 |
| Trevor Hoffman | GAR | cl | 39 | 13 | 10 | .769 | 3 | .231 | 7 | 19 | 7 | .368 | 48 | 48 | 29 | 18.2 | .670 |
| J.P. Howell* | CIO | sp | 24 | 12 | 5 | .417 | 7 | .583 | 1 | 16 | 8 | .500 | 35 | 32 | 20 | 26.1 | .622 |
| Bob Howry | GAR | mr | 33 | 2 | 1 | .500 | 1 | .500 | 2 | 5 | 2 | .400 | 13 | 13 | 6 | 20.5 | .632 |
| Tim Hudson | SOI | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 90.6 | .637 |
| Phil Hughes | NYD | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 84.9 | .608 |
| Philip Humber | BBG | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 3 | 2 | 1 | 47.7 | .594 |
| Jason Isringhausen | CEN | cl | 34 | 5 | 2 | .400 | 3 | .600 | 14 | 27 | 5 | .185 | 53 | 53 | 11 | 18.6 | .596 |
| Edwin Jackson | REN | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 1 | 1 | 87.9 | .599 |
| Chuck James* | FDH | sp | 25 | 2 | 1 | .500 | 1 | .500 | 0 | 5 | 1 | .200 | 17 | 12 | 9 | 47.4 | .619 |
| Casey Janssen | TEW | mr | 25 | 6 | 3 | .500 | 3 | .500 | 10 | 28 | 11 | .393 | 60 | 60 | 17 | 18.9 | .630 |
| Bobby Jenks | TEW | cl | 26 | 18 | 16 | .889 | 2 | .111 | 0 | 36 | 8 | .222 | 55 | 55 | 43 | 18.0 | .692 |
| Jason Jennings | BRK | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 90.1 | .600 |
| Ubaldo Jimenez | CIO | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 3 | .500 | 24 | 17 | 7 | 44.8 | .572 |
| Jim Johnson | TEW | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 3 | 1.000 | 1 | 1 | 0 | 28.0 | .500 |
| Josh Johnson | BBG | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 80.7 | .620 |
| Randy Johnson* | GAR | sp | 43 | 1 | 0 | .000 | 1 | 1.000 | 0 | 2 | 1 | .500 | 11 | 3 | 2 | 74.5 | .677 |
| Todd Jones | CTW | cl | 39 | 0 | 0 | .000 | 0 | .000 | 3 | 20 | 10 | .500 | 28 | 28 | 14 | 19.3 | .633 |
| Jair Jurrjens | NEP | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 92.8 | .631 |
| Jeff Karstens | FDH | mr | 24 | 2 | 0 | .000 | 2 | 1.000 | 0 | 5 | 2 | .400 | 13 | 12 | 7 | 25.2 | .582 |
| Scott Kazmir* | HAR | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 100.0 | .607 |
| Kyle Kendrick | CIN | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 3 | .600 | 23 | 3 | 0 | 71.2 | .653 |
| Ian Kennedy | BBG | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 1 | 1 | 77.8 | .601 |
| Byung-Hyun Kim | CTW | sp | 28 | 3 | 1 | .333 | 2 | .667 | 0 | 14 | 6 | .429 | 35 | 29 | 15 | 39.4 | .604 |
| Hong-Chih Kuo* | NYD | sp | 25 | 8 | 6 | .750 | 2 | .250 | 8 | 21 | 5 | .238 | 29 | 28 | 13 | 20.4 | .624 |
| John Lackey | GAR | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 102.6 | .660 |
| Aaron Laffey* | NYD | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 85.1 | .667 |
| John Lannan* | RYS | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 108.8 | .584 |
| Brandon League | ATM | mr | 24 | 1 | 0 | .000 | 0 | .000 | 1 | 4 | 2 | .500 | 8 | 8 | 2 | 24.0 | .552 |
| Cliff Lee* | BRK | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 1 | .200 | 17 | 3 | 3 | 77.8 | .609 |
| Jon Lester* | CIO | sp | 23 | 2 | 1 | .500 | 1 | .500 | 0 | 16 | 6 | .375 | 27 | 24 | 5 | 31.0 | .599 |
| Colby Lewis | BBG | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 11 | 6 | 3 | 60.7 | .626 |
| Jensen Lewis | BAR | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 2 | 26.3 | .595 |
| Brad Lidge | BRK | cl | 30 | 6 | 2 | .333 | 4 | .667 | 6 | 34 | 6 | .176 | 51 | 51 | 15 | 18.7 | .609 |
| Ted Lilly* | CIN | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 33 | 2 | 0 | 79.7 | .645 |
| Tim Lincecum | NYD | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 99.7 | .597 |
| Matt Lindstrom | PHI | mr | 27 | 8 | 7 | .875 | 0 | .000 | 5 | 38 | 7 | .184 | 64 | 64 | 16 | 17.6 | .619 |
| Scott Linebrink | ATM | mr | 30 | 10 | 5 | .500 | 5 | .500 | 1 | 28 | 12 | .429 | 47 | 47 | 26 | 19.0 | .607 |
| Jesse Litsch | REN | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 2 | .286 | 19 | 5 | 1 | 78.8 | .617 |
| Wes Littleton | BAR | mr | 24 | 0 | 0 | .000 | 0 | .000 | 2 | 11 | 5 | .455 | 23 | 23 | 5 | 26.3 | .636 |
| Bobby Livingston* | PHI | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 87.0 | .667 |
| Kameron Loe | FDH | sp | 25 | 2 | 1 | .500 | 1 | .500 | 0 | 5 | 2 | .400 | 30 | 10 | 5 | 66.0 | .610 |
| Kyle Lohse | FDH | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 2 | 2 | 86.1 | .623 |
| Braden Looper | CBB | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 97.1 | .631 |
| Javier Lopez* | RYS | mr | 29 | 8 | 4 | .500 | 2 | .250 | 3 | 26 | 4 | .154 | 37 | 37 | 10 | 14.6 | .586 |
| Rodrigo Lopez | CBB | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 93.1 | .654 |
| Derek Lowe | TEW | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 99.7 | .621 |
| Mark Lowe | HAR | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 50.0 | .640 |
| Brandon Lyon | FDH | mr | 27 | 4 | 3 | .750 | 1 | .250 | 3 | 32 | 14 | .438 | 47 | 47 | 15 | 21.0 | .632 |
| Greg Maddux | CBB | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 82.9 | .702 |
| Ryan Madson | BBG | mr | 26 | 4 | 2 | .500 | 2 | .500 | 4 | 19 | 6 | .316 | 39 | 39 | 6 | 21.8 | .616 |
| Ron Mahay* | NYD | mr | 36 | 14 | 8 | .571 | 5 | .357 | 10 | 16 | 2 | .125 | 45 | 45 | 18 | 24.0 | .545 |
| John Maine | TEW | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 88.6 | .613 |
| Shaun Marcum | PHI | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 27 | 1 | 0 | 85.1 | .633 |
| Carlos Marmol | SOI | mr | 24 | 18 | 13 | .722 | 2 | .111 | 14 | 38 | 12 | .316 | 61 | 61 | 30 | 20.5 | .595 |
| Mike Maroth* | CIO | sp | 29 | 10 | 3 | .300 | 7 | .700 | 6 | 46 | 14 | .304 | 78 | 68 | 14 | 26.9 | .598 |
| Jason Marquis | CIO | sp | 28 | 1 | 1 | 1.000 | 0 | .000 | 1 | 3 | 0 | .000 | 40 | 11 | 4 | 64.8 | .584 |
| Sean Marshall* | BBG | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 2 | .333 | 20 | 6 | 3 | 70.6 | .614 |
| Damaso Marte* | ATM | mr | 32 | 1 | 1 | 1.000 | 0 | .000 | 3 | 7 | 1 | .143 | 27 | 27 | 10 | 21.4 | .611 |
| Pedro Martinez | CEN | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 4 | .444 | 10 | 6 | 1 | 53.7 | .637 |
| Nick Masset | CIO | mr | 25 | 8 | 2 | .250 | 5 | .625 | 2 | 21 | 8 | .381 | 37 | 37 | 11 | 21.6 | .584 |
| Daisuke Matsuzaka | CEN | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 99.5 | .618 |
| Brandon McCarthy | BRK | sp | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 26 | 6 | .231 | 43 | 31 | 12 | 39.7 | .576 |
| Dustin McGowan | NYD | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 95.9 | .634 |
| Gil Meche | RMO | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 89.9 | .622 |
| Luis Mendoza | GAR | sp | 23 | 3 | 2 | .667 | 1 | .333 | 0 | 2 | 0 | .000 | 9 | 9 | 8 | 26.4 | .672 |
| Cla Meredith | CBB | mr | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 18 | 10 | .556 | 40 | 39 | 13 | 19.6 | .619 |
| Jose Mesa |   | mr | 41 | 5 | 3 | .600 | 1 | .200 | 5 | 32 | 11 | .344 | 49 | 49 | 15 | 17.1 | .597 |
| Dan Meyer* | BRK | sp | 25 | 6 | 2 | .333 | 4 | .667 | 0 | 8 | 4 | .500 | 14 | 14 | 7 | 24.1 | .599 |
| Andrew Miller* | BRK | sp | 22 | 25 | 14 | .560 | 11 | .440 | 2 | 18 | 11 | .611 | 42 | 39 | 19 | 30.7 | .564 |
| Justin Miller | CIN | mr | 29 | 6 | 5 | .833 | 1 | .167 | 1 | 21 | 6 | .286 | 34 | 34 | 13 | 26.5 | .652 |
| Trever Miller* | CIN | mr | 34 | 4 | 1 | .250 | 3 | .750 | 4 | 18 | 9 | .500 | 35 | 35 | 19 | 18.3 | .576 |
| Kevin Millwood | CTW | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 11 | 4 | .364 | 35 | 13 | 6 | 72.2 | .628 |
| Sergio Mitre | NYD | sp | 26 | 3 | 3 | 1.000 | 0 | .000 | 3 | 7 | 4 | .571 | 36 | 29 | 19 | 34.0 | .627 |
| Franklin Morales* | GAR | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 93.6 | .592 |
| Brandon Morrow | TEW | mr | 22 | 4 | 1 | .250 | 3 | .750 | 9 | 29 | 10 | .345 | 52 | 52 | 14 | 22.0 | .558 |
| Dustin Moseley | PHI | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 101.7 | .650 |
| Guillermo Mota | BRK | mr | 33 | 7 | 4 | .571 | 2 | .286 | 3 | 28 | 11 | .393 | 55 | 55 | 19 | 18.2 | .591 |
| Jamie Moyer* | REN | sp | 44 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 95.6 | .635 |
| Peter Moylan | RMO | mr | 28 | 8 | 2 | .250 | 3 | .375 | 14 | 26 | 8 | .308 | 64 | 64 | 18 | 18.3 | .634 |
| Edward Mujica | ATM | mr | 23 | 4 | 2 | .500 | 2 | .500 | 0 | 6 | 3 | .500 | 10 | 10 | 9 | 16.3 | .669 |
| Mike Mussina | PHI | sp | 38 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 22 | 1 | 0 | 84.6 | .677 |
| Brett Myers | PHI | cl | 26 | 4 | 1 | .250 | 2 | .500 | 1 | 40 | 19 | .475 | 53 | 53 | 10 | 20.3 | .609 |
| Joe Nathan | CEN | cl | 32 | 16 | 14 | .875 | 2 | .125 | 8 | 22 | 5 | .227 | 58 | 58 | 32 | 17.5 | .664 |
| Pat Neshek | NYD | mr | 26 | 15 | 12 | .800 | 2 | .133 | 1 | 20 | 4 | .200 | 46 | 46 | 26 | 22.7 | .645 |
| Ricky Nolasco | ATM | sp | 24 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 9 | 6 | 1 | 41.4 | .619 |
| Leo Nunez | ATM | mr | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 19 | 2 | .105 | 20 | 20 | 5 | 27.0 | .628 |
| Eric O'Flaherty* | RYS | mr | 22 | 4 | 1 | .250 | 2 | .500 | 4 | 22 | 8 | .364 | 36 | 36 | 7 | 19.8 | .589 |
| Ross Ohlendorf | RYS | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 3 | 2 | 1 | 39.3 | .492 |
| Will Ohman* | NEP | mr | 29 | 3 | 1 | .333 | 2 | .667 | 1 | 19 | 6 | .316 | 32 | 32 | 13 | 20.0 | .627 |
| Hideki Okajima* | CBB | mr | 31 | 10 | 7 | .700 | 1 | .100 | 9 | 19 | 3 | .158 | 54 | 54 | 20 | 21.0 | .665 |
| Darren Oliver* | BBG | mr | 36 | 6 | 5 | .833 | 1 | .167 | 1 | 21 | 4 | .190 | 45 | 45 | 28 | 22.7 | .626 |
| Scott Olsen* | CIO | sp | 23 | 4 | 3 | .750 | 1 | .250 | 0 | 25 | 8 | .320 | 30 | 28 | 22 | 28.8 | .607 |
| Ramon Ortiz | FDH | mr | 34 | 6 | 2 | .333 | 3 | .500 | 3 | 50 | 19 | .380 | 65 | 65 | 29 | 25.6 | .647 |
| Roy Oswalt | CEN | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 1 | 1 | 95.7 | .653 |
| Akinori Otsuka | CEN | mr | 35 | 2 | 0 | .000 | 2 | 1.000 | 8 | 8 | 3 | .375 | 33 | 33 | 9 | 16.4 | .644 |
| Micah Owings | SOI | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 2 | 0 | 63.8 | .639 |
| Vicente Padilla | CIN | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 109.0 | .587 |
| Jonathan Papelbon | HAR | cl | 26 | 31 | 27 | .871 | 4 | .129 | 0 | 22 | 5 | .227 | 58 | 58 | 51 | 16.1 | .664 |
| Manny Parra* | NYD | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 89.3 | .576 |
| Troy Patton* | TEW | sp | 21 | 1 | 0 | .000 | 1 | 1.000 | 2 | 3 | 1 | .333 | 9 | 9 | 2 | 18.9 | .624 |
| Carl Pavano | NEP | sp | 31 | 1 | 1 | 1.000 | 0 | .000 | 0 | 9 | 2 | .222 | 8 | 7 | 5 | 23.5 | .670 |
| Jake Peavy | SOI | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 108.5 | .633 |
| Mike Pelfrey | REN | sp | 23 | 1 | 1 | 1.000 | 0 | .000 | 4 | 5 | 0 | .000 | 33 | 24 | 8 | 39.2 | .590 |
| Ramon Antonio Pena | GAR | mr | 25 | 6 | 5 | .833 | 1 | .167 | 3 | 23 | 9 | .391 | 38 | 38 | 17 | 23.3 | .640 |
| Brad Penny | RMO | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 97.3 | .607 |
| Joel Peralta | BBG | mr | 31 | 13 | 10 | .769 | 3 | .231 | 4 | 40 | 16 | .400 | 68 | 68 | 32 | 20.2 | .675 |
| Troy Percival | BAR | mr | 37 | 5 | 4 | .800 | 1 | .200 | 5 | 18 | 7 | .389 | 31 | 30 | 15 | 18.8 | .664 |
| Odalis Perez* | CIO | sp | 30 | 1 | 0 | .000 | 1 | 1.000 | 1 | 9 | 5 | .556 | 18 | 11 | 2 | 48.3 | .618 |
| Oliver Perez* | RMO | sp | 25 | 2 | 1 | .500 | 1 | .500 | 1 | 0 | 0 | .000 | 3 | 3 | 1 | 19.0 | .509 |
| Rafael Perez* | SOI | mr | 25 | 15 | 12 | .800 | 3 | .200 | 2 | 24 | 7 | .292 | 38 | 38 | 25 | 26.7 | .656 |
| Glen Perkins* | ATM | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 2 | 6 | 1 | .167 | 13 | 12 | 4 | 28.5 | .616 |
| Yusmeiro Petit | RYS | sp | 22 | 0 | 0 | .000 | 0 | .000 | 1 | 7 | 2 | .286 | 20 | 14 | 5 | 47.9 | .633 |
| Andy Pettitte* | HAR | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 1 | 1 | 83.5 | .640 |
| Joel Pineiro | BRK | mr | 28 | 4 | 2 | .500 | 2 | .500 | 8 | 49 | 16 | .327 | 65 | 64 | 10 | 19.0 | .631 |
| Scott Proctor | BBG | mr | 30 | 2 | 1 | .500 | 1 | .500 | 6 | 22 | 7 | .318 | 45 | 45 | 9 | 16.4 | .581 |
| J.J. Putz | HAR | cl | 30 | 9 | 8 | .889 | 1 | .111 | 16 | 24 | 0 | .000 | 57 | 57 | 18 | 18.2 | .655 |
| Chad Qualls | PHI | mr | 28 | 19 | 16 | .842 | 3 | .158 | 7 | 32 | 7 | .219 | 82 | 82 | 46 | 15.5 | .611 |
| Edwar Ramirez | TEW | mr | 26 | 1 | 1 | 1.000 | 0 | .000 | 0 | 2 | 0 | .000 | 3 | 3 | 3 | 11.3 | .588 |
| Horacio Ramirez* | CIO | sp | 27 | 1 | 0 | .000 | 0 | .000 | 1 | 28 | 8 | .286 | 43 | 31 | 4 | 37.3 | .578 |
| Ramon Ramirez | PHI | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 3 | 11 | 4 | .364 | 18 | 18 | 8 | 18.0 | .630 |
| Jon Rauch | CIN | mr | 28 | 14 | 9 | .643 | 5 | .357 | 1 | 33 | 13 | .394 | 51 | 51 | 25 | 21.5 | .658 |
| Chris Ray | NYD | cl | 25 | 1 | 0 | .000 | 1 | 1.000 | 1 | 4 | 1 | .250 | 13 | 13 | 2 | 23.8 | .623 |
| Tim Redding | CEN | sp | 29 | 1 | 1 | 1.000 | 0 | .000 | 0 | 1 | 0 | .000 | 3 | 2 | 2 | 38.3 | .591 |
| Al Reyes | CBB | cl | 37 | 8 | 5 | .625 | 3 | .375 | 5 | 27 | 9 | .333 | 55 | 55 | 26 | 19.0 | .630 |
| Anthony Reyes | FDH | sp | 25 | 1 | 0 | .000 | 1 | 1.000 | 1 | 0 | 0 | .000 | 9 | 3 | 0 | 76.1 | .618 |
| David Riske | CBB | mr | 30 | 3 | 1 | .333 | 1 | .333 | 2 | 13 | 1 | .077 | 28 | 28 | 9 | 18.1 | .647 |
| Mariano Rivera | CTW | cl | 37 | 29 | 26 | .897 | 3 | .103 | 1 | 21 | 5 | .238 | 50 | 50 | 45 | 17.1 | .679 |
| Saul Rivera | PHI | mr | 29 | 2 | 2 | 1.000 | 0 | .000 | 5 | 30 | 14 | .467 | 53 | 53 | 12 | 21.3 | .553 |
| Nate Robertson* |   | sp | 29 | 6 | 2 | .333 | 4 | .667 | 9 | 25 | 10 | .400 | 56 | 55 | 18 | 23.3 | .632 |
| Fernando Rodney | BBG | mr | 30 | 7 | 5 | .714 | 1 | .143 | 1 | 23 | 9 | .391 | 38 | 38 | 29 | 23.7 | .596 |
| Francisco Rodriguez |   | cl | 25 | 17 | 12 | .706 | 5 | .294 | 7 | 28 | 10 | .357 | 61 | 61 | 29 | 19.8 | .594 |
| Wandy Rodriguez* | ATM | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 95.6 | .615 |
| Kenny Rogers* | CBB | sp | 42 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 82.2 | .627 |
| J.C. Romero* | PHI | mr | 31 | 4 | 2 | .500 | 0 | .000 | 7 | 25 | 7 | .280 | 55 | 55 | 13 | 17.3 | .556 |
| Ryan Rowland-Smith* | NEP | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 2 | 17 | 3 | .176 | 21 | 21 | 4 | 25.0 | .616 |
| B.J. Ryan* | CTW | cl | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 2 | 2 | 0 | 48.5 | .567 |
| Kirk Saarloos | REN | mr | 28 | 2 | 1 | .500 | 1 | .500 | 0 | 5 | 2 | .400 | 18 | 16 | 5 | 24.5 | .587 |
| C.C. Sabathia* | ATM | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 100.9 | .687 |
| Takashi Saito | GAR | cl | 37 | 30 | 26 | .867 | 4 | .133 | 2 | 19 | 5 | .263 | 49 | 49 | 41 | 18.3 | .638 |
| Chris Sampson | TEW | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 84.3 | .640 |
| Brian Sanches | BRK | mr | 28 | 2 | 1 | .500 | 1 | .500 | 0 | 9 | 4 | .444 | 17 | 17 | 13 | 19.4 | .571 |
| Anibal Sanchez | CIN | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 69.3 | .551 |
| Jonathan Sanchez* | RYS | mr | 24 | 5 | 2 | .400 | 2 | .400 | 0 | 6 | 2 | .333 | 20 | 13 | 6 | 46.1 | .580 |
| Ervin Santana | ATM | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 3 | 3 | 78.7 | .624 |
| Johan Santana* | GAR | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 1 | 1 | 94.2 | .666 |
| Dennis Sarfate | GAR | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 2 | 2 | 1 | 19.5 | .590 |
| Joe Saunders* | RMO | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 0 | 2 | 0 | .000 | 4 | 1 | 1 | 77.5 | .648 |
| Curt Schilling | CEN | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 88.0 | .690 |
| Chris Schroder | TEW | mr | 28 | 6 | 4 | .667 | 2 | .333 | 5 | 15 | 4 | .267 | 34 | 34 | 10 | 23.0 | .629 |
| Bobby Seay* | RYS | mr | 29 | 3 | 2 | .667 | 1 | .333 | 3 | 14 | 4 | .286 | 25 | 21 | 9 | 24.7 | .632 |
| Ben Sheets | TEW | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 96.1 | .650 |
| George Sherrill* | SOI | mr | 30 | 8 | 5 | .625 | 2 | .250 | 14 | 26 | 12 | .462 | 48 | 48 | 17 | 15.4 | .604 |
| James Shields | ATM | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 100.4 | .663 |
| Scot Shields | HAR | mr | 31 | 4 | 2 | .500 | 1 | .250 | 8 | 36 | 10 | .278 | 53 | 52 | 7 | 23.5 | .622 |
| Brian Shouse* | BRK | mr | 38 | 2 | 0 | .000 | 1 | .500 | 3 | 34 | 13 | .382 | 39 | 39 | 9 | 17.7 | .611 |
| Carlos Silva | TEW | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 96.7 | .691 |
| Jason Simontacchi | CTW | sp | 33 | 1 | 0 | .000 | 1 | 1.000 | 2 | 11 | 5 | .455 | 23 | 15 | 3 | 49.8 | .639 |
| Kevin Slowey | REN | sp | 23 | 3 | 1 | .333 | 2 | .667 | 1 | 48 | 19 | .396 | 48 | 48 | 21 | 21.4 | .679 |
| Joe Smith | CTW | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 5 | 26 | 3 | .115 | 28 | 28 | 7 | 22.9 | .590 |
| John Smoltz | BAR | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 89.4 | .673 |
| Ian Snell | RMO | sp | 25 | 5 | 3 | .600 | 2 | .400 | 2 | 33 | 12 | .364 | 32 | 32 | 14 | 26.0 | .608 |
| Kyle Snyder | NYD | mr | 29 | 1 | 1 | 1.000 | 0 | .000 | 0 | 4 | 0 | .000 | 10 | 7 | 3 | 29.5 | .546 |
| Andy Sonnanstine | NEP | sp | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 10 | 2 | .200 | 34 | 16 | 6 | 59.1 | .659 |
| Joakim Soria |   | cl | 23 | 11 | 7 | .636 | 2 | .182 | 14 | 26 | 4 | .154 | 60 | 60 | 20 | 18.0 | .655 |
| Rafael Soriano | GAR | mr | 27 | 7 | 4 | .571 | 3 | .429 | 14 | 18 | 5 | .278 | 54 | 54 | 23 | 18.8 | .669 |
| Jorge Sosa | NYD | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 7 | 3 | 66.5 | .599 |
| Justin Speier | RMO | mr | 33 | 2 | 0 | .000 | 2 | 1.000 | 4 | 8 | 1 | .125 | 40 | 40 | 17 | 16.9 | .661 |
| Russ Springer | HAR | mr | 38 | 10 | 8 | .800 | 1 | .100 | 12 | 23 | 7 | .304 | 55 | 55 | 22 | 18.1 | .651 |
| Tim Stauffer | REN | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 2 | .400 | 7 | 7 | 2 | 24.0 | .560 |
| Mitch Stetter* | RYS | mr | 26 | 2 | 1 | .500 | 1 | .500 | 0 | 0 | 0 | .000 | 3 | 3 | 2 | 16.0 | .542 |
| Huston Street |   | cl | 23 | 10 | 7 | .700 | 3 | .300 | 1 | 18 | 3 | .167 | 30 | 30 | 15 | 21.1 | .643 |
| Eric Stults* | REN | mr | 27 | 0 | 0 | .000 | 0 | .000 | 2 | 11 | 3 | .273 | 15 | 15 | 1 | 21.9 | .617 |
| Jeff Suppan | BBG | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 1 | 1 | 90.1 | .618 |
| Brian Tallet* | BAR | mr | 29 | 5 | 1 | .200 | 2 | .400 | 15 | 17 | 2 | .118 | 53 | 53 | 16 | 20.2 | .629 |
| Taylor Tankersley* | HAR | mr | 24 | 3 | 2 | .667 | 1 | .333 | 3 | 3 | 1 | .333 | 11 | 11 | 4 | 20.0 | .559 |
| Julian Tavarez | CTW | sp | 34 | 3 | 0 | .000 | 2 | .667 | 4 | 53 | 23 | .434 | 51 | 50 | 21 | 24.9 | .627 |
| Robinson Tejeda | FDH | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 102.3 | .586 |
| Joe Thatcher* | BBG | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 0 | 5 | 1 | .200 | 12 | 12 | 9 | 20.1 | .635 |
| Brad Thompson | CTW | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 3 | 11 | 2 | .182 | 30 | 17 | 9 | 56.7 | .598 |
| Matt Thornton* | CIO | mr | 30 | 2 | 2 | 1.000 | 0 | .000 | 4 | 27 | 6 | .222 | 38 | 37 | 8 | 20.8 | .604 |
| Mike Timlin | CEN | mr | 41 | 4 | 3 | .750 | 1 | .250 | 1 | 14 | 3 | .214 | 20 | 20 | 12 | 15.5 | .671 |
| Brett Tomko | RYS | mr | 34 | 2 | 2 | 1.000 | 0 | .000 | 0 | 7 | 3 | .429 | 21 | 12 | 9 | 50.9 | .598 |
| Salomon Torres | PHI | mr | 35 | 2 | 2 | 1.000 | 0 | .000 | 0 | 8 | 5 | .625 | 7 | 7 | 6 | 15.9 | .694 |
| Josh Towers | CIO | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 2 | .400 | 4 | 4 | 3 | 32.8 | .641 |
| Steve Trachsel | FDH | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 92.5 | .587 |
| Derrick Turnbow | CIN | mr | 29 | 10 | 9 | .900 | 1 | .100 | 1 | 31 | 8 | .258 | 46 | 46 | 25 | 22.8 | .568 |
| Jose Valverde | SOI | cl | 27 | 11 | 5 | .455 | 5 | .455 | 9 | 26 | 8 | .308 | 54 | 53 | 19 | 20.8 | .615 |
| John Van Benschoten | CIO | sp | 27 | 4 | 1 | .250 | 3 | .750 | 2 | 20 | 12 | .600 | 28 | 26 | 3 | 29.5 | .530 |
| Rick VandenHurk | CTW | sp | 22 | 2 | 0 | .000 | 2 | 1.000 | 2 | 18 | 11 | .611 | 35 | 26 | 4 | 41.5 | .570 |
| Claudio Vargas | BRK | sp | 29 | 6 | 2 | .333 | 3 | .500 | 4 | 36 | 13 | .361 | 68 | 57 | 20 | 33.6 | .587 |
| Jason Vargas* | REN | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 64.3 | .689 |
| Javier Vazquez | SOI | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 96.8 | .657 |
| Jose Veras | RYS | mr | 26 | 3 | 1 | .333 | 2 | .667 | 0 | 4 | 3 | .750 | 6 | 6 | 4 | 23.0 | .609 |
| Justin Verlander | CTW | sp | 24 | 2 | 1 | .500 | 1 | .500 | 0 | 16 | 7 | .438 | 33 | 10 | 2 | 77.7 | .632 |
| Carlos Villanueva | CIN | mr | 23 | 3 | 2 | .667 | 1 | .333 | 1 | 8 | 1 | .125 | 31 | 14 | 6 | 63.2 | .588 |
| Oscar Villarreal | HAR | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 2 | .333 | 9 | 9 | 3 | 22.6 | .626 |
| Ron Villone* | CIN | mr | 37 | 5 | 4 | .800 | 1 | .200 | 1 | 8 | 1 | .125 | 18 | 18 | 11 | 21.4 | .613 |
| Luis Vizcaino | PHI | mr | 32 | 2 | 2 | 1.000 | 0 | .000 | 0 | 5 | 1 | .200 | 9 | 9 | 7 | 16.0 | .632 |
| Edinson Volquez | BAR | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 100.4 | .622 |
| Billy Wagner* | CIN | cl | 35 | 9 | 6 | .667 | 3 | .333 | 6 | 22 | 5 | .227 | 40 | 40 | 18 | 24.1 | .595 |
| Adam Wainwright | BRK | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 103.6 | .622 |
| Tim Wakefield | CIN | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 88.3 | .622 |
| Jamie Walker* | CBB | mr | 35 | 4 | 3 | .750 | 1 | .250 | 6 | 16 | 6 | .375 | 51 | 51 | 13 | 18.5 | .623 |
| Tyler Walker | REN | mr | 31 | 2 | 2 | 1.000 | 0 | .000 | 0 | 2 | 1 | .500 | 2 | 2 | 2 | 15.0 | .600 |
| Chien-Ming Wang | RMO | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 93.6 | .627 |
| Jarrod Washburn* | NEP | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 101.4 | .635 |
| David Weathers | CEN | cl | 37 | 10 | 9 | .900 | 1 | .100 | 2 | 29 | 9 | .310 | 51 | 51 | 28 | 20.5 | .603 |
| Jeff Weaver | NEP | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 95.4 | .672 |
| Jered Weaver | BBG | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 93.0 | .641 |
| Brandon Webb | BAR | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 102.9 | .643 |
| Todd Wellemeyer | TEW | mr | 28 | 7 | 6 | .857 | 1 | .143 | 1 | 26 | 10 | .385 | 54 | 54 | 19 | 22.1 | .584 |
| David Wells* | CTW | sp | 44 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 2 | 1 | 81.2 | .615 |
| Kip Wells |   | sp | 30 | 1 | 1 | 1.000 | 0 | .000 | 2 | 5 | 2 | .400 | 12 | 12 | 6 | 18.2 | .610 |
| Jake Westbrook | ATM | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 1 | 0 | 96.3 | .621 |
| Dan Wheeler | NEP | mr | 29 | 3 | 0 | .000 | 3 | 1.000 | 14 | 24 | 8 | .333 | 58 | 58 | 23 | 20.3 | .667 |
| Sean White | BRK | mr | 26 | 2 | 1 | .500 | 1 | .500 | 2 | 13 | 2 | .154 | 24 | 24 | 11 | 21.2 | .526 |
| Woody Williams | TEW | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 101.6 | .627 |
| Dontrelle Willis* | REN | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 101.6 | .609 |
| Brian Wilson | ATM | cl | 25 | 2 | 2 | 1.000 | 0 | .000 | 2 | 6 | 1 | .167 | 13 | 13 | 5 | 19.8 | .619 |
| C.J. Wilson* | BBG | mr | 26 | 8 | 4 | .500 | 4 | .500 | 6 | 33 | 7 | .212 | 51 | 51 | 17 | 19.6 | .581 |
| Matt Wise | CIN | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 | 19.5 | .692 |
| Randy Wolf* | BRK | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 93.7 | .607 |
| Kerry Wood | RYS | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 1 | 1 | 59.2 | .552 |
| Jamey Wright | FDH | mr | 32 | 4 | 1 | .250 | 1 | .250 | 8 | 28 | 15 | .536 | 53 | 53 | 16 | 22.5 | .598 |
| Michael Wuertz | NEP | mr | 28 | 6 | 2 | .333 | 4 | .667 | 16 | 20 | 5 | .250 | 61 | 61 | 26 | 20.5 | .604 |
| Chris Young | REN | sp | 28 | 0 | 0 | .000 | 0 | .000 | 2 | 4 | 2 | .500 | 36 | 12 | 5 | 70.4 | .611 |
| Carlos Zambrano | CEN | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 103.0 | .608 |
| Barry Zito* | RYS | sp | 29 | 3 | 1 | .333 | 0 | .000 | 1 | 1 | 0 | .000 | 41 | 13 | 5 | 74.3 | .605 |
| Joel Zumaya | CBB | mr | 22 | 0 | 0 | .000 | 0 | .000 | 1 | 17 | 4 | .235 | 19 | 19 | 8 | 20.1 | .647 |